Abstract: The present invention relates to novel derivatives of cystobactamides of formula (Ib) and the use thereof for the treatment or prophylaxis of bacterial infections.

Abstract: Computed tomography (CT) measurement data of the patient is acquired using a CT device having a quantum counting X-ray detector, and the CT measurement data is processed to generate result data, considering a specific information content of the CT measurement data resulting from the use of the quantum counting X-ray detector in acquiring the CT measurement data. The result data is suitable for use in the planning of irradiation of the patient. The result data is provisioned to an interface such that the result data is usable for planning the irradiation of the patient.

Abstract: Techniques for a quantum device with modular quantum building blocks are provided. In one embodiment, a device is provided that comprises a substrate that is coupled with a plurality of qubit pockets, where at least one qubit pocket of the plurality of qubit pockets is coupled with a qubit. In one implementation, the device can further comprise a plurality of connectors coupled to the substrate and positioned around at least a portion of the substrate, where the plurality of connectors comprising a connecting element. In one or more implementations, the device can further comprise a plurality of transmission lines formed on the substrate and connect at least one connector of the plurality of connectors to at least one qubit pocket of the plurality of qubit pockets.

Abstract: Provided are antibodies that specifically bind to CTLA-4 and/or PD-1 and antagonize CTLA-4 and/or PD-1 function. Also provided are pharmaceutical compositions and kits comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies either alone or in combination.

Abstract: An arthroscopic shaver cleaning device and method of cleaning an arthroscopic shaver blade/burr are disclosed. The arthroscopic shaver cleaning device includes a sleeve portion configured to interface with a proximal portion of a blade/burr of an arthroscopic shaver. The arthroscopic shaver cleaning device further includes a fluid connection portion having a fluid passageway configured to direct fluid toward the proximal portion of the blade/burr in order to dislodge debris entrapped in shaver lumen of the blade/burr.

Abstract: The disclosure relates to a remote displacement sensor, such as an optical strain gauge, which uses an optical amplifier implemented by patterns, such as, moiré patterns, to calculate changes in position. In a strain gauge with moiré patterns, two foil layers are provided, a lower foil layer with a reference or static moiré pattern generated by the overlaying of a first pattern with parallel lines at a first fundamental frequency and a second pattern with parallel lines at a second fundamental frequency. The lower foil layer further includes a first section with a first pattern with parallel lines at the first fundamental frequency while the upper layer provides a second section with a second pattern with parallel lines at the second fundamental frequency. The overlaying of the foils causes an overlying of the first and second sections thereby causing a moiré pattern of the same wavelength as the reference pattern.

Abstract: The disclosure relates to a remote displacement sensor, such as an optical strain gauge, which uses an optical amplifier implemented by patterns, such as, but not limited to, moiré patterns, to calculate changes in position or gauge length. In the embodiment implemented as a strain gauge with moiré patterns, two foil layers are provided, a lower foil layer with a reference or static moiré pattern generated by the overlaying of a first pattern with parallel lines at a first fundamental frequency and a second pattern with parallel lines at a second fundamental frequency. The lower foil layer further includes a first section with a first pattern with parallel lines at the first fundamental frequency while the upper layer provides a second section with a second pattern with parallel lines at the second fundamental frequency. The overlaying of the foils causes an overlying of the first and second sections thereby causing a moiré pattern of the same wavelength as the reference pattern.

Abstract: A design structure for a 3D chip having at least one I/O layer connected to other 3D chip layers by a vertical bus such that the I/O layer(s) may accommodate protection and off-chip device drive circuits, customization circuits, translation circuits, conversions circuits and/or built-in self-test circuits capable of comprehensive chip or wafer level testing wherein the I/O layers function as a testhead. Substitution of I/O circuits or structures may be performed using E-fuses or the like responsive to such testing.

Abstract: An RF device includes a signal layer disposed over a ground plane having radio frequency (RF) transmission lines configured and dimensioned to provide impedance matching along the RF lines. A shield is formed as a part of the RF lines and disposed below the RF choke of a DC current supply to form an intermediate capacitance between the choke and the shield to control parasitic effects.

