Abstract: Among other things, the present disclosure provides technologies for modulating complement activation. In some embodiments, the present disclosure provides compounds that inhibit C3 convertase activity. In some embodiments, the present disclosure provides methods for treating complement-mediated conditions, disorders or diseases. In some embodiments, the present disclosure provides methods for treating conditions, disorders or diseases mediated by C3 convertase.

Abstract: The invention enables digital music content to be downloaded to and used on a portable wireless computing device. An application running on the wireless device has been automatically adapted to parameters associated with the wireless device without end-user input (e.g. the application has been configured in dependence on the device OS and firmware, related bugs, screen size, pixel number, security models, connection handling, memory etc., This application enables an end-user to browse and search music content on a remote server using a wireless network; to download music content from that remote server using the wireless network and to playback and manage that downloaded music content. The application also includes a digital rights management system that enables unlimited legal downloads of different music tracks to the device and also enables any of those tracks stored on the device to be played so long as a subscription service has not terminated.

Abstract: A beverage production system is provided that includes a turntable assembly comprising a central axis. The turntable assembly further includes an inner turntable and an outer turntable disposed circumferentially about the inner turntable. The beverage production system also includes a cup dispensing station configured to dispense cups onto one of the inner or outer turntables. The beverage production system also includes a beverage dispensing station configured to dispense a beverage into the cups.

Abstract: A system filters near-duplicate images to generate data for training or validation of a machine learning model. The system receives a set of images and generates feature vectors from the images. The system clusters the feature vectors. For each cluster of feature vectors, the system determines near-duplicate pairs of images. The system may generate a cost matrix representing a linear assignment problem and find near-duplicate pairs of images by solving the linear assignment problem. The system filters images from the set of images based on the near-duplicate pairs of images. The system uses the filtered set of images for training or validation of the machine learning model.

Abstract: Systems, computer program products, and methods are described herein for detecting artificial intelligence (AI) masking using persistent response testing. The present invention is configured to identify a vocal request; generate a primary prompt associated with the vocal request; receive, based on the primary prompt, a primary vocal cue data; determine at least one primary vocal characteristic based the primary vocal cue data; generate at least one secondary prompt associated with the vocal request for at least one second period; receive, based on the at least one secondary prompt, at least one secondary vocal cue data; determine at least one secondary vocal characteristic based on the one secondary vocal cue data; compare the at least one primary vocal characteristic to the at least one secondary vocal characteristic; and determine, based on the comparison, whether the vocal request is based on artificial intelligence (AI).

Abstract: An irrigation nozzle is provided. The irrigation nozzle comprises a nozzle body forming a first body portion. The first body portion is generally cylindrical in shape and forms a nozzle cavity and at least one deflecting nozzle passage. Each deflecting nozzle passage extends from the nozzle cavity to an exterior surface of the first body portion. Each deflecting nozzle passage includes a deflector surface located adjacent to an exterior surface of the first body portion. The size and spatial orientation of each deflector surface and the curvature and hydraulic diameter of each deflecting nozzle passage upstream from each deflector surface are configured such that water flowing from the nozzle cavity through each deflecting nozzle passage impinges upon each deflector surface and spreads tangentially to a desired magnitude while flowing radially outward from said first body portion on a desired trajectory. The nozzle body is constructed as a unitary object.

Abstract: An electro-optic media includes either a plurality of microcapsules in a binder, a polymeric sheet containing sealed microcells, or droplets in a continuous polymeric phase. Each of the microcapsules, microcells, or droplets contain a dispersion that includes a plurality of charged composite particles and a suspending fluid, and the charged particles move through the suspending fluid under the influence of an electric field. The composite particles include one or more types of pigment particles that are at least partially coated with a polymeric material. Each of the binder, polymeric sheet, continuous polymeric phase, the charged composite particles, and the suspending fluid have an index of refraction, and a difference between the index of refraction of the composite particles and at least one of the binder, polymeric sheet, continuous polymeric phase, and solvent is less than or equal to 0.05 at 550 nm.

Abstract: The invention relates to a system for measuring real-time aerodynamic drag of a moving vehicle, for example, a bicycle and rider. The system comprises a processor and a non-transitory computer medium for storing data. Further, it comprises a single, compact, multi-port measurement system (MPMS) comprised of at least two differential pressure sensors electrically connected to the processor and the non-transitory computer-readable medium, wherein the processor is configured to convert a first differential air pressure from a first sensor to a wind speed, and to convert a second differential air pressure from a second sensor to a wind direction. The system further comprises a plurality of sensors for detecting forces, including barometric pressure, air temperature and relative humidity, distance, and speed, surrounding the moving vehicle. The plurality of sensors are electrically connected to the processor and the non-transitory computer-readable medium, and also store data.

Abstract: A table assembly comprising a table including a top member and at least a first leg support member, the top member forming a substantially flat top surface and circumscribed by an outer edge, the at least one leg support member supporting the top member in a substantially horizontal position, a table dock secured to the top member and forming an elongated channel having a dock length dimension and at least a first display panel circumscribed by a panel edge and having at least one straight edge having a panel length dimension, the dock length dimension less than panel length dimension, wherein at least a portion of the straight edge of the panel is receivable within the dock channel with the panel extending out the open first and second ends of the channel to support the panel in a substantially upright orientation with at least a portion of the display panel extending to a height above the flat top surface.

