Abstract: The present invention relates to the use of tesidolumab for the prevention or treatment of transplant rejection and in particular antibody mediated rejection of allografts.

Abstract: A jetting device and/or fluid module include a module body defining a passageway extending through the module body and also partially defining a fluid chamber, a nozzle supported by the module body, a valve element at least partially within the fluid chamber, a biasing element contacting the valve element and also contacting the module body, and a sealing member contacting the periphery of the valve element and configured to partially define the fluid chamber. The nozzle defines a fluid outlet that is in fluid communication with the fluid chamber. The valve element has an upper portion outside of the fluid chamber that is adapted for contact with the drive pin, and the biasing element is configured to apply a spring force to the valve element. The valve element is configured to cause a droplet of the fluid to be jetted from the fluid outlet when the valve element is moved in the direction toward the nozzle.

Abstract: A jetting device and/or fluid module includes a nozzle with a fluid outlet, a body including a fluid chamber and a fluid inlet in fluid communication with the fluid chamber, and a valve seat disposed in the fluid chamber, where the valve seat includes an opening in fluid communication with the fluid outlet. The jetting device also includes a movable element having a top portion and a bottom portion, where the top portion is disposed external to the fluid chamber and arranged to be contacted by a reciprocating drive pin, and where the bottom portion is disposed within the fluid chamber. Finally, the jetting device also includes a sealing member contacting the movable element between the top portion and the bottom portion, where the sealing member also contacts the body, and defines a portion of a boundary of the fluid chamber to seal the fluid chamber.

Abstract: A jetting device and/or fluid module includes a nozzle with a fluid outlet, a body including a fluid chamber and a fluid inlet in fluid communication with the fluid chamber, and a valve seat disposed in the fluid chamber, where the valve seat includes an opening in fluid communication with the fluid outlet. The jetting device also includes a movable element having a top portion and a bottom portion, where the top portion is disposed external to the fluid chamber and arranged to be contacted by a reciprocating drive pin, and where the bottom portion is disposed within the fluid chamber. Finally, the jetting device also includes a sealing member contacting the movable element between the top portion and the bottom portion, where the sealing member also contacts the body, and defines a portion of a boundary of the fluid chamber to seal the fluid chamber.

Abstract: A jetting device and/or fluid module include a module body defining a passageway extending through the module body and also partially defining a fluid chamber, a nozzle supported by the module body, a valve element at least partially within the fluid chamber, a biasing element contacting the valve element and also contacting the module body, and a sealing member contacting the periphery of the valve element and configured to partially define the fluid chamber. The nozzle defines a fluid outlet that is in fluid communication with the fluid chamber. The valve element has an upper portion outside of the fluid chamber that is adapted for contact with the drive pin, and the biasing element is configured to apply a spring force to the valve element. The valve element is configured to cause a droplet of the fluid to be jetted from the fluid outlet when the valve element is moved in the direction toward the nozzle.

Abstract: A system and method for storing resumes and job posting using a common skills database is provided, including: a server configured to operate a candidate interface module and a recruiter interface module; the skills database accessible by the candidate interface module and the recruiter interface module; the candidate interface module configured to store job postings including one or more skills from the skills database; and the recruiter interface module configured to store resumes including one or more skill from the skills database.

Abstract: A jetting device and/or fluid module includes a nozzle with a fluid outlet, a body including a fluid chamber and a fluid inlet in fluid communication with the fluid chamber, and a valve seat disposed in the fluid chamber, where the valve seat includes an opening in fluid communication with the fluid outlet. The jetting device also includes a movable element having a top portion and a bottom portion, where the top portion is disposed external to the fluid chamber and arranged to be contacted by a reciprocating drive pin, and where the bottom portion is disposed within the fluid chamber.

Abstract: A jetting device and/or fluid module includes a nozzle with a fluid outlet, a body including a fluid chamber and a fluid inlet in fluid communication with the fluid chamber, and a valve seat disposed in the fluid chamber, where the valve seat includes an opening in fluid communication with the fluid outlet. The jetting device also includes a movable element having a top portion and a bottom portion, where the top portion is disposed external to the fluid chamber and arranged to be contacted by a reciprocating drive pin, and where the bottom portion is disposed within the fluid chamber.

Abstract: Modular devices for jetting a fluid material and components for modular jetting devices. The devices may include a pressurized air or positive displacement pump fluid supply module to supply a fluid module inlet. A syringe may feed material through a check valve to a positive displacement pump, which feeds material through another check valve to the fluid module. Inside the fluid module is a valve element moved to contact a valve seat and jet a droplet of material by contact between an external drive pin and a movable element of the fluid module. Either a piezoelectric actuator, a pneumatic actuator, or another actuator may move the drive pin. A controller may coordinate the supply of fluid from the positive displacement pump with the rate at which material is jetted. The fluid module and positive displacement pump are easily removable from the jetting device.

Abstract: Method for seismic prospecting using counter-rotating (207-208) eccentric-mass (201, 202) vibrator (CREMV) technology adapted as vibrator sources for seismic prospecting to produce controlled sweeps, as in the manner used in modern seismic prospecting, but with large forces at low frequencies, e.g. forces >275 kN at frequencies between 1 and 5 Hz. This is achieved by adapting the CREMV to enable rotational frequency and the eccentricity (205, 206) of the masses relative to their rotation axes (203-204) to be varied independently and simultaneously, and by designing the CREMV such that the radius of rotation of the center of mass of each rotating mass is on the order of 50 cm or more. The low frequency data obtained from such a seismic source enables improved detection and resolution of subsurface structures and better determination of subsurface properties.

