Abstract: This disclosure includes methods and systems for producing ophthalmic lenses. Some methods include identifying a plurality of zones within a spatial representation of a lens blank, selecting, for each of the zones, one or more parameters for producing the lens, and producing the lens by removing material from the lens blank according to the one or more parameters of each of the zones.

Abstract: Systems and methods are disclosed for assessing cardiovascular disease and treatment effectiveness based on adipose tissue. One method includes identifying a vascular bed of interest in a patient's vasculature; receiving a medical image of the patient's identified vascular bed of interest; identifying adipose tissue in the received medical image; receiving a geometric vascular model comprising a representation of the patient's identified vascular bed of interest; and computing an inflammation index associated with the geometric vascular model, using the identified adipose tissue.

Abstract: A method includes: accessing objects, generated by a set of sources, representing attributes of assets, affiliated with a computer network, including a set of endpoint devices and a first application; partitioning the objects into object groups including a first object group representing the first application; aggregating objects in the first object group into a first user container representing the first application during the first time interval; and, in response to selection of the first application at an operator portal: generating a visualization representing a subset of endpoint devices, in the set of endpoint devices, on which the first application is installed during the first time interval based on a set of attributes, exhibited by the first application during the first time interval, contained in the first application container; and rendering the visualization at the operator interface.

Abstract: A method comprising retrieving a plurality of clinical trial records from a clinical trial database; mapping each of the plurality of clinical trial records to one or more of a plurality of payment records from a payment database, manifesting a set of mapped records; merging each of the plurality of clinical trial records with the one or more of the plurality of payment records based on the set of mapped records, forming a merged dataset comprising a plurality of merged data entries; estimating imputed enrollees for each of the merged data entries; determining a ranking for each of the one or more ranking factors for each of the merged data entries; determining a score for each of the merged data entries based on the rankings; and generating a visualizer based on at least the score for each of the merged data entries.

Abstract: An image-based approach for statistical shape and appearance modeling includes re-orienting (rotating/translating) training masks to align the training masks with a reference mask to provide corresponding re-orientation parameters, where the training masks represent 3-dimensional shapes of a population of objects and the reference mask represents a 3-dimensional shape of a reference object, deforming the re-oriented training masks based on the reference mask to provide displacement fields indicative of differences between a 3-dimensional shape of the reference mask and 3-dimensional shapes of the re-oriented training masks, re-orienting training backgrounds based on the re-orientation parameters, where the training backgrounds represent volumetric intensity data of the 3-dimensional images of the objects, deforming the re-oriented training backgrounds based on the displacement fields, combining the deformed training backgrounds and the displacement fields, and reducing a dimensionality of the combined deforme

Abstract: Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes.

Abstract: A stand-alone modular removable rudder system for watercraft having a rudder comprising a steering handle coupled to a quick release mechanism adapted to releasably secure said steering handle to said watercraft in proximity to the operator, said system further comprising, a rudder mount adapted to be coupled to the rear of the watercraft by a quick release mechanism adapted to releasably secure said rudder mount to said watercraft, said rudder being carried by a rudder support pivotal about said rudder mount and cables operatively connecting said steering handle to said rudder mount whereby the steering handle can be operated to steer the rudder.

Abstract: Content providers may wish to display different versions of content to different users, which may require different versions of the content to be deliverable. The assignment of a particular version of the content to a particular user may also need to persist over time for that particular user. It may be desirable that this functionality occurs at an edge server of a content delivery network, rather than at an origin server. In some embodiments, the edge server may receive a user request including a user identifier for content from a user device; identify an experiment key for the user request based at least in part on the user identifier, the experiment key associated with an experimental version of the content; and transmit an experiment fetch request including the experiment key to an edge cache to retrieve the experimental version of the content.

Abstract: A densitometer assembly comprises a pipe fabricated from a high-yield steel, a radioactive source, and a detector. The radioactive source is mounted on an exterior wall of the pipe and is adapted to emit gamma radiation in a defined beam. The detector is mounted on an opposing, facing exterior wall of the pipe in alignment with the gamma radiation beam and is adapted to detect gamma radiation.

