Patents by Inventor Mark Alan Richardson

Mark Alan Richardson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Effect of compounds that suppress induction of plasminogen activator inhibitor 1 (PAI-1)
    Patent number: 5980938
    Abstract: The present invention provides methods of inhibiting PAI-1 using benzopyrans.
    Type: Grant
    Filed: June 25, 1997
    Date of Patent: November 9, 1999
    Assignee: Eli Lilly and Company
    Inventors: David Thompson Berg, George Joseph Cullinan, Brian William Grinnell, Mark Alan Richardson
  • Benzothiophene compounds, and uses and formulations thereof
    Patent number: 5962698
    Abstract: Novel benzothiophenes, and intermediates thereof, and the uses and formulations thereof, are provided by the present invention.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: October 5, 1999
    Assignee: Eli Lilly and Company
    Inventors: David Thompson Berg, George Joseph Cullinan, Brian William Grinnell, Mark Alan Richardson
  • Benzothiopene compounds, and uses and formulations thereof
    Patent number: 5948795
    Abstract: Novel benzothiophenes, ##STR1## wherein R.sub.1, R.sub.2, and R.sub.3 are independently --OH, --OCO(C.sub.1 -C.sub.6 alkyl), --O(CO)O(C.sub.1 -C.sub.6 alkyl), --OCO--Ar, where Ar is phenyl or substituted phenyl, or --O(CO)O--phenyl; and R.sub.4 is N-pyrrolidinyl, N-piperidinyl, or N-hexamethyleneimino, and intermediates thereof, and the uses and formulations thereof, are provided by the present invention.
    Type: Grant
    Filed: June 25, 1997
    Date of Patent: September 7, 1999
    Assignee: Eli Lilly and Company
    Inventors: David Thompson Berg, George Joseph Cullinan, Brian William Grinnell, Mark Alan Richardson
  • Method for inhibiting plasminogen activator inhibitor 1
    Patent number: 5792798
    Abstract: Methods of inhibiting plasminogen activator inhibitor 1 comprising administering to a human in need thereof an effective amount of a compound having the formula I: ##STR1## wherein R.sup.1 and R.sup.2 are, independently, --H, --C.sub.1 -C.sub.4 alkyl, or taken together with the nitrogen to which they are attached form a pyrrolidine, piperidine, or hexamethyleneimino ring;or a pharmaceutically acceptable salt or solvate thereof.
    Type: Grant
    Filed: July 15, 1997
    Date of Patent: August 11, 1998
    Assignee: Eli Lilly and Company
    Inventors: David Thompson Berg, George Joseph Cullinan, Brian William Grinnell, Mark Alan Richardson
  • Benzothiophene compounds, and uses formulations thereof
    Patent number: 5780648
    Abstract: Benzothiophenes, and uses and formulations thereof, are provided by the present invention.
    Type: Grant
    Filed: June 25, 1997
    Date of Patent: July 14, 1998
    Assignee: Eli Lilly and Company
    Inventors: David Thompson Berg, George Joseph Cullinan, Brian William Grinnell, Mark Alan Richardson
  • Methods of inhibiting plasminogen activator inhibitor 1
    Patent number: 5731328
    Abstract: A method of inhibiting plasminogen activator inhibitor 1 comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
    Type: Grant
    Filed: September 4, 1996
    Date of Patent: March 24, 1998
    Assignee: Eli Lilly and Company
    Inventors: David Thompson Berg, Brian William Grinnell, Mark Alan Richardson