Abstract: System and method for providing diagnostic, imaging procedures and surgical laser treatments generating patterns of laser light on target tissue of a patient. The system includes aiming and treatment light beams originating from the same visible laser emitting diode, a scanner for generating patterns of points of light of the generated light, a controller, and a user interface that allows the user to select one of several possible point of light patterns, adjusts the point of light intensity and/or duration.

Abstract: A method and system for thermal and non-thermal laser treatments includes a visible laser source. A laser beam in the visible spectrum is generated by the visible laser source and produces a modulated laser output. Laser controls allows the user to generate the pulsed output with variable pulse characteristics to provide selective, localized and user controlled thermal and or non-thermal biological effects at a targeted tissues. This laser system modulates the delivered laser energy to produce accurate and selective targeting of the pigmented cells of the treated tissues to induce therapeutic effects via gentle warming of the cells without significant collateral damage to surrounding tissues.

Abstract: System and method for providing diagnostic, imaging procedures and surgical laser treatments generating patterns of laser light on target tissue of a patient. The system includes aiming and treatment light beams originating from the same visible laser emitting diode, a scanner for generating patterns of points of light of the generated light, a controller, and a user interface that allows the user to select one of several possible point of light patterns, adjusts the point of light intensity and/or duration.

Abstract: System and method for providing diagnostic, imaging procedures and surgical laser treatments generating patterns of laser light on target tissue of a patient. The system includes aiming and treatment light beams originating from the same visible laser emitting diode, a scanner for generating patterns of points of light of the generated light, a controller, and a user interface that allows the user to select one of several possible point of light patterns, adjusts the point of light intensity and/or duration.

Abstract: A method and system for thermal and non-thermal laser treatments includes a visible laser source. A laser beam in the visible spectrum is generated by the visible laser source and produces a modulated laser output. Laser controls allows the user to generate the pulsed output with variable pulse characteristics to provide selective, localized and user controlled thermal and or non-thermal biological effects at a targeted tissues. This laser system modulates the delivered laser energy to produce accurate and selective targeting of the pigmented cells of the treated tissues to induce therapeutic effects via gentle warming of the cells without significant collateral damage to surrounding tissues.

Abstract: System and method for providing diagnostic, imaging procedures and surgical laser treatments generating patterns of laser light on target tissue of a patient. The system includes aiming and treatment light beams originating from the same visible laser emitting diode, a scanner for generating patterns of points of light of the generated light, a controller, and a user interface that allows the user to select one of several possible point of light patterns, adjusts the point of light intensity and/or duration.

Abstract: A lens assembly generally includes an ophthalmic contact lens, a rotating collar configured for rotation around at least a portion of an outer surface of the lens, and an indexing assembly configured to provide tactile feedback to a user in the form of increased resistance to relative rotation of the lens and the collar at uniformly spaced indexing positions.

Abstract: Systems, apparatuses, and methods for a compact surgical device include a laser unit and one or more laser outlet assemblies. The laser unit has a power regulator, one or more diode laser assemblies, each having a single diode laser source, and a laser trigger mechanism. The laser unit can emit an aiming light beam and a treatment laser beam either both from the same single diode laser or from two separate single diode lasers. The beam can pass through the one or more laser outlet assemblies. The aiming light beam can have a first energy level. The treatment laser beam can have a second energy level that is substantially greater than the first energy level of the aiming light beam.

Abstract: The present invention involves selectively breaking down or altering a blocking tissue by irradiating the blocking tissue with a laser irradiation. Breaking down the blocking tissue allows the delivery of therapeutic agents through the blocking tissue to a target tissue. An area of the blocking tissue is selected for treatment. The selected area is irradiated with a laser to induce an alteration or breakdown of the blocking tissue. Areas not irradiated are not affected. Once the selected area of the blocking tissue is treated, a therapeutic agent can be delivered to the selected area and passed through the altered or broken down blocking tissue to the target tissue. The blocking tissue will then undergo a healing response after a period of time. The present invention may be used to treat the retina or subretinal space of a patient's eye through the blocking tissue of the Retinal Pigment Epithelium (RPE).

