Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) having core structure (I), pharmaceutical compositions containing at least one such modulator, methods of treatment of CFTR mediated diseases, including cystic fibrosis, using such modulators and pharmaceutical compositions, combination pharmaceutical compositions and combination therapies employing those modulators, and processes and intermediates for making such modulators.

Abstract: Methods are provided for a collaborative, decentralized insight engineering based on exchanging telemetry vectors with peer network devices. Each network device independently detects a deviation in its functioning using machine learning of generated feature vectors. Specifically, the methods involve obtaining, from at least one peer network device, at least a first feature vector that represents at least one insight generated from telemetry data of a respective peer network device. The intermediate network device and the at least one peer network device are configured to forward packets of a traffic flow. The methods further involve determining whether a deviation related to one or more of the network devices, exists based at least on the first feature vector and performing the at least one predefined action based on determining that the deviation exists.

Abstract: Automated cold storage unit and systems for storing, monitoring, and maintaining a supply of temperature sensitive pharmaceutical and/or other products in compliance with regulatory requirements are provided. Such units contain an array of independently addressable holding locations for containers with product in one or more controlled temperature zones fitted with temperature sensors. The units include a reader to track product information and status. Product movement within the unit is performed by a computer-controlled robot. A user interface device, preferably in communication with an application service provider to provide remotely managed inventory management and other services, provides users with secure access to the contents of the unit and associated product data and information.

Abstract: A system receives data from a submersible remote operated vehicle (ROV), the data being about the operation of an arm of the ROV. The system automatically controls, based on the data, movement of the arm in docking the arm to a tool holder. In certain instances, the system implements an image based control. In certain instances, the system implements a force accommodation control. In certain instances, the system implements both.

Abstract: The disclosure provides RFID labels including a composite label affixed to a surface of a container holding an object, including a first configuration wherein the first label section is positioned in the composite label and wherein the first label section can be removed from the composite label and configured to be affixed to the object.

Abstract: A mobility apparatus includes a frame, a body surrounding the frame having a front side, a rear side, a top side, a bottom side, and first and second lateral sides, a seat located on the top side of the body, a plurality of wheels attached to the frame, a motor for driving at least one of the plurality of wheels attached to the frame, a battery for supplying electricity to the motor, and a controller for directing movement of the mobility apparatus. The top side of the body includes seats for children to ride the mobility apparatus. The mobility apparatus may also include a tether cord or handrails for directing movement of the mobility apparatus, or the mobility apparatus may follow a transmitter or autonomously drive.

Abstract: One or more methods and/or techniques for coupon providing is provided herein. A user, of a client device, may search for an entity (e.g., a consumer product and/or service). The entity may be associated with a domain (e.g., a business that offers the entity for purchase). An advertisement associated with the entity and/or the domain may be identified. A coupon associated with the advertisement for the domain may be identified. The coupon may be applicable to the entity. The advertisement and the coupon may be provided on a webpage.

Abstract: A motor vehicle operator interface and control algorithm convey diesel particulate filter regeneration status to the operator. The algorithm also allows new control over heretofore automatic regeneration, through limiting the inhibit function. The DPF after-treatment operator interface provides multiple status indications to the operator. In a preferred embodiment this is effected using a switched indicator lamp.

Abstract: A motor vehicle operator interface and control algorithm convey diesel particulate filter regeneration status to the operator. The algorithm also allows new control over heretofore automatic regeneration, through limiting the inhibit function. The DPF after-treatment operator interface provides multiple status indications to the operator. In a preferred embodiment this is effected using a switched indicator lamp.

Abstract: A motor vehicle operator interface and control algorithm convey diesel particulate filter regeneration status to the operator. The algorithm also allows new control over heretofore automatic regeneration, through limiting the inhibit function. The DPF after-treatment operator interface provides multiple status indications to the operator. In a preferred embodiment this is effected using a switched indicator lamp.

Abstract: A universal water meter connector assembly that is configured to be used with different sized water meter couplers and a variety of dwelling supply lines. The universal water meter connector assembly includes a hexagonal hollow body that terminates in an externally threaded head at one end. The hexagonal body is provided with an internally threaded medial portion an end adjacent the head and an internally threaded end portion at the other end of the hexagonal body. The thread size of the medial portion is smaller than the thread size of the end portion to accommodate different sized water meter couplers. A internal stop is formed in the body below the head and above the medial portion for limiting movement of a supply line inserted into the body. The free end of the head is formed with an internally tapered portion that is configured to receive a cone-shaped member having a narrow end and a wide end with a beveled rim.

Abstract: A motor vehicle operator interface and control algorithm convey diesel particulate filter regeneration status to the operator. The algorithm also allows new control over heretofore automatic regeneration, through limiting the inhibit function. The DPF after-treatment operator interface provides multiple status indications to the operator. In a preferred embodiment this is effected using a switched indicator lamp.

Abstract: A multipurpose plumbing tool has a body at one end, a head at an opposite end and an intermediate neck portion connecting the body and head. The marginal end portion of the body is cut back to form a reduced section, a shoulder being formed at the junction of the reduced section and a non-reduced section of the body. The reduced section is internally and externally threaded. An inwardly tapered seat for an O-ring is formed in the shoulder. An O-ring positioned in the tapered seat is compressed and contained within the tapered seat to provide a water tight seal when the externally threaded end is threaded into a female fitting. The free end of the head is formed with an internally threaded socket. A washer seated at the bottom of the socket provides a water tight seal when the socket is screwed onto a male plumbing fitting.

Abstract: An electronic Storefront (website approach) provided through the Internet, where specific brands or advertisers are provided proprietary departments (Stores) to promote any variety of product incentives, i.e. coupons, rebates, discounts etc . . . to specific regions. These all-electronic transactions and communication are maintained in the Storefront's proprietary database provide tracking and identification of selected incentives, printed out and redeemed, as well as any rebates automatically provided through the proprietary software program utilizing indigenous tracking numbers or household identification number to every transaction. All of this is accomplished in a redemption-based remuneration approach.