Abstract: Method for seismic prospecting using counter-rotating (207-208) eccentric-mass (201, 202) vibrator (CREMV) technology adapted as vibrator sources for seismic prospecting to produce controlled sweeps, as in the manner used in modern seismic prospecting, but with large forces at low frequencies, e.g. forces >275 kN at frequencies between 1 and 5 Hz. This is achieved by adapting the CREMV to enable rotational frequency and the eccentricity (205, 206) of the masses relative to their rotation axes (203-204) to be varied independently and simultaneously, and by designing the CREMV such that the radius of rotation of the center of mass of each rotating mass is on the order of 50 cm or more.

Abstract: Method for marine seismic acquisition using both monopole (91) and dipole (92) source types. Through a combination of source design and operation and/or combination or summing of the data in a processing step, the source ghost is either attenuated or, if desired, enhanced (93). The properties of the two different source types allow them to be adjusted so that the first down going wave from each has either opposite polarity or the same polarity, whereas the source-ghost wave will have, respectively same polarity or opposite polarity. This allows cancellation or enhancement of the source ghost. If the survey also employs two-component sensor acquisition, then the combined data sets may be both sensor de-ghosted and source de-ghosted.

Abstract: Devices for sensing gradients are constructed from material whose properties change in response to gradients. One embodiment of the device is a transducer (200) for sensing gradients that includes the material (210) and two or more electrodes (240, 270) coupled to the material. In one embodiment, gradients in a surrounding medium (110) modify the energy gap of the material in the transducer (130) producing a diffusion current density (150). The material is configured to connect to a current or voltage measurement device (520, 530, 540) where a measurement is used to determine the gradient in the medium (160). The devices can be used to measure pressure, temperature, and/or other properties. The transducer can be built on the same substrate as complementary circuitry. A transducer made of Indium. Antimonide is used in marine seismology to measure pressure gradients.

Abstract: Method for marine seismic acquisition using both monopole (91) and dipole (92) source types. Through a combination of source design and operation and/or combination or summing of the data in a processing step, the source ghost is either attenuated or, if desired, enhanced (93). The properties of the two different source types allow them to be adjusted so that the first down going wave from each has either opposite polarity or the same polarity, whereas the source-ghost wave will have, respectively same polarity or opposite polarity. This allows cancellation or enhancement of the source ghost. If the survey also employs two-component sensor acquisition, then the combined data sets may be both sensor de-ghosted and source de-ghosted.

Abstract: Method for separating different seismic energy modes in the acquisition (65) of seismic survey data by using sensors that preferentially record a single mode (63), optionally combined with a source that preferentially transmits that mode.

Abstract: Modular devices for jetting a fluid material and components for modular jetting devices. The devices may include a pressurized air or positive displacement pump fluid supply module to supply a fluid module inlet. A syringe may feed material through a check valve to a positive displacement pump, which feeds material through another check valve to the fluid module. Inside the fluid module is a valve element moved to contact a valve seat and jet a droplet of material by contact between an external drive pin and a movable element of the fluid module. Either a piezoelectric actuator, a pneumatic actuator, or another actuator may move the drive pin. A controller may coordinate the supply of fluid from the positive displacement pump with the rate at which material is jetted. The fluid module and positive displacement pump are easily removable from the jetting device.

Abstract: A building panel, a shingle and a flooring tile are all provided including a reticulated foam body having a weather resistant coating made from a material selected from a group consisting of a polymer, a ceramic glaze and mixtures thereof. In addition, a method of producing these products is also provided.

Abstract: A building panel, a shingle and a flooring tile are all provided including a reticulated foam body having a weather resistant coating made from a material selected from a group consisting of a polymer, a ceramic glaze and mixtures thereof. In addition, a method of producing these products is also provided.

Abstract: Devices for sensing gradients are constructed from material whose properties change in response to gradients. One embodiment of the device is a transducer (200) for sensing gradients that includes the material (210) and two or more electrodes (240, 270) coupled to the material. In one embodiment, gradients in a surrounding medium (110) modify the energy gap of the material in the transducer (130) producing a diffusion current density (150). The material is configured to connect to a current or voltage measurement device (520, 530, 540) where a measurement is used to determine the gradient in the medium (160). The devices can be used to measure pressure, temperature, and/or other properties. The transducer can be built on the same substrate as complementary circuitry. A transducer made of Indium. Antimonide is used in marine seismology to measure pressure gradients.

Abstract: Method for designing a converted mode (PS or SP) seismic survey to accomplish specified vertical and lateral resolution objectives at target depth. An equation (181) is provided for determining the minimum bandwidth required for a desired vertical resolution at a selected scattering angle, as a function of incident and reflected wave velocities, one of which is the P-wave velocity and the other is the S-wave velocity. A second equation (182) is provided for determining migration acceptance angle from the desired vertical and lateral resolutions. Source and receiver apertures may then be determined by ray tracing. Finally, a third equation (183) is provided for the maximum bin size to avoid aliasing, given the migration acceptance angle and a maximum frequency needed to achieve the bandwidth requirement. Source and receiver spacing may then be based on the maximum bin size.