Abstract: An assembly of a drug delivery device with a longitudinal axis (L) is given, comprising a body (1) with a proximal end (2) and a distal end (3). The drug delivery device further comprises a drive assembly and a first button member (4). The drive assembly is at least partially arranged within the body (1) and is adapted to facilitate dispense of a medicinal product. The first button member (4) acts on the drive assembly to prepare the drug delivery device for dispensing the medicinal product. The first button member (4) is adapted to be detachable from the body (1) after the preparation of the drug delivery device is completed.

Abstract: An assembly of a drug delivery device comprises a body (10) having a distal end (11) and a proximal end (12), a drive assembly (4) arranged substantially within the body (10) to facilitate dispense of a medicinal product and a button member (5) arranged at the proximal end (12) of the body (10) and adapted to act upon the drive assembly (4). The drive assembly (4) has an initial pre-ready state, a transient state and a ready state; in the pre-ready and transient states the button member (5) is twistable with respect to the body (10) to act upon the drive assembly (4) and wherein in the ready state the button member (5) is axially moveable but not substantially twistable with respect to the body (10) to act upon the drive assembly (4) to dispense a dose of the medicinal product.

Abstract: A plate holder is provided to facilitate percutaneous introduction of a bone plate, positioning of the plate on a bone surface, and stabilizing the plate while a fastener is inserted through the plate into the bone. The plate holder includes a proximal handle, a distal mount, and an arm extending between the handle and the mount. The mount includes a first portion which seats within a slot on the shaft of a plate, and a second portion at which the shaft is coupled and which includes a tapered proximal side. A set screw hole is provided through the first and second portions, and a set screw is provided therein. When the first portion is seated in a compression slot of a plate and the set screw is driven to seat, the set screw locks the mount to the plate.

Abstract: The present invention provides a syringe assembly for a medication pump, such as an insulin pump, or the like that includes a pair of protruding structures at one end that mate with the typical pair of opposed recesses or other notch structures of the syringe assembly mating portion of the pump, without the use of a cap structure and needle member, and that may be manufactured primarily from a relatively inexpensive plastic material or the like, while still providing the medication supply back-pressure required to be adequately sensed by the pump electronics, such that the pump accepts the syringe assembly and is “primed” for proper operation.

Abstract: A plate holder is provided to facilitate percutaneous introduction of a bone plate, positioning of the plate on a bone surface, and stabilizing the plate while a fastener is inserted through the plate into the bone. The plate holder includes a proximal handle, a distal mount, and an arm extending between the handle and the mount. The mount includes a first portion which seats within a slot on the shaft of a plate, and a second portion at which the shaft is coupled and which includes a tapered proximal side. A set screw hole is provided through the first and second portions, and a set screw is provided therein. When the first portion is seated in a compression slot of a plate and the set screw is driven to seat, the set screw locks the mount to the plate.

Abstract: A drug delivery device (10) is given, comprising a body (12) and a moveable button member (14), wherein in a pre-ready state of the drug delivery device (10) there is a misalignment between the body (12) and the button member (14). This misalignment is perceivable by a user of the drug delivery device (10). In a ready state of the drug delivery device (10), the button member (14) and the body (12) are aligned and the alignment is perceivable by a user of the drug delivery device (10).

Abstract: A drug delivery device (4) for dispensing one or more doses of a drug is provided. The device (4) comprises a drive member (1) for driving a piston rod (5) and a dose member (46) for actuating the drive member (1). The piston rod (5) is coupled to the drive member (1) such that a relative translational movement of the drive member (1) and the piston rod (5) is allowed and a relative rotational movement is prevented. The drive member (1) is configured to be driven by the dose member (46) around the longitudinal axis in a first (110) and a second rotational direction (111) opposite to each other. Furthermore, a drug delivery device (4) is provided, wherein the drive member (1) has stable and unstable states and wherein in an unstable state the drive member (1) is biased by biasing means (3) towards a stable state.

Abstract: An assembly of a drug delivery device with a longitudinal axis (L) is given, comprising a body (1) with a proximal end (2) and a distal end (3). The drug delivery device further comprises a drive assembly and a first button member (4). The drive assembly is at least partially arranged within the body (1) and is adapted to facilitate dispense of a medicinal product. The first button member (4) acts on the drive assembly to prepare the drug delivery device for dispensing the medicinal product. The first button member (4) is adapted to be detachable from the body (1) after the preparation of the drug delivery device is completed.

Abstract: A distal tibia plating system includes anterolateral and medial plates. The anterolateral plate includes a shaft with both threaded first fastener holes and compression slots along its length. The head includes a first row of four threaded fastener holes arranged transversely to the longitudinal axis, a non-threaded compression screw hole, and a plurality of distal tabs. Each tab includes a ring with a single threaded fastener hole and a bridge that couples the ring to the distal end of the plate. The bridge is configured to bend preferentially in a desired direction and to allow tab removal. The medial plate is a low profile plate including a shaft and a relatively enlarged distal head. Several fasteners can be used with the plates. A plate holder is provided to maneuver the plates subcutaneously.

