Abstract: The present invention is related to agents capable of binding to and inhibiting or antagonizing the action of IL-11 and/or or IL-11RA for the treatment and/or prevention of abnormal uterine bleeding, which comprises heavy menstrual bleeding, prolonged bleeding, altered bleeding pattern, dysmenorrhea, as well as of the underlying diseases leiomyoma and endometriosis and the use of the agent to inhibit menstruation. Furthermore, the invention provides novel IL-11 antibodies.

Abstract: In one aspect, the present disclosure provides a nozzle for a 3D printing system. The nozzle may include a flowpath with a material inlet and a material outlet. The nozzle may further include a valve in fluid communication with the flowpath between the material inlet and the material outlet, where the valve includes a closed state and an open state, where in the closed state the valve obstructs the flowpath between the material inlet and the material outlet, and where in the open state the material inlet is in fluid communication with the material outlet. The nozzle may further include a compensator in fluid communication with the flowpath, where the compensator includes a contracted state associated with the open state of the valve and an expanded state associated with the closed state of the valve.

Abstract: An alignment system for approaching a vehicle to a target object spatially spaced therefrom, including an object detection device attached to the vehicle and a coupling element, which in an end position detachably holds the target object, the object detection device being aligned in the direction of the target object and the data from the object detection device being used to generate an image in which the target object together with a guide marker can be seen during the approach of the vehicle. The guide marker is applied to at least one component of the vehicle arranged in an entry area of the coupling element.

Abstract: The various implementations described herein include a video camera assembly that includes: (1) a housing; (2) an image sensor encased in the housing and configured to capture activity of the smart home environment; (3) a wireless radio configured to transmit video frames captured by the image sensor to an electronic device via a remote server; (4) at least one infrared transmitter configured to selectively illuminate the smart home environment; (5) one or more circuit boards encased in the housing, the one or more circuit boards including at least one processor mounted thereon; and (6) a heating component coupled to the image sensor, the heating component configured to continuously maintain the image sensor at a temperature above a threshold temperature while the image sensor is capturing the activity of the smart home environment.

Abstract: The various implementations described herein include a video camera assembly that includes: (1) a housing; (2) an image sensor positioned within the housing and having a field of view corresponding to a scene in the smart home environment; and (3) a concave-shaped front face positioned in front of the image sensor such that light from the scene passes through the front face prior to entering the image sensor; where the front face includes: (a) an inner section corresponding to the image sensor; and (b) an outer section between the housing and the inner section, the outer section having a concave shape that extends from an outer periphery of the outer section to an inner periphery of the outer section; and where the concave shape extends around an entirety of the outer periphery.

Abstract: A coupling device for a towing vehicle with an object detection device attached to the coupling device, wherein the coupling device has a coupling body in form of a fifth wheel plate and a locking mechanism, with which a coupling device in form of a kingpin is releasably held on the coupling body in its end position (E), wherein the coupling body includes an available space which is limited by a coupling device guiding contour and extends along a longitudinal axis (x), wherein the coupling device is at least partially immersed during coupling into the available space until reaching an end position (E).

Abstract: A fifth wheel coupling with a camera, including a coupling plate and a bearing element, with which the coupling plate can be secured to a towing vehicle, wherein the coupling plate has a centrally arranged locking region for receiving a king pin, as well as an insertion opening running along a longitudinal axis (x) and bordered on both sides by two insertion flanges. The camera is mounted in a position in the region of the fifth wheel coupling with the lowest possible risk of soiling and damage, with the camera being secured to the bearing element.

Abstract: A fifth wheel coupling including a coupling plate and a camera, wherein the coupling plate is supported on a towing vehicle by bearing elements, a centrally arranged locking region for receiving a king pin, a support surface at least partially laterally surrounding the locking region for supporting a trailer, as well as an insertion opening running radially from the locking region, which is bordered in a conically widened section on both sides by insertion flanges. The camera is mounted in a position in the region of the fifth wheel coupling with the lowest possible risk of soiling and damage, with the camera being arranged on one of the insertion flanges.

