Abstract: An endovascular device tip assembly and method of making the same, incorporating a tip device with a first and second flange, usable with catheters and other suitable endovascular devices is provided. The tip assembly incorporates a tip device by providing a counterbore within a primary bore of a tubular end portion of an endovascular device. The tip device is fitted securely within the counterbore by placing the first flange within the counterbore and the second flange on the outside of the end portion.

Abstract: A method and device includes advancing a first stent and a second stent into a stenosed region of a blood vessel to protect or shield the vessel from possible blockage. The delivery device may include placement rings, selectively engagable by positioning members disposed on the outer wall of in inner catheter. The positioning members and the placement rings may be utilized to accurately place multiple stents within an afflicted vessel, in a single invasive procedure.

Abstract: A method of loading a medical device into a delivery system includes providing a two-stage shape memory alloy at a temperature at which at least a portion of the alloy includes austenite. A stress which is sufficient to form R-phase from at least a portion of the austenite is applied to the medical device at the temperature. A delivery configuration of the medical device is obtained, and the medical device is loaded into a restraining member. Preferably, the delivery configuration of the medical device includes stress-induced R-phase.

Abstract: Medical devices, as well as methods of treatment and manufacturing such devices, are provided for applying vascular therapy locally within the body vessel. The medical devices include an expandable tubular frame and a sleeve or graft material. The medical devices can be used for local delivery of a therapeutic agent within a body vessel or a tamponade for a lacerated body vessel, while simultaneously allowing perfusion of fluid or blood flow distal of the implanted medical device. The tubular frame of the medical device may have a proximal non-expanding portion and a distal self-expanding support structure. The self-expanding support structure can expand radially outward to urge the graft material to contact the wall of the body vessel. In the expanded configuration, a portion of the device allows fluid flow to continue while the sleeve is against the body vessel wall.

Abstract: An intraluminal delivery system for sequentially deploying two or more implantable medical devices includes two or more such devices arranged longitudinally adjacent to each other about an inner catheter. One or more separator bands are slideably disposed about the inner catheter, and each of the bands is positioned between adjacent medical devices. An outer catheter, which is proximal to the medical devices, overlies the inner catheter but does not overlie the medical devices. A tubular sheath overlies the outer catheter, the one or more separator bands, and the medical devices. Relative motion between the tubular sheath and the inner catheter allows the medical devices to be sequentially deployed at one or more treatment sites, and relative motion between the inner catheter and the outer catheter allows a distal tip of the inner catheter to be retracted after deployment of each device.

Abstract: An endovascular device tip assembly and method of making the same, incorporating a tip device with a first and second flange, usable with catheters and other suitable endovascular devices is provided. The tip assembly incorporates a tip device by providing a counterbore within a primary bore of a tubular end portion of an endovascular device. The tip device is fitted securely within the counterbore by placing the first flange within the counterbore and the second flange on the outside of the end portion.

Abstract: An endovascular device tip assembly and method of making the same, incorporating a tip device with a first and second flange, usable with catheters and other suitable endovascular devices is provided. The tip assembly incorporates a tip device by providing a counterbore within a primary bore of a tubular end portion of an endovascular device. The tip device is fitted securely within the counterbore by placing the first flange within the counterbore and the second flange on the outside of the end portion.

Abstract: An expandable stent radially adjustable between a collapsed state and an expanded state. The stent generally includes a main body and a plurality of connector segments. The main body has first and second ends, a longitudinal axis extending from the first end to the second end, and a plurality of ring structures. Each of the plurality of connector segments joins adjacent ring structures. Some ring structures may be connected by a pair of diamond connector segments that define a diamond-shaped portion when the stent is in the expanded state. Some ring structures may be connected by flex connector segments oriented to permit rotation of the second ring structure about the longitudinal axis during radial expansion of the stent.

Abstract: A method and device includes advancing a first stent and a second stent into a stenosed region of a blood vessel to protect or shield the vessel from possible blockage. The delivery device may include placement rings, selectively engagable by positioning members disposed on the outer wall of in inner catheter. The positioning members and the placement rings may be utilized to accurately place multiple stents within an afflicted vessel, in a single invasive procedure.

Abstract: A system for permitting substantially bloodless percutaneous entry into an artery or vein of a patient. The system comprises a needle assembly, a needle hub attachment assembly having a hemostatic segment, and a wire guide inserter (curve straightener) or a wire guide holder also having a hemostatic segment. The components are assembled in a leak-free arrangement, and a fluid passageway for withdrawing blood is established through the system. Each of the hemostatic segments opens to permit passage of a wire guide therethrough, but re-seals to prevent flow of blood therethrough. The needle hub attachment assembly preferably includes a fluid-receiving chamber to permit the clinician to see the first squirt of blood as it enters the system.

