Abstract: A guide device for assisting the application of a liquid from a dispenser to the eye of a subject has a mount to hold the liquid dispenser in the guide device, a rest to align the guide device with the subject head, and an indicator, selectively visible to indicate when the guide device is tilted at or beyond a minimum guide angle. Preferably, the indicator is selectively visible to indicate when the guide device is tilted at, or between, the minimum guide angle and a maximum guide angle. Said minimum guide angle corresponds with a minimum predetermined tilt of the subject head suitable for delivery of the liquid from the dispenser. The maximum guide angle corresponds with a maximum predetermined tilt of the subject head suitable for delivery of the liquid.

Abstract: A manifold for use in a medicament dispenser device for the delivery of medicament powder from an open blister pocket of a blister pack comprises a body defining a chimney having a chimney inlet and a chimney exit, and defining a chamber having a chamber inlet and a chamber exit, wherein the chimney exit and said chamber inlet lie side-by-side such that when the open blister pocket is positioned adjacent thereto airflow is directed from the chimney exit to the chamber inlet via the open blister pocket, and wherein one or more bleed holes are provided between the chimney and the chamber such that bleed airflow is able to be directed into the chamber to disruptively impact the airflow that transports the entrained medicament powder.

Abstract: A manifold for use in a medicament dispenser device for the delivery of medicament powder from an open blister pocket of a blister pack comprises a body defining a chimney having a chimney inlet and a chimney exit, and defining a chamber having a chamber inlet and a chamber exit, wherein the chimney exit and said chamber inlet lie side-by-side such that when the open blister pocket is positioned adjacent thereto airflow is directed from the chimney exit to the chamber inlet via the open blister pocket, and wherein one or more bleed holes are provided between the chimney and the chamber such that bleed airflow is able to be directed into the chamber to disruptively impact the airflow that transports the entrained medicament powder.

Abstract: A manifold for use in a medicament dispenser device for the delivery of medicament powder from an open blister pocket of a blister pack comprises a body, the body defining a chimney having a chimney inlet and a chimney exit for directing airflow from said chimney inlet to the chimney exit; the body further defining a chamber having a chamber inlet and a chamber exit, wherein the chimney exit and the chamber inlet lie side-by-side each other such that when the open blister pocket of the blister pack is positioned adjacent thereto the airflow is directed from the chimney exit to the chamber inlet via the open blister pocket to entrain the medicament powder and enable transport thereof in the airflow from the chamber inlet to the chamber exit, and wherein one or more bleed holes are provided between the chimney and the chamber such that bleed airflow is able to be directed into the chamber to disruptively impact the airflow that transports the entrained medicament powder.

Abstract: A medicament dispenser device suitable for the delivery of medicament powder from an open blister pocket of at least one blister pack, the dispenser device comprises (a) a housing; (b) provided to the housing, an air inlet; (c) enclosed by the housing, a dispensing mechanism for the dispensing of medicament powder from an open blister pocket of at least one blister pack receivable thereby; and (d) associated with the dispensing mechanism and in communication with said air inlet, a manifold comprising (i) a body, (ii) the body defining a chimney having a chimney inlet and a chimney exit for directing airflow from the chimney inlet to the chimney exit; (iii) the body further defining a chamber having a chamber inlet and a chamber exit, (iv) wherein the chimney exit and the chamber inlet lie side-by-side each other such that when the open blister pocket of the blister pack is positioned adjacent thereto the airflow will be directed from the chimney exit to the chamber inlet via the open blister pocket to entra

Abstract: A manifold for use in a medicament dispenser device for the delivery of medicament powder from an open blister pocket of a blister pack comprises a body, the body defining a chimney having a chimney inlet and a chimney exit for directing airflow from said chimney inlet to the chimney exit; the body further defining a chamber having a chamber inlet and a chamber exit, wherein the chimney exit and the chamber inlet lie side-by-side each other such that when the open blister pocket of the blister pack is positioned adjacent thereto the airflow is directed from the chimney exit to the chamber inlet via the open blister pocket to entrain the medicament powder and enable transport thereof in the airflow from the chamber inlet to the chamber exit, and wherein one or more bleed holes are provided between the chimney and the chamber such that bleed airflow is able to be directed into the chamber to disruptively impact the airflow that transports the entrained medicament powder.

Abstract: There is provided a valve for an aerosol container. The valve comprises a valve body; within the valve body, a sealing ring and receivable by the sealing ring, a valve stem having a dispensing passage. The valve stem is slidably movable within the sealing ring from a valve-closed position to a valve-open position in which the interior of the valve body is in communication with the dispensing passage. The sealing ring is shaped such as to reduce the contact area between the sealing ring and the valve stem. Preferably, the valve is a metering valve.

Abstract: There is provided according to the invention a metered dose inhaler for dispensing a medicament, comprising an interfacial surface having a fluorocarbon polymeric compound dispensed thereon, such that deposition of the medicament on the metered dose inhaler is reduced by between 30% and 80%. There are also provided for its preparation and its use in therapy.

Abstract: There is provided according to the invention a metered dose inhaler comprising an interfacial surface having the following properties: i) a contact angle of greater than 70 degrees; and ii) a conductivity of greater than 2.4 mS. There are also provided processes for its preparation and its use in therapy.

Abstract: There is provided according to the invention a metered dose inhaler comprising an interfacial surface having a linear non-cross-linked polymeric compound disposed thereon. There are also provided processes for its preparation and its use in therapy.