Abstract: A method of making a non-fibrous laundry detergent sheet can include dispensing a microcapsule onto a precursor non-fibrous laundry detergent sheet, wherein the precursor non-fibrous laundry detergent sheet can include: (a) at least one surfactant; (b) at least one film former; and (c) a thickness ranging from 0.1 mm to 10 mm.

Abstract: Disclosed are non-treated, creped tissue webs, and tissue products produced therefrom, having low stiffness and surface lint. The inventive products may be produced by a print creping process adapted to dispose a non-crosslinked latex polymer on at least one of the outer surfaces of the tissue product. The non-crosslinked latex polymer creping composition does not negatively affect stiffness such that the products generally have a Stiffness Index less than about 5.0, such as from about 2.5 to about 5.0.

Abstract: Surgical systems and methods for performing an osteotomy are disclosed herein. A surgical system includes a frame including a first section, second section, third section, fourth section, and a window. The surgical system can include a cut guide that can fit within the window and contact the first side, the second side, the third side, and the fourth side. The surgical system can include an aligner that can fit within the window and contact the first side, the second side, the third.

Abstract: Active agent-containing articles, for example fibrous structures, that exhibit consumer acceptable article in-use properties, such as flexibility, article dimensions, and/or dissolvability, and product-shipping assemblies for containing the same are provided.

Abstract: System and methods are disclosed for augmenting a synthesized NoC, with data that guides a physical implementation of the NoC topology in a way that coincides with the topology synthesis result and reduces timing violations in the final physical design. The system generates physical implementation guidance, which is during physical implementation of the synthesized NoC. The system inserts a link as a pipeline placeholder and a minimum set of created module regions are assigned to a specific link of the topology. Each route has a new link and corresponding module region inserted into the physical path.

Abstract: A stand-alone modular removable rudder system for watercraft having a rudder comprising a steering handle coupled to a quick release mechanism adapted to releasably secure said steering handle to said watercraft in proximity to the operator, said system further comprising, a rudder mount adapted to be coupled to the rear of the watercraft by a quick release mechanism adapted to releasably secure said rudder mount to said watercraft, said rudder being carried by a rudder support pivotal about said rudder mount and cables operatively connecting said steering handle to said rudder mount whereby the steering handle can be operated to steer the rudder.

Abstract: A circuit assembly may include a substrate and a pattern of contact points formed from deformable conductive material supported by the substrate. The assembly may further include an electric component supported by the substrate and having terminals arranged in a pattern corresponding to the pattern of contacts points. The one or more of the terminals of the electric component may contact one or more of the corresponding contact points to form one or more electrical connections between the electric component and the contact points.

Abstract: A system for calibrating a plurality of user sensors includes a calibration management system comprising a processor and a node services module and a plurality of calibration nodes disposed at a plurality of geographical locations. The processor is communicably coupled to the plurality of user sensors, the node services module, and the plurality of calibration nodes and operable to: provide calibration node information to a system associated with one of the plurality of user sensors and cause the calibration node to perform at least one calibration action after providing the calibration information, the calibration action may include performing an environmental measurement and/or providing a calibration reference signal to the user sensor. The processor is also operable to provide calibration results information containing results of the calibration action to the system associated with the one of the plurality of user sensors.

Abstract: Example apparatus disclosed herein are to generate first descriptive data of a first physical characteristic of a first object based on first camera sensor data from a first camera sensor, and generate second descriptive data of a second physical characteristic of a second object based on second camera sensor data from a second camera sensor different from the first camera sensor. Disclosed example apparatus are also identify, based on the first descriptive data and the second descriptive data, common physical characteristics associated with both the first object and the second object, first unique physical characteristics associated with the first object, and second unique physical characteristics associated with the second object. Disclosed example apparatus are further to identify the first object and the second object as one of a same object or different objects based on the common physical characteristics, the first unique physical characteristics, and the second unique physical characteristics.

Abstract: Disclosed herein is a pretreatment composition comprising a Group IVB metal in an amount of 200 ppm to 5.000 ppm based on total weight of the pretreatment composition, total fluoride in an amount of 1.000 ppm to 25.000 ppm based on total weight of the pretreatment composition and an electropositive metal. Also disclosed herein is a pretreatment composition comprising a Group IVB metal in an amount greater than 500 ppm based on total weight of the pretreatment composition and free fluoride in an amount of 50 ppm to 750 ppm based on total weight of the pretreatment composition, wherein the pretreatment composition has a pHI greater than 4. Also disclosed herein are systems and methods for treating a substrate. Also disclosed herein are treated substrates.

Abstract: A humidification system for delivering humidified gases to a user can include a heater base, humidification chamber having an inlet, outlet, and associated fluid conduit, and breathing circuit including a supply conduit, inspiratory conduit, and optional expiratory conduit. The humidification system can include various features to help make set-up less difficult and time-consuming. For example, the supply conduit, inspiratory conduit, and optional expiratory conduit can be coupled into a one-piece circuit to aid set-up. Various components can be color-coded and can have corresponding structures to indicate which components should be connected to one another during set-up. Such features can also help make the set-up process more intuitive for an operator, which can reduce the need for specialized training and reduce the number of potential errors.