Patents by Inventor Mark A. Snyder

Mark A. Snyder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240142414
    Abstract: A dynamic axial compression column is disclosed herein. This dynamic axial column utilized external compression to prevent the creation of end plate space in the column. The dynamic axial column can include a tube defining a first opening, a second opening, and a lumen extending there between. The dynamic axial column can include a first end plate assembly sealing the first opening and movably extending at least partially into the lumen via the first opening, a second end plate assembly sealing the second opening, a plurality of rods extending along the outside of the tube and connecting the first end plate assembly and the second end plate assembly, and a first plurality of compression devices external to the tube and engaging one of the plurality of rods to bias the first end plate assembly towards the second end plate assembly.
    Type: Application
    Filed: October 25, 2023
    Publication date: May 2, 2024
    Inventors: Christopher BELISLE, Mark A. SNYDER
  • Patent number: 11841350
    Abstract: A dynamic axial compression column is disclosed herein. This dynamic axial column utilized external compression to prevent the creation of end plate space in the column. The dynamic axial column can include a tube defining a first opening, a second opening, and a lumen extending there between. The dynamic axial column can include a first end plate assembly sealing the first opening and movably extending at least partially into the lumen via the first opening, a second end plate assembly sealing the second opening, a plurality of rods extending along the outside of the tube and connecting the first end plate assembly and the second end plate assembly, and a first plurality of compression devices external to the tube and engaging one of the plurality of rods to bias the first end plate assembly towards the second end plate assembly.
    Type: Grant
    Filed: March 15, 2022
    Date of Patent: December 12, 2023
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Christopher Belisle, Mark A. Snyder
  • Publication number: 20220299486
    Abstract: A dynamic axial compression column is disclosed herein. This dynamic axial column utilized external compression to prevent the creation of end plate space in the column. The dynamic axial column can include a tube defining a first opening, a second opening, and a lumen extending there between. The dynamic axial column can include a first end plate assembly sealing the first opening and movably extending at least partially into the lumen via the first opening, a second end plate assembly sealing the second opening, a plurality of rods extending along the outside of the tube and connecting the first end plate assembly and the second end plate assembly, and a first plurality of compression devices external to the tube and engaging one of the plurality of rods to bias the first end plate assembly towards the second end plate assembly.
    Type: Application
    Filed: March 15, 2022
    Publication date: September 22, 2022
    Inventors: Christopher BELISLE, Mark A. SNYDER
  • Patent number: 10676502
    Abstract: The present invention discloses methods of neutralizing apatite surfaces, for example during chromatography and before protein elution.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: June 9, 2020
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Larry J. Cummings, Mark A. Snyder
  • Patent number: 10099157
    Abstract: Disclosed are compositions and methods for regenerating or reducing the deterioration of an apatite solid surface during, or subsequent to, a chromatographic procedure for purifying a target molecule from a sample, by treating the apatite solid surface with a buffered calcium solution, followed by a phosphate buffered solution, followed by an alkaline hydroxide. The buffered calcium solution, phosphate buffered solution, and alkaline hydroxide can be applied subsequent to a bind and elute or flow through purification procedure. The methods provide an increase in resin mass and/or particle strength compared to prior methods.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: October 16, 2018
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Mark A. Snyder, Kimberly C. Brisack
  • Publication number: 20180155390
    Abstract: The present invention discloses methods of neutralizing apatite surfaces, for example during chromatography and before protein elution.
    Type: Application
    Filed: January 24, 2018
    Publication date: June 7, 2018
    Inventors: Larry J. Cummings, Mark A. Snyder
  • Patent number: 9914749
    Abstract: The present invention discloses methods of neutralizing apatite surfaces, for example during chromatography and before protein elution.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: March 13, 2018
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Larry J. Cummings, Mark A. Snyder
  • Publication number: 20160052961
    Abstract: The present invention discloses methods of neutralizing apatite surfaces, for example during chromatography and before protein elution.
    Type: Application
    Filed: November 4, 2015
    Publication date: February 25, 2016
    Inventors: Larry J. Cummings, Mark A. Snyder
  • Publication number: 20150367252
    Abstract: Disclosed herein are methods of regenerating apatite surfaces, for example after purification of a target analyte.
    Type: Application
    Filed: June 23, 2015
    Publication date: December 24, 2015
    Inventors: Mark A. Snyder, Kimberly C. Brisack
  • Patent number: 9212203
    Abstract: The present invention discloses methods of neutralizing apatite surfaces, for example during chromatography and before protein elution.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: December 15, 2015
    Assignee: BIO-RAD LABORATORIES, INC.
    Inventors: Larry J. Cummings, Mark A. Snyder
  • Publication number: 20150191505
    Abstract: The present invention discloses methods of neutralizing apatite surfaces, for example during chromatography and before protein elution.
    Type: Application
    Filed: January 16, 2015
    Publication date: July 9, 2015
    Inventors: Larry J. Cummings, Mark A. Snyder
  • Patent number: 8951807
    Abstract: The present invention discloses methods of neutralizing apatite surfaces, for example during chromatography and before protein elution.