Abstract: A method of characterizing phase transformations of a shape memory material specimen entails recording data from the specimen during heating and cooling. The temperature of the specimen is changed in a first direction to a first temperature sufficient to define a first inflection and a second inflection in the data being recorded. The temperature of the specimen is changed in a second direction to a second temperature sufficient to define a third inflection in the data. The third inflection is formed by overlapping primary and secondary sub-inflections. The temperature of the specimen is changed in the first direction to a third temperature sufficient to define the first inflection but not sufficient to define the second inflection. The temperature of the specimen is then changed in the second direction to a fourth temperature sufficient to define the secondary sub-inflection in the data being recorded.

Abstract: An endovascular device tip assembly and method of making the same, incorporating a tip device with a first and second flange, usable with catheters and other suitable endovascular devices is provided. The tip assembly incorporates a tip device by providing a counterbore within a primary bore of a tubular end portion of an endovascular device. The tip device is fitted securely within the counterbore by placing the first flange within the counterbore and the second flange on the outside of the end portion.

Abstract: A process to load a medical device comprising a shape memory material into a delivery system is described herein. According to one aspect, the method includes applying a force to the medical device to obtain a delivery configuration thereof, where the device is at a first temperature within an R-phase temperature range of the shape memory material during application of the force. The medical device is cooled in the delivery configuration to a second temperature at or below a martensite finish temperature of the shape memory material. The force is then removed from the medical device, and the device is loaded into a delivery system. Preferably, the medical device substantially maintains the delivery configuration during the loading process.

Abstract: An endovascular device tip assembly and method of making the same, incorporating a radiopaque marker usable with catheters and other suitable endovascular devices is provided. The tip assembly incorporates a radiopaque marker device by providing a counterbore within a primary bore of a tubular tip of an endovascular device. The marker device is fitted securely within the counterbore and the tubular tip is further deformed distally of the marker in order to secure the marker within the device.

Abstract: A method and device includes advancing an anchor stent assembly and a second stent into a stenosed region of a blood vessel to protect or shield the vessel from possible blockage. The anchor stent assembly may include an anchor stent and a cover made of submucosal tissue (SIS). The cover is delivered in a dried, compressed, condition and is later softened and expanded by exposure to the flow of blood. The second stent may then be advanced within the cover and dilated to press the cover against the stenosed region of the vessel, thus protecting the vessel from emboli formed of stenosis breakage.

Abstract: An embolic protection device includes a foam body attached to a plurality of flexible struts. The foam body has a generally conical geometry and the bottom of the conical geometry having a generally conical recess. The filter portion has pores sized such that blood cells can pass through the foam body, but larger material such as objects would be trapped in the recess. Each strut is attached along the periphery of the foam body and extend from the first end of the foam body to a connection point located proximate the first end.

Abstract: A device for capturing emboli during treatment of a stenotic lesion in a body vessel is disclosed. The device comprises a base having expanded and collapsed states, and proximal and distal portions. The distal portion has a support portion configured to deploy in the body vessel when the base is in the expanded state. The device further comprises a filter portion disposed on the distal portion of the base. The filter portion includes a lip extending to a filter body to a filter end. The filter portion is configured to engage the support portion when deployed to define an opening of the filter portion for capturing emboli. The device further comprises a collector through which the base is slideably disposed for delivery and retrieval of the device.

Abstract: An embolic protection device for deployment in a body vessel is provided for filtering emboli within the body vessel. The embolic protection device generally includes a filter having a plurality of openings formed therethrough and an extraction element configured to be movable with respect to the filter between a non-extraction position and an extraction position. The extraction element is located distally of the filter when in the non-extraction position so as to allow the filter to open into an expanded state to collect the emboli. Additionally, the extraction element is disposed about at least a portion of the filter when in the extraction position so as to close the filter into a collapsed state and to permit the embolic protection device to be extracted from the body vessel.

Abstract: An embolic protection device including a core wire and a basket is disclosed. The basket includes struts and a filter portion formed from a cannula. The struts extend from a first end of the basket to the second end of the basket. The filter portion extends from the struts and is formed unitarily therewith. The filter portion extends between a middle portion of the basket and the second end of the basket and includes openings in the cannula configured to allow the passage of blood cells therethrough.

Abstract: An embolic protection device includes a basket formed from flexible struts. The struts extend from a first end of the basket to the second end of the basket. The struts form a middle portion of the basket where the struts extend substantially perpendicular to a longitudinal axis, running between the first and second end of the basket.