Abstract: Assessing Susceptibility to Epilepsy and Epileptic Seizures A method and system adapted to assist with assessing susceptibility to epilepsy and/or epileptic seizures in a patient receives (202) patient brain data and generates (204) a network model from the received patient brain data. The system further generates (206) synthetic brain activity data in at least some of the nodes of the network model and computes (208) seizure frequency from the synthetic brain activity data by monitoring transitions from non-seizure states to seizures states in at least some of the nodes over time. The system further includes a device (104, 110) configured to use the seizure frequency to compute (210) a likelihood of susceptibility to epilepsy and/or epileptic seizures in the patient, and a device (104, 110) configured to compare (212) the computed likelihood with another likelihood of susceptibility to epilepsy and/or epileptic seizures in order to assess whether the likelihood has increased or decreased.

Abstract: A negative pressure wound closure devices, systems and methods. Embodiments of the invention facilitate closure of the wound by preferentially contracting under negative pressure to provide for movement of the surrounding tissues. Some embodiments may utilize a stabilizing structure with a plurality of cells configured to collapses more in the x-direction than in the y-direction.

Abstract: A headgear, for use in combination with a breathing apparatus, has a plastic or elastomer core and a fabric or textile casing. The headgear, or portions thereof, may also include a length adjustment arrangement that permits adjustment of a length of a section of the headgear. The length adjustment arrangement can comprise overlapping strap portions of the headgear. In some configurations, the overlapping strap portions can be covered by a sleeve. The sleeve can be secured to the headgear by overmolded end caps. A nasal respiratory interface can include a frame having a front surface, a rear surface, and an aperture extending from the front surface to the rear surface. The frame can have an oval form with a truncated height portion. The interface can also include a seal for a nasal pillow. The seal can be attached to the frame.

Abstract: Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular device is a guide wire having a core wire formed of multiple materials. For example, a sensing guide wire is provided that includes a core member having an inner section and an outer section surrounding the inner section, wherein the inner section is formed of a first material and the outer section is formed of a second material that is different than the first material; and a sensing element coupled to a distal portion of the core member. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided.

Abstract: A transcription engine transcribes input received from an augmented reality keyboard based on a sequence of hand poses performed by a user when typing. A hand pose generator analyzes video of the user typing to generate the sequence of hand poses. The transcription engine implements a set of transcription models to generate a series of keystrokes based on the sequence of hand poses. Each keystroke in the series may correspond to one or more hand poses in the sequence of hand poses. The transcription engine monitors the behavior of the user and selects between transcription models depending on the attention level of the user. The transcription engine may select a first transcription model when the user types in a focused manner and then select a second transcription model when the user types in a less focused, conversational manner.

Abstract: The present invention relates to a negative pressure wound closure system and methods for using such a system. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Preferred embodiments can utilize tissue grasping elements to apply a wound closing force to the tissue.

Abstract: An interface assembly comprises a nasal mask that includes a seal having a rolling portion. The rolling portion of the seal rolls over a portion of a clip that secures the seal to a frame. The frame has a ball and socket connection to a connector. The connector comprises an elbow having integrally formed exhaust holes and a swivel.

Abstract: A negative pressure wound closure system and methods for using such a system are described. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Some embodiments may utilize a stabilizing structure with removable sections.

Abstract: Methods and apparatuses are disclosed relating to the creation and use of bespoke wound fillers and other wound treatment apparatuses. Some embodiments provide for the creation of bespoke wound fillers based on characteristics of a wound. Certain embodiments also include the use of bespoke wound fillers in combination with negative pressure to treat a wound.

Abstract: Methods and apparatuses are disclosed relating to the creation and use of bespoke wound fillers and other wound treatment apparatuses. Some embodiments provide for the creation of bespoke wound fillers based on characteristics of a wound. Certain embodiments also include the use of bespoke wound fillers in combination with negative pressure to treat a wound.

Abstract: Disclosed herein are devices, wound dressings and methods for determining the pH of fluid or a wound exudate at a wound. Example devices include a device comprising a surface configured to contact the fluid or wound and a pH indicator covalently bound thereto or applied to the surface, wherein the pH indicator has a first colour prior to contact with the fluid or the wound exudate and changes colour as a function of the pH of the fluid or wound exudate. Example devices include a device which indicates wound exudate loading within a wound dressing and wound dressing comprising an absorbent layer and a moisture indicator which indicates would exudate loading within the dressing, wherein the visibility of the moisture indictor changes as a result of a physical transformation of a first material within the dressing. Systems, devices, and methods are provided for monitoring wound status and progression by measuring pH levels indicated by pH-sensitive wound dressings.

Abstract: Intravascular devices, systems, and methods are disclosed. In some embodiments, side-loading electrical connectors for use with intravascular devices are provided. The side-loading electrical connector has at least one electrical contact configured to interface with an electrical connector of the intravascular device. A first connection piece of the side-loading electrical connector is movable relative to a second connection piece such that in an open position an elongated opening is formed between the first and second connection pieces to facilitate side-loading of the intravascular device into the connector and in the closed position the at least one electrical contact is electrically coupled to the at least one electrical connector of the intravascular device received between the first and second connection pieces and a communication cable extends from the connector in a direction coaxial with or parallel to the longitudinal axis of the intravascular device.

Abstract: A respiratory mask system comprising a mask interface comprising a frame for a headgear assembly. The frame comprises a body comprising a first surface and a substantially opposing second surface. The body further comprises a gas inlet and optionally an outlet vent. The gas inlet may be substantially elliptical in shape. The frame may comprise a recessed region for receiving yoke of a headgear assembly to attach the headgear to the mask interface. The respiratory mask system may also comprise a yoke for attaching to the frame.

Abstract: A patient interface can have a frame supporting a sealing member. Various features of the sealing member can improve comfort and sealing performance in the context of forming seals with the nares of a user, as well as contact with other facial surfaces. The sealing member can include convex portions, concave portions and thickness variations for providing various sealing, comfort, and deformability effects.

Abstract: This disclosure an improved progressive shell reloader machine with improved components to reduce friction and jarring, thereby reducing powder losses during the reloading process, components including a smooth ring indexer, a gripping shellplate, and an antifriction camming pin. Additional improved components allow easy halting of primer and shell casing feed, facilitating troubleshooting, components including a positionable and reversible case insert slide block and a slide back primer cam.

Abstract: The present invention relates to a negative pressure wound closure system and methods for using such a system. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Preferred embodiments can utilize tissue grasping elements to apply a wound closing force to the tissue.

Abstract: Methods and apparatuses are disclosed relating to the creation and use of bespoke wound fillers and other wound treatment apparatuses. Some embodiments provide for the creation of bespoke wound fillers based on characteristics of a wound. Certain embodiments also include the use of bespoke wound fillers in combination with negative pressure to treat a wound.

Abstract: Methods and apparatuses are disclosed relating to the creation and use of bespoke wound fillers and other wound treatment apparatuses. Some embodiments provide for the creation of bespoke wound fillers based on characteristics of a wound. Certain embodiments also include the use of bespoke wound fillers in combination with negative pressure to treat a wound.