    Type: Grant
    Filed: January 13, 2011
    Date of Patent: February 10, 2015
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Larry J. Cummings, Mark A. Snyder
  • Publication number: 20130284257
    Abstract: A dye-sensitized solar cell with internal microlens array includes an anodic electrode, a cathodic counter-electrode, and an electrolyte. The anodic electrode includes a porous nano-structured active metal oxide layer having a sensitizer dye adsorbed thereon. In one embodiment, a microlens array comprising a plurality of microlens elements is disposed between the electrodes, and preferably between a transparent substrate of the anodic electrode and active metal oxide layer for dispersing light incident on the substrate to the active oxide layer. In some embodiments, the microlens elements may be convex or concave in configuration. The microlens array improves solar conversion efficiency of the solar cell. A method for forming a microlens array is further provided.
    Type: Application
    Filed: December 30, 2010
    Publication date: October 31, 2013
    Applicant: Lehigh University
    Inventors: James Gilchrist, Mark A. Snyder, Pisist Kumnorkaew
  • Patent number: 8550675
    Abstract: An outside mirror lighting assembly (100) and method includes a housing (108) and a first glass panel (101) where one or more light-emitting devices (107) are positioned at an edge of the first glass panel (101). Light rays from the at least one light-emitting device (107) propagate within the glass panel for illuminating its outer periphery. Words, logos, or other indicia (125) may be also be illuminated by direct or indirect light emitted into an etched area of the glass. The mirror assembly supplies a soft illuminated glow around the outer periphery and/or the indicia for providing a unique and pleasing appearance to the user.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: October 8, 2013
    Assignee: Gentex Corporation
    Inventors: Edmund Fehn, David J. Cammenga, Richard T. Fish, Jr., Darin D. Tuttle, Mark A. Snyder
  • Patent number: 8503060
    Abstract: A vehicular mirror assembly (100) includes a first bezel (107) for housing an electrochromic (EC) glass element and a second bezel (109) for housing a spotter glass (111) element. A spotter glass heating element (113) is positioned behind the spotter glass element (111) for heating the spotter glass (111) above an ambient temperature.
    Type: Grant
    Filed: August 15, 2008
    Date of Patent: August 6, 2013
    Assignee: Gentex Corporation
    Inventors: Timothy J. Thomas, David J. Cammenga, Mark A. Snyder
  • Publication number: 20130003405
    Abstract: An outside mirror lighting assembly (100) and method includes a housing (108) and a first glass panel (101) where one or more light emitting devices (107) are positioned at an edge of the first glass panel (101). Light rays from the at least one light emitting device (107) propagate within the glass panel for illumining its outer periphery. Words, logos, or other indicia (125) may be also be illuminated by direct or indirect light emitted into an etched area of the glass. The mirror assembly supplies a soft illuminated glow around the outer periphery and/or the indicia for proving a unique and pleasing appearance to the user.
    Type: Application
    Filed: September 12, 2012
    Publication date: January 3, 2013
    Inventors: Edmund Fehn, David J. Cammenga, Richard T. Fish, JR., Darin D. Tuttle, Mark A. Snyder
  • Patent number: 8287164
    Abstract: An outside mirror lighting assembly (100) and method includes a housing (108) and a first glass panel (101) where one or more light emitting devices (107) are positioned at an edge of the first glass panel (101). Light rays from the at least one light emitting device (107) propagate within the glass panel for illumining its outer periphery. Words, logos, or other indicia (125) may be also be illuminated by direct or indirect light emitted into an etched area of the glass. The mirror assembly supplies a soft illuminated glow around the outer periphery and/or the indicia for proving a unique and pleasing appearance to the user.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: October 16, 2012
    Assignee: Gentex Corporation
    Inventors: Edmund Fehn, David J. Cammenga, Richard T. Fish, Jr., Darin D. Tuttle, Mark A. Snyder
  • Patent number: 8263035
    Abstract: In general, in one aspect, the invention features a method that includes preparing a mixture comprising water, a basic amino acid, and a metal oxide precursor under conditions which result in the formation of metal oxide nanoparticles from the metal oxide precursor.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: September 11, 2012
    Inventors: Tracy M. Davis, Mark A. Snyder, Michael Tsapatsis, J. Alex Lee
  • Patent number: 8258270
    Abstract: In an affinity-type purification, ligands dissociated from the stationary phase that would otherwise leach into the species being purified are captured by a second ligand that is also incorporated into the stationary phase, the second ligand exhibiting an affinity-type interaction with the dissociated first ligand with sufficient specificity to avoid the undesired retention by the second ligand of species from the liquid sample or source liquid other than the species sought to be purified in the affinity column.
    Type: Grant
    Filed: May 8, 2009
    Date of Patent: September 4, 2012
    Assignee: Bio-Rad Laboratories, Inc.
    Inventor: Mark A. Snyder
  • Publication number: 20120124810
    Abstract: In an axial-flow preparative chromatography column that contains a piston, commonly termed an adaptor, that is lowered over the top of the resin, the ability to lower the piston in a controlled manner to minimize the chances of damage to the resin is achieved by use of an aperture either in the piston head itself or in a compound bolt that secures the upper column frit to the piston head. The aperture is closed with a removable plug during storage and use of the piston head and column. During packing of the bed, however, the plug is replaced by a graduated rod operating as a dipstick to allow the operator to determine the distance between the bottom face of the piston head and the upper surface of the column packing.
    Type: Application
    Filed: January 31, 2012
    Publication date: May 24, 2012
    Applicant: BIO-RAD LABORATORIES, INC.
    Inventor: Mark A. SNYDER