Abstract: An internal combustion engine controller comprising a memory and a processor is provided. The memory is configured to store a plurality of control maps, each control map defining a hypersurface of actuator setpoints for controlling an actuator of the internal combustion engine based on a plurality of input variables to the internal combustion engine controller. The processor comprises an engine setpoint module and a map updating module. The engine setpoint module is configured to output a control signal to each actuator based on a location on the hypersurface of the respective control map defined by the plurality of input variables. The map updating module is configured to calculate an optimised hypersurface for at least one of the control maps. The optimised hypersurface is calculated based on a real-time performance model of the internal combustion engine comprising sensor data from the internal combustion engine and the plurality of input variables.

Abstract: Disclosed adjustable retaining arm systems can include a multi-segmented, articulable arm that holds one or more interchangeable tools and can be made relaxed to set a desired position and made rigid to fix the desired position by adjusting tension in a cable running through the arm. The arm can quickly attach and detach from a support structure. The support structure include a cable tensioning system, sensors, control system, power system, etc. A user input device, such as a foot pedal or button on the arm, can be used by a surgeon to change the arm between relaxed and rigid states. The arm and attachable tools can be detachable, disposable and/or sterilizable, while other system components can remain mounted in a fixed location as the arm is removed and replaced. The arm can hold multiple tools in any desired orientation around subject work location.

Abstract: Disclosed adjustable retaining arm systems can include a multi-segmented, articulable arm that holds one or more interchangeable tools and can be made relaxed to set a desired position and made rigid to fix the desired position by adjusting tension in a cable running through the arm. The arm can quickly attach and detach from a support structure. The support structure include a cable tensioning system, sensors, control system, power system, etc. A user input device, such as a foot pedal or button on the arm, can be used by a surgeon to change the arm between relaxed and rigid states. The arm and attachable tools can be detachable, disposable and/or sterilizable, while other system components can remain mounted in a fixed location as the arm is removed and replaced. The arm can hold multiple tools in any desired orientation around subject work location.

Abstract: An internal combustion engine controller comprising a memory and a processor is provided. The memory is configured to store a plurality of control maps, each control map defining a hypersurface of actuator setpoints for controlling an actuator of the internal combustion engine based on a plurality of input variables to the internal combustion engine controller. The processor comprises an engine setpoint module and a map updating module. The engine setpoint module is configured to output a control signal to each actuator based on a location on the hypersurface of the respective control map defined by the plurality of input variables. The map updating module is configured to calculate an optimised hypersurface for at least one of the control maps. The optimised hypersurface is calculated based on a real-time performance model of the internal combustion engine comprising sensor data from the internal combustion engine and the plurality of input variables.

Abstract: Disclosed adjustable retaining arm systems can include a multi-segmented, articulable arm that holds one or more interchangeable tools and can be made relaxed to set a desired position and made rigid to fix the desired position by adjusting tension in a cable running through the arm. The arm can quickly attach and detach from a support structure. The support structure include a cable tensioning system, sensors, control system, power system, etc. A user input device, such as a foot pedal or button on the arm, can be used by a surgeon to change the arm between relaxed and rigid states. The arm and attachable tools can be detachable, disposable and/or sterilizable, while other system components can remain mounted in a fixed location as the arm is removed and replaced. The arm can hold multiple tools in any desired orientation around subject work location.

Abstract: Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid encoding the xylose isomerase is an exogenous nucleic acid. Optionally, the recombinant microorganisms include at least one nucleic acid sequence encoding a xylulose kinase and/or at least one nucleic acid sequence encoding a xylose transporter. The provided recombinant microorganisms are capable of growing on xylose as a carbon source.

Abstract: Power system optimization calibration is disclosed.

Abstract: Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid encoding the xylose isomerase is an exogenous nucleic acid. Optionally, the recombinant microorganisms include at least one nucleic acid sequence encoding a xylulose kinase and/or at least one nucleic acid sequence encoding a xylose transporter. The provided recombinant microorganisms are capable of growing on xylose as a carbon source.