Abstract: An assembly of a drug delivery device comprises a body (10) having a distal end (11) and a proximal end (12), a drive assembly (4) arranged substantially within the body (10) to facilitate dispense of a medicinal product and a button member (5) arranged at the proximal end (12) of the body (10) and adapted to act upon the drive assembly (4). The drive assembly (4) has an initial pre-ready state, a transient state and a ready state; in the pre-ready and transient states the button member (5) is twistable with respect to the body (10) to act upon the drive assembly (4) and wherein in the ready state the button member (5) is axially moveable but not substantially twistable with respect to the body (10) to act upon the drive assembly (4) to dispense a dose of the medicinal product.

Abstract: A drive member for driving a piston rod in a drug delivery device is provided. The drive member is configured to be driven in a rotational movement by an actuating member. The drive member comprises a track for transmitting a driving load from the actuating member to the drive member. The track comprises both sections running in a distal and sections running in a proximal direction of the drive member. Moreover, a drug delivery device comprising such a drive member is provided.

Abstract: The present invention relates to an assembly for a drug delivery device comprising a proximal end, a distal end and a moveable member, a dose member, a fixed member and coupling means, wherein in a first state, the moveable member is moveable in an axial direction with respect to the fixed member and the dose member and the coupling means retains the dose member to the fixed member, and wherein in a second state of the assembly, the moveable member is permanently connected with the dose member by means of the coupling means and the dose member is released from the fixed member and the assembly is configured to set and dispense a dose of a fluid medicinal product out of an assembled cartridge by movement of the dose member. Furthermore it relates to a method for setting-up a drug delivery device.

Abstract: A button member (5) for operating a drive assembly (4) of a drug delivery device comprises a first portion being accessible by a user, a second portion in operative connection with the drive assembly (4), said second portion comprising a first guiding track (51) having a first track portion (511) in a first direction and a second track portion (512) in second direction, wherein the first track portion (511) is adapted to restrict the movement of the button member (5) to a substantially rotational motion, and wherein the second track portion (512) is adapted to restrict the movement of the button member (5) to an axial motion.

Abstract: A drive member for driving a piston rod in a drug delivery device is provided. The drive member is configured to be driven in a rotational movement by an actuating member. The drive member comprises a track for transmitting a driving load from the actuating member to the drive member. The track comprises both sections running in a distal and sections running in a proximal direction of the drive member. Moreover, a drug delivery device comprising such a drive member is provided.

Abstract: A periarticular bone plate for the internal fixation of a fractured, proximal tibia of a surgical patient includes a shaft member connected to a head member, a top surface, a bottom surface, a posterior edge, an anterior edge and a plurality of holes extending between the top and bottom surfaces for receiving fasteners for attaching the plate to the bone. The head member is offset relative to the shaft member in each of a frontal and sagittal planes of the proximal tibia.

Abstract: A periarticular bone plate for the internal fixation of a fractured, proximal tibia of a surgical patient includes a shaft member connected to a head member, a top surface, a bottom surface, a posterior edge, an anterior edge and a plurality of holes extending between the top and bottom surfaces for receiving fasteners for attaching the plate to the bone. The head member is offset relative to the shaft member in each of a frontal and sagittal planes of the proximal tibia.

Abstract: A surgical retractor assembly is disclosed that includes a bone plate and a retractor. The bone plate has a tapered end portion. The retractor includes a base having (i) a body defining a bottom surface and a distal portion, the distal portion defining a distal surface, (iii) a first pair of tabs extending from the body that are spaced apart from each other, and (iv) a second pair of tabs extending from the body that are spaced apart from each other. The retractor further includes a handle attached to the base. The first pair of tabs and the bottom surface define a first plate space. The second pair of tabs and the distal surface define a second plate space.

Abstract: A surgical retractor assembly is disclosed that includes a bone plate and a retractor. The bone plate has a tapered end portion. The retractor includes a base having (i) a body defining a bottom surface and a distal portion, the distal portion defining a distal surface, (iii) a first pair of tabs extending from the body that are spaced apart from each other, and (iv) a second pair of tabs extending from the body that are spaced apart from each other. The retractor further includes a handle attached to the base. The first pair of tabs and the bottom surface define a first plate space. The second pair of tabs and the distal surface define a second plate space. The retractor is positionable in relation to the bone plate between a first position and a second position. When the retractor is positioned in the first position, (i) the bone plate is positioned in the first plate space, and (ii) the bone plate is located outside of the second plate space.

Abstract: A periarticular bone plate for the internal fixation of a fractured, proximal tibia of a surgical patient includes a shaft member connected to a head member, a top surface, a bottom surface, a posterior edge, an anterior edge and a plurality of holes extending between the top and bottom surfaces for receiving fasteners for attaching the plate to the bone. The head member is offset relative to the shaft member in each of a frontal and sagittal planes of the proximal tibia.

Abstract: A periarticular bone plate for the internal fixation of a fractured, proximal tibia of a surgical patient includes a shaft member connected to a head member, a top surface, a bottom surface, a posterior edge, an anterior edge and a plurality of holes extending between the top and bottom surfaces for receiving fasteners for attaching the plate to the bone. The head member is offset relative to the shaft member in each of a frontal and sagittal planes of the proximal tibia.