Abstract: Systems, devices, and methods for providing a sheet product dispenser with automated product level tracking functionality are provided herein. Various product level sensors are disclosed herein including a product level sensor configured to emit a signal toward an outer circumference of a sheet product roll on a spindle extending along a longitudinal axis and to receive a reflected signal. The product level sensor is positioned a radial distance away from the spindle and aimed to emit the signal in a direction that is not parallel and not perpendicular to the longitudinal axis. The product level sensor detects a parameter of the reflected signal corresponding to the distance between the product level sensor and the sheet product roll. Other example embodiments include mechanical product level sensors. Various communication protocols may be employed to limit transmission of data to conserve battery life while still maintaining desired communication functionality.

Abstract: A fifth wheel coupling including a coupling plate and a camera, wherein the coupling plate is supported on a towing vehicle by bearing elements, a centrally arranged locking region for receiving a king pin, a support surface at least partially laterally surrounding the locking region for supporting a trailer, as well as an insertion opening running radially from the locking region, which is bordered in a conically widened section on both sides by insertion flanges. The camera is mounted in a position in the region of the fifth wheel coupling with the lowest possible risk of soiling and damage, with the camera being arranged on one of the insertion flanges.

Abstract: A fifth wheel coupling with a camera, including a coupling plate and a bearing element, with which the coupling plate can be secured to a towing vehicle, wherein the coupling plate has a centrally arranged locking region for receiving a king pin, as well as an insertion opening running along a longitudinal axis (x) and bordered on both sides by two insertion flanges. The camera is mounted in a position in the region of the fifth wheel coupling with the lowest possible risk of soiling and damage, with the camera being secured to the bearing element.

Abstract: A method for moving a vehicle to a component of an object at a distance therefrom, the vehicle having a navigation module which has a camera and an evaluation electronics, and an identification element is attached to the object in a predetermined position in such a way that it is recognized by the camera in a far range (Dmax) of the vehicle from the object, and a reverse driving line of the vehicle is calculated by the evaluation electronics from the perspective position of the camera in relation to the identification element. The method improves the approach of a vehicle to a stationary object. A close-range (Dmin) is defined in the direction of the object by a close-range radius (Rmin) and the reverse driving line is calculated up to a virtual pre-positioning point (SVi, SVii, SViii) lying on the close-range radius (Rmin).

Abstract: A method for moving a vehicle to a component of an object at a distance therefrom, the vehicle having a navigation module which has a camera and an evaluation electronics, and an identification element is attached to the object in a predetermined position in such a way that it is recognized by the camera in a far range (Dmax) of the vehicle from the object, and a reverse driving line of the vehicle is calculated by the evaluation electronics from the perspective position of the camera in relation to the identification element. The method improves the approach of a vehicle to a stationary object. In a start position (S) of the vehicle, the navigation module generates a static object coordinate system (KO) and a reverse driving line is calculated from the start position (S) to a pre-positioning point (SVi, SVii, SViii).

Abstract: Systems, devices, and methods for providing a sheet product dispenser with automated product level tracking functionality are provided herein. Various product level sensors are disclosed herein including a product level sensor configured to emit a signal toward an outer circumference of a sheet product roll on a spindle extending along a longitudinal axis and to receive a reflected signal. The product level sensor is positioned a radial distance away from the spindle and aimed to emit the signal in a direction that is not parallel and not perpendicular to the longitudinal axis. The product level sensor detects a parameter of the reflected signal corresponding to the distance between the product level sensor and the sheet product roll. Other example embodiments include mechanical product level sensors. Various communication protocols may be employed to limit transmission of data to conserve battery life while still maintaining desired communication functionality.

