Patents by Inventor Mark A. Tepper

Mark A. Tepper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPOXIN A4 ANALOGS AND USES THEREOF
    Publication number: 20210401798
    Abstract: The invention relates to (S)-6-((1 R,2E,4E,8E,10S)-11-(4-fluorophenoxy)-1,10-dihydroxyundeca-2,4,8-trien-6-yn-1-yl)-1,4-dioxan-2-one (compound (1)), which is a lactone-containing analog of lipoxin A4 (LXA4). In particular, the invention features pharmaceutical compositions including compound (1) and the use of compound (1) for the treatment of a disorder (e.g., a fibrotic disorder or an inflammatory disorder, such as an autoimmune disorder) in a subject in need thereof.
    Type: Application
    Filed: October 23, 2019
    Publication date: December 30, 2021
    Applicants: The Brigham and Women's Hospital, Inc., Corbus Pharmaceuticals, Inc., Corbus Pharmaceuticals, Inc.
    Inventors: Nan CHIANG, Sheldon N. CRANE, Thomas JENNEQUIN, Valdas JURKAUSKAS, Clifton D. LEIGH, Kristos Adrian MOSHOS, Charles N. Serhan, Mark A. Tepper, Yuhua George Zhang
  • METHODS FOR THE TREATMENT OF INFECTION
    Publication number: 20200405687
    Abstract: The invention provides methods for treating an infection in a subject in need thereof by administering to the subject a pharmaceutical composition including ajulcmic acid, or a pharmaceutically acceptable salt thereof. In various embodiments, the infection may be a bacterial, viral, or fungal infection. The invention also features methods of treating an infection in a subject in need thereof by administering to the subject ajulemic acid, or a pharmaceutically acceptable salt thereof, and a suitable antibiotic, antifungal, or antiviral.
    Type: Application
    Filed: January 31, 2020
    Publication date: December 31, 2020
    Inventors: Mark A. TEPPER, Derek W. GILROY, Madhur MOTWANI, Tracey L. BONFIELD
  • METHODS FOR THE TREATMENT OF INFECTION
    Publication number: 20190133995
    Abstract: The invention provides methods for treating an infection in a subject in need thereof by administering to the subject a pharmaceutical composition including ajulemic acid, or a pharmaceutically acceptable salt thereof. In various embodiments, the infection may be a bacterial, viral, or fungal infection. The invention also features methods of treating an infection in a subject in need thereof by administering to the subject ajulemic acid, or a pharmaceutically acceptable salt thereof, and a suitable antibiotic, antifungal, or antiviral.
    Type: Application
    Filed: April 28, 2017
    Publication date: May 9, 2019
    Inventors: Mark A. TEPPER, Derek W. GILROY, Madhur MOTWANI, Tracey L. BONFIELD
  • Iontophoretic transdermal delivery of deoxyspergualin compounds
    Patent number: 5505715
    Abstract: A method and system is described for the noninvasive administration of a therapeutic concentration of a deoxyspergualin compound to a patient comprising iontophoretically passing the deoxyspergualin compound through an area of the skin of the patient at a flux effective to provide the therapeutic concentration.
    Type: Grant
    Filed: February 25, 1994
    Date of Patent: April 9, 1996
    Assignee: Bristol-Myers Squibb Company
    Inventors: Hemanshu S. Shah, Cheng-Der Yu, Mark A. Tepper, Bhiku Patel