Abstract: A method for generating a dual-class dataset is disclosed. A single-class dataset and a context dataset are obtained. The context dataset can be labeled. A model can be trained using the combination of the single-class dataset and the labeled context dataset. The model can be run on the context dataset. The data points that are classified the same as the data points included in the single-class dataset, can be removed from the labeled context dataset and added to the single-class dataset. These steps can be repeated until no data points are classified by the model.

Abstract: A method for real-time invoice updating and account-to-account payment includes: receiving invoice data based on presentation of an invoice by a distributor to a recipient at a delivery location, modification of the invoice by the recipient, and acceptance of the invoice by the recipient; generating a request for payment (RFP) message based on the invoice data; transmitting the RFP message to a financial institution associated with the recipient via a financial institution of the distributor; receiving, from the financial institution associated with the distributor, a payment confirmation for the invoice based on a real-time payment from the financial institution associated with the recipient; generating reconciliation data based on the payment confirmation and the invoice data; and transmitting the reconciliation data to a computing device of the distributor and a computing device of the recipient.

Abstract: Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes.

Abstract: A data organizer, optimizing, reconciliation system (DOORS)/method/program, provides capability to merge intuitively datasets created over users' digital lifetimes from multiple devices. Finds and gathers files from devices and may create master copies in Cloud or local storage. Enhanced functionality via artificial intelligence or machine learning provides more intuitive merging of datasets including file and folder name selection and may operate autonomously at times of low usage. Optimized by learning from training data, or legacy data, or learning in real time from user preferences, practices, and habits. Reducing loses of treasured photographs and important documents via preventing files getting marooned on inaccessible legacy devices. Because devices get lost, replaced, or may suffer ransomware attacks or may need to be re-set and suffer data loss for a variety of reasons.

Abstract: A cannulated retrograde reamer configured to be disposed over a guidewire that is adjustable to create tunnels of multiple different diameters. The cannulated retrograde reamer substantially reduces the risk of tunnel malposition and/or misalignment, and can be adjusted to create a range of tunnel diameters, thereby allowing inventory levels to be reduced for a surgical case.

Abstract: An attachment for a haircare appliance, the attachment including an air inlet, an air outlet. The attachment has a curved surface adjacent to and downstream of the air outlet. A radius of curvature of the curved is at least 16 mm. A haircare appliance having an air inlet, an air outlet, and an airflow generator for generating an airflow from the air inlet to the air outlet. The haircare appliance has a curved surface adjacent to and downstream of the air outlet. A radius of curvature of the curved surface is at least 16 mm.

Abstract: Provided herein is a composition including a compound having the structure: a pharmaceutically acceptable salt(s) thereof, and one or more excipients selected from (a)-(g): a) C2-6 alcohol; b) an organic solvent and/or a penetration enhancer; c) an antioxidant; d) a preservative; e) water; f) a pH adjuster; and g) a gelling agent, wherein C2-6 alcohol, the organic solvent and/or a penetration enhancer, the antioxidant, the preservative, water, the pH adjuster, and the gelling agent are defined and described herein. Methods of treating a skin disease, condition or disorder, in particular seborrheic keratosis, with the compositions are also provided herein.

Abstract: A haircare appliance has an air inlet, an air outlet, and an airflow generator for generating an airflow from the air inlet to the air outlet. The air outlet is at least partially defined by movable member. Movement of the movable member varies a cross-sectional area of the air outlet, and the movable member is movable in a radial direction relative to a central axis of the haircare appliance.

Abstract: System, method, and apparatus including receiving an identification of content played by a playback system and an identification of location of the playback system. A playlist of content is associated with the location. A request is received to retrieve the playlist of content and the requested playlist of content is sent to a playback system.

Abstract: Provided herein are compositions comprising ruboxistaurin free base and its salts thereof and methods of use for treating conditions of the skin.

Abstract: A bleach catalyst suitable for use in automatic dishwashing comprising a mixed metal oxide.