Abstract: Acoustic energy is delivered to innervated vascular that contributes to renal sympathetic nerve activity, such as innervated tissue of the renal artery and abdominal aorta. Focused acoustic energy is delivered via an intravascular device of sufficient power to ablate innervated renal or aortal tissue. Focused acoustic energy may be delivered via an intravascular or extracorporeal device to image and locate target innervated renal or aortal tissue. Intravascular, extravascular, or transvascular focused ultrasound devices provide for high precision denervation of innervated vascular to terminate renal sympathetic nerve activity.

Abstract: Apparatuses and methods facilitate delivery of optical or photoacoustic energy to innervated vascular that contributes to renal sympathetic nerve activity. The optical energy delivered may be of sufficient power to scan or image innervated renal or aortal tissue. The optical energy delivered may be of sufficient power to ablate innervated renal or aortal tissue, such as by thermal laser ablation or photoacoustic laser ablation. A catheter for intravascular or extravascular deployment supports an optical fiber arrangement comprising a coupling for receiving light from a laser light source. An optics arrangement is supported by the catheter and coupled to the optical fiber arrangement. The optics arrangement includes one or more optical elements arranged to receive the laser light and direct optical energy to target innervated tissue or a water source from which a cavitation bubble may be created and launched for acoustically shocking the target innervated tissue.

Abstract: Acoustic energy is delivered to innervated vascular that contributes to renal sympathetic nerve activity, such as innervated tissue of the renal artery and abdominal aorta. Focused acoustic energy is delivered via an intravascular device of sufficient power to ablate innervated renal or aortal tissue. Focused acoustic energy may be delivered via an intravascular or extracorporeal device to image and locate target innervated renal or aortal tissue. Intravascular, extravascular, or transvascular focused ultrasound devices provide for high precision denervation of innervated vascular to terminate renal sympathetic nerve activity.

Abstract: A fastener for holding items to a perforated wall, including fasteners for consumer and commercial uses and in displaying collector items or goods for sale, or for supporting heavy items, or for supporting shelves, platforms, wire frames and similar items on a perforated wall, the item holder having a base member with a fastener insertable into the perforated wall. The fastener has a projection with an axis preferably, but not necessarily, perpendicular to the wall and an axially extending passageway, at least a portion of the projection being displaceable laterally of its axis. An elongated pin, plunger, or cam member is insertable into the passageway in an insertion direction and is effective to displace the projection portion laterally of the projection axis for mounting the item holder to the wall. The locking mechanism may be operated by movement of the pin, plunger, or cam member axially or radially of the fastener. No tools are needed to lock or release the item holder from the perforated wall.

Abstract: A fastener for holding items to a perforated wall, including fasteners for consumer and commercial uses and in displaying collector items or goods for sale, or for supporting heavy items, or for supporting shelves, platforms, wire frames and similar items on a perforated wall, the item holder having a base member with a fastener insertable into the perforated wall. The fastener has a projection with an axis preferably, but not necessarily, perpendicular to the wall and an axially extending passageway, at least a portion of the projection being displaceable laterally of its axis. An elongated pin, plunger, or cam member is insertable into the passageway in an insertion direction and is effective to displace the projection portion laterally of the projection axis for mounting the item holder to the wall. The locking mechanism may be operated by movement of the pin, plunger, or cam member axially or radially of the fastener. No tools are needed to lock or release the item holder from the perforated wall.