Abstract: An interactive mobile robot system and a method for creating an invisible track for a mobile robot. The system and method allow the creation of invisible tracks by guiding objects. They also allow the use of such invisible tracks for the semi-autonomous or autonomous control of toys, including model cars and model trains, or of mobile robots to move them along a real-world path. The system includes a mobile robot, receiver circuitry to receive one or more position signals, and processing circuitry. The processing circuitry is configured to determine position information associated with the mobile robot based on the one or more position signals. The processing circuitry is further configured to create an invisible track based on the position information, to determine a current position of the mobile robot, and to generate control signals based on the current position of the mobile robot and the invisible track.

Abstract: Technical challenges of efficiently and cost-effectively deriving energy from the sun are addressed using a manifold and an array of evacuated tubes in fluid connection, in a butterfly or other planar arrangement. Tube and manifold fluid guides are plumbed for coaxial flow and/or parallel flow, and thermally protected by sleeves, stainless steel piping, and/or vacuum. Tubes are provided with a selective low emissivity coating and/or internal mirror to reduce thermal loss. The solar absorption surface of evacuated tubes may be five square meters or more, with only low-quality concentration optics, or no concentration optics used. The tubes array tracks the sun with a two-axis motion platform. Fluid operating temperatures range from 150 to 300 degrees centigrade, depending on the sunlight exposure, working fluid, and supplemental heat source if any. Fluid may circulate heat between the manifold and heat engine, cogeneration facility, and/or other module.

Abstract: Technical challenges of efficiently and cost-effectively deriving energy from the sun are addressed using a manifold and an array of evacuated tubes in fluid connection, in a butterfly or other planar arrangement. Tube and manifold fluid guides are plumbed for coaxial flow and/or parallel flow, and thermally protected by sleeves, stainless steel piping, and/or vacuum. Tubes are provided with a selective low emissivity coating and/or internal mirror to reduce thermal loss. The solar absorption surface of evacuated tubes may be five square meters or more, with only low-quality concentration optics, or no concentration optics used. The tubes array tracks the sun with a two-axis motion platform. Fluid operating temperatures range from 150 to 300 degrees centigrade, depending on the sunlight exposure, working fluid, and supplemental heat source if any. Fluid may circulate heat between the manifold and heat engine, cogeneration facility, and/or other module.

Abstract: A method includes determining, at a communication device, a designation of a source communication device based on information related to a communication from the source communication device. The method further includes selecting, at the communication device and based on the designation, a prompt from multiple prompts. The prompt includes a first prompt in response to the designation being a first designation of multiple designations. The prompt includes a second prompt in response to the designation being a second designation of the multiple designations. The method includes sending the prompt from the communication device to the source communication device.

Abstract: Technical challenges of efficiently and cost-effectively deriving energy from the sun are addressed using a manifold and an array of evacuated tubes in fluid connection, in a butterfly or other planar arrangement. Tube and manifold fluid guides are plumbed for coaxial flow and/or parallel flow, and thermally protected by sleeves, stainless steel piping, and/or vacuum. Tubes are provided with a selective low emissivity coating and/or internal mirror to reduce thermal loss. The solar absorption surface of evacuated tubes may be five square meters or more, with only low-quality concentration optics, or no concentration optics used. The tubes array tracks the sun with a two-axis motion platform. Fluid operating temperatures range from 150 to 300 degrees centigrade, depending on the sunlight exposure, working fluid, and supplemental heat source if any. Fluid may circulate heat between the manifold and heat engine, cogeneration facility, and/or other module.

Abstract: An interactive mobile robot system and a method for creating an invisible track for a mobile robot. The system and method allow the creation of invisible tracks by guiding objects. They also allow the use of such invisible tracks for the semi-autonomous or autonomous control of toys, including model cars and model trains, or of mobile robots to move them along a real-world path. The system includes a mobile robot, receiver circuitry to receive one or more position signals, and processing circuitry. The processing circuitry is configured to determine position information associated with the mobile robot based on the one or more position signals. The processing circuitry is further configured to create an invisible track based on the position information, to determine a current position of the mobile robot, and to generate control signals based on the current position of the mobile robot and the invisible track.