Abstract: The invention is based, at least in part, on the discovery that if a tissue is irradiated with a sublethal dose of radiation, e.g., from a laser, that pigmented cells in the tissue are selectively stimulated to proliferate and to produce higher levels of certain mitogenic factors and growth factors such as platelet derived growth factor (PDGF). In particular, the various parameters of a pulsed laser beam, such as power, pulse duration, total radiation energy (‘fluence’), wavelength, and if multiple pulses are used, the pulse rate and total number of pulses, are carefully selected and controlled to minimize killing the irradiated pigmented cells.

Abstract: Systems, apparatuses, and methods for a compact surgical device include a laser unit and one or more laser outlet assemblies. The laser unit has a power regulator, one or more diode laser assemblies, each having a single diode laser source, and a laser trigger mechanism. The laser unit can emit an aiming light beam and a treatment laser beam either both from the same single diode laser or from two separate single diode lasers. The beam can pass through the one or more laser outlet assemblies. The aiming light beam can have a first energy level. The treatment laser beam can have a second energy level that is substantially greater than the first energy level of the aiming light beam.

Abstract: A gonio lens is provided including a contact lens element and a geometric reference member. The contact lens element has an optical axis, a concave posterior contact surface to be placed in optical contact with the cornea of a patient's eye, and an anterior surface. The geometric reference member, such as a scale, is provided near the concave posterior contact surface of the contact lens element. The configuration and location of the geometric reference member are chosen to provide an image of the geometric reference member adjacent to an image of the periphery of the anterior chamber of the eye of a patient within a field of view of the contact lens element when the contact lens element is placed on the eye of a patient. The two images are formed relative to each other such that they are simultaneously in focus to permit visual comparison between the two.

Abstract: The present invention involves selectively breaking down or altering a blocking tissue by irradiating the blocking tissue with a laser irradiation. Breaking down the blocking tissue allows the delivery of therapeutic agents through the blocking tissue to a target tissue. An area of the blocking tissue is selected for treatment. The selected area is irradiated with a laser to induce an alteration or breakdown of the blocking tissue. Areas not irradiated are not affected. Once the selected area of the blocking tissue is treated, a therapeutic agent can be delivered to the selected area and passed through the altered or broken down blocking tissue to the target tissue. The blocking tissue will then undergo a healing response after a period of time. The present invention may be used to treat the retina or subretinal space of a patient's eye through the blocking tissue of the Retinal Pigment Epithelium (RPE).

Abstract: A method of damaging pigmented intraocular cells, a patient with a disease, which involves selectively damaging pigmented cells in an intraocular area by irradiating the area with laser radiation of radiant exposure between about 0.01 and about 5 Joules/cm.sup.2, while sparing nonpigmented cells and collagenous structures within the irradiated area. The method is useful for the treatment of glaucoma, intraocular melanoma, and macular edema.

Abstract: A method and device for nasolacrimal duct occlusion during eye medication provides a device having a pair of joined legs terminating in angled elements for fitting into the medial canthal area and compressing the nasolacrimal ducts. The device is placed over the nasal bridge during, and for a short time after, eye medication.

Abstract: Apparatus and non-invasive method for focal transcleral destruction of living human eye tissue. The apparatus includes a pair of conical-shaped probes, each probe filled with an ionic probe solution and having therein an electrode connected to a constant current supply. The method includes lowering the narrow aperture end of the probes onto the conjunctiva overlying the target tissue, each probe being approximately 90.degree. apart from the other about the eye surface. The probes of the invention have opposite polarity to enable transfer of ions between the probes. Electrodes are of appropriate conductive materials.

Abstract: A non-invasive method for treatment of glaucoma by selective ablation of sclera of a living human eye. The method includes providing a slit lamp laser system including a source of pulsed laser light and a gonio lens adapted to withstand pulsed laser light having energy of greater than 100 mJ pulse. The method further includes focusing the laser light on the sclera, and adjusting the light to a spot diameter of between 100 and 300 microns, a pulse width of between 1 and 30 microseconds, a pulse energy of between 75 andn 250 mJ, and a cone angle of between 8 and 15 degrees. The sclera is then repeatedly illuminated with single pulses of laser light until the sclera is perforated.

Abstract: A non-invasive method for focal transcleral destruction of living human eye tissue. The method includes providing a conical-shaped probe, filled with a neutral saline solution and having inserted therein an electrode connected to the positive terminal of a constant current supply. The narrow aperture ends of the probe is lowered onto the conjunctiva overlying the target tissue, in about 20-30 locations with a current in the range from about 3.0-4.0 milliamps for about 30 seconds to 5 minutes at each location.