Abstract: Power system optimization calibration is disclosed.

Abstract: Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid encoding the xylose isomerase is an exogenous nucleic acid. Optionally, the recombinant microorganisms include at least one nucleic acid sequence encoding a xylulose kinase and/or at least one nucleic acid sequence encoding a xylose transporter. The provided recombinant microorganisms are capable of growing on xylose as a carbon source.

Abstract: Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid encoding the xylose isomerase is an exogenous nucleic acid. Optionally, the recombinant microorganisms include at least one nucleic acid sequence encoding a xylulose kinase and/or at least one nucleic acid sequence encoding a xylose transporter. The provided recombinant microorganisms are capable of growing on xylose as a carbon source.

Abstract: Provided are Thraustochytrid and Thraustochytrium and relevant methods and reagents, including engineered regulatory sequences and genes from and/or operative in Thraustochytrid or Thraustochytrium, selectable markers useful for engineering microorganisms such as Thraustochytrids, means for mutagenizing microorganisms, strains produced by mutagenesis, and methods and compositions related to production of particular compounds in microorganisms.

Abstract: Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid encoding the xylose isomerase is an exogenous nucleic acid. Optionally, the recombinant microorganisms include at least one nucleic acid sequence encoding a xylulose kinase and/or at least one nucleic acid sequence encoding a xylose transporter. The provided recombinant microorganisms are capable of growing on xylose as a carbon source.

Abstract: Provided are Thraustochytrid and Thraustochytrium and relevant methods and reagents, including engineered regulatory sequences and genes from and/or operative in Thraustochytrid or Thraustochytrium, selectable markers useful for engineering microorganisms such as Thraustochytrids, means for mutagenizing microorganisms, strains produced by mutagenesis, and methods and compositions related to production of particular compounds in microorganisms.

Abstract: A method is provided for compensating for factors affecting particulate matter accumulation within an aftertreatment element of an engine exhaust system. The method comprises determining rate of change of flow resistance through the aftertreatment element with time. Regeneration is periodically initiated to reduce particulate matter accumulation within the aftertreatment element. Rate of change of flow resistance through the aftertreatment element over time is correlated with at least a model of particulate matter accumulation within the aftertreatment element and a model of regeneration frequency of the aftertreatment element, based on predetermined values for particulate matter accumulation and regeneration frequency. Action, at least including increasing regeneration frequency, is initiated to compensate for an increased rate of particulate matter accumulation in the aftertreatment element.

Abstract: A method is provided for compensating for variability in ash accumulation rates within an aftertreatment element of an engine exhaust system. The method includes determining flow resistance values through the aftertreatment element and tracking minimum flow resistance values over time. The method also includes correlating the tracked minimum flow resistance values over time, with a model of engine oil consumption rate that is based on predetermined values for model engine oil consumption. The method further includes adjusting the predetermined values based on the tracked minimum flow resistance values over time.

Abstract: A method is provided for compensating for variability in ash accumulation rates within an aftertreatment element of an engine exhaust system. The method includes determining flow resistance values through the aftertreatment element and tracking minimum flow resistance values over time. The method also includes correlating the tracked minimum flow resistance values over time, with a model of engine oil consumption rate that is based on predetermined values for model engine oil consumption. The method further includes adjusting the predetermined values based on the tracked minimum flow resistance values over time.

Abstract: A method is provided for compensating for factors affecting particulate matter accumulation within an aftertreatment element of an engine exhaust system. The method comprises determining rate of change of flow resistance through the aftertreatment element with time. Regeneration is periodically initiated to reduce particulate matter accumulation within the aftertreatment element. Rate of change of flow resistance through the aftertreatment element over time is correlated with at least a model of particulate matter accumulation within the aftertreatment element and a model of regeneration frequency of the aftertreatment element, based on predetermined values for particulate matter accumulation and regeneration frequency. Action, at least including increasing regeneration frequency, is initiated to compensate for an increased rate of particulate matter accumulation in the aftertreatment element.