Abstract: Provided herein are novel heterocyclic compounds, for example, compounds having Formula I, I-P, II, II-P, III, or IV. Also provided herein are pharmaceutical compositions comprising the compounds and methods of using the same, for example, in inhibiting aldehyde dehydrogenases, retinoid pathway activation, and/or for treating various cancers, cancer metastasis, type 2 diabetes, pulmonary arterial hypertension (PAH) or neointimal hyperplasia (NIH) or as a male contraceptive.

Abstract: A system and method for manufacturing a memorial. The method providing a blank pattern in a memorial design and collaboration system having a specified shape and size and building a memorial preview thereon, then sending the memorial preview to a host computer. The host computer routes the memorial preview as a stored file to a manufacturer for projecting, onto a three-dimensional solid in the shape of said blank pattern, an image of said memorial preview. The method further includes creating a pattern by placing objects in the form of letters, emblems or numbers on the three-dimensional solid in connection with the projection, and creating a mold in connection with the pattern, and filling said mold and baking the filled mold.

Abstract: A system and method for manufacturing a memorial. The method providing a blank pattern in a memorial design and collaboration system having a specified shape and size and building a memorial preview thereon, then sending the memorial preview to a host computer. The host computer routes the memorial preview as a stored file to a manufacturer for projecting, onto a three-dimensional solid in the shape of said blank pattern, an image of said memorial preview. The method further includes creating a pattern by placing objects in the form of letters, emblems or numbers on the three-dimensional solid in connection with the projection, and creating a mold in connection with the pattern, and filling said mold and baking the filled mold.