Abstract: A 3D chip having at least one I/O layer connected to other 3D chip layers by a vertical bus such that the I/O layer(s) may accommodate protection and off-chip device drive circuits, customization circuits, translation circuits, conversions circuits and/or built-in self-test circuits capable of comprehensive chip or wafer level testing wherein the I/O layers function as a testhead. Substitution of I/O circuits or structures may be performed using E-fuses or the like responsive to such testing.

Abstract: Techniques are disclosed for minimizing the effects of soft errors associated with memory devices that are individually accessible. By way of example, a method of organizing a column in a memory array of a memory device protected by an error correction code comprises the step of maximizing a distance of the error correction code by maximizing a physical distance between memory bits associated with a memory line within the column protected by the error correction code. Other soft error protection techniques may include use of a feed forward error correction code or use of a memory operation (e.g., read or write operation) suppress and retry approach.

Abstract: An RF device includes a signal layer disposed over a ground plane having radio frequency (RF) transmission lines configured and dimensioned to provide impedance matching along the RF lines. A shield is formed as a part of the RF lines and disposed below the RF choke of a DC current supply to form an intermediate capacitance between the choke and the shield to control parasitic effects.

Abstract: A collator includes a first conveyor having a discharge end and a second receiving conveyor positioned below the discharge end of the first conveyor. As each product bag falls toward the second conveyor, an air blast assists in uprighting the bag. The second conveyor may be temporarily operated at a high speed to separate the product bags into groups. A deflector may be mounted at the discharge end of the second conveyor for directing product bags into containers. A diverter may be used to direct incoming product bags between parallel conveyors.

Abstract: A collator includes a first conveyor having a discharge end and a second receiving conveyor positioned below the discharge end of the first conveyor. As each product bag falls toward the second conveyor, an air blast assists in uprighting the bag. The second conveyor may be temporarily operated at a high speed to separate the product bags into groups. A deflector may be mounted at the discharge end of the second conveyor for directing product bags into containers. A diverter may be used to direct incoming product bags between parallel conveyors.

Abstract: A collator includes a first conveyor having a discharge end and a second receiving conveyor positioned below the discharge end of the first conveyor. As each product bag falls toward the second conveyor, an air blast assists in uprighting the bag. The second conveyor may be temporarily operated at a high speed to separate the product bags into groups. A deflector may be mounted at the discharge end of the second conveyor for directing product bags into containers. A diverter may be used to direct incoming product bags between parallel conveyors.

Abstract: A collator includes a first conveyor having a discharge end and a second receiving conveyor positioned below the discharge end of the first conveyor. As each product bag falls toward the second conveyor, an air blast assists in uprighting the bag. The second conveyor may be temporarily operated at a high speed to separate the product bags into groups. A deflector may be mounted at the discharge end of the second conveyor for directing product bags into containers. A diverter may be used to direct incoming product bags between parallel conveyors.

Abstract: A collator includes a first conveyor having a discharge end and a second receiving conveyor positioned below the discharge end of the first conveyor. As each product bag falls toward the second conveyor, an air blast assists in uprighting the bag. The second conveyor may be temporarily operated at a high speed to separate the product bags into groups. A deflector may be mounted at the discharge end of the second conveyor for directing product bags into containers. Chutes may be used to direct incoming product bags between parallel conveyors.

Abstract: A collator includes a first conveyor having a discharge end and a second receiving conveyor positioned below the discharge end of the first conveyor. As each product bag falls toward the second conveyor, an air blast assists in uprighting the bag. The second conveyor may be temporarily operated at a high speed to separate the product bags into groups. A deflector may be mounted at the discharge end of the second conveyor for directing product bags into containers.

Abstract: A collator includes a first conveyor having a rotatable drum positioned at its discharge end. The rotatable drum is comprised of a plurality of disks. Two pairs of air nozzles are positioned between the rotating disks of the rotatable drum. A second receiving conveyor is positioned below the discharge end of the first conveyor. Bagged products move along the first conveyor and are discharged over the rotating drum of the first conveyor. As each product bag falls toward the second conveyor, an air blast assists in uprighting the bag. A sensor indicates that the product bag is properly positioned for uprighting by the air blast. A programmable logic controller ("PLC") which controls the operation of the collator in accordance with the size of the product bags.