Abstract: Animal restraint system for use in safely transporting non-caged animals, such as dogs, on a pickup truck bed. The system includes a four-point anchored arrangement of straps that facilitate a lengthwise symmetrical placement of the animal restraint system within the bed of a pickup truck. The system includes a plurality of anchor devices secured to the forward and rear corner areas of a truck bed, a first cross-strap arrangement, including a pair of adjustable length strap members mechanically joined at one end and having respective mechanical anchors at another end, and a second cross-strap arrangement, including a pair of fixed length strap members mechanically joined at one end and also having mechanical anchors at another end. Each mechanical anchor associated with each cross-strap arrangement being mechanically secured to the anchor devices at the forward and rear corner areas of the truck bed.