Patents by Inventor Mark Andrew Yondola

Mark Andrew Yondola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INFLUENZA HEMAGGLUTININ PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20220288189
    Abstract: In some embodiments the present invention provides influenza hemagglutinin (“HA”) polypeptides, proteins, and protein complexes that comprise a stalk domain that is engineered to facilitate maintenance of its native trimeric conformation, even if the head domain of the HA protein is removed or disrupted. In some embodiments, the present invention provides compositions comprising such polypeptides, proteins, and protein complexes, and methods of use of such proteins and compositions, for example as vaccine immunogens.
    Type: Application
    Filed: September 27, 2021
    Publication date: September 15, 2022
    Inventors: Christopher Patrick Marshall, Peter Joseph Alff, Claudio Bertuccioli, Mark Andrew Yondola
  • Influenza hemagglutinin proteins and methods of use thereof
    Patent number: 11129887
    Abstract: In some embodiments the present invention provides influenza hemagglutinin (“HA”) polypeptides, proteins, and protein complexes that comprise a stalk domain that is engineered to facilitate maintenance of its native trimeric conformation, even if the head domain of the HA protein is removed or disrupted. In some embodiments, the present invention provides compositions comprising such polypeptides, proteins, and protein complexes, and methods of use of such proteins and compositions, for example as vaccine immunogens.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: September 28, 2021
    Assignee: Calder Biosciences Inc.
    Inventors: Christopher Patrick Marshall, Peter Joseph Alff, Claudio Bertuccioli, Mark Andrew Yondola
  • INFLUENZA HEMAGGLUTININ PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20180243403
    Abstract: In some embodiments the present invention provides influenza hemagglutinin (“HA”) polypeptides, proteins, and protein complexes that comprise a stalk domain that is engineered to facilitate maintenance of its native trimeric conformation, even if the head domain of the HA protein is removed or disrupted. In some embodiments, the present invention provides compositions comprising such polypeptides, proteins, and protein complexes, and methods of use of such proteins and compositions, for example as vaccine immunogens.
    Type: Application
    Filed: December 22, 2017
    Publication date: August 30, 2018
    Inventors: Christopher Patrick Marshall, Peter Joseph Alff, Claudio Bertuccioli, Mark Andrew Yondola
  • INFLUENZA HEMAGGLUTININ PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20170072045
    Abstract: In some embodiments the present invention provides influenza hemagglutinin (“HA”) polypeptides, proteins, and protein complexes that comprise a stalk domain that is engineered to facilitate maintenance of its native trimeric conformation, even if the head domain of the HA protein is removed or disrupted. In some embodiments, the present invention provides compositions comprising such polypeptides, proteins, and protein complexes, and methods of use of such proteins and compositions, for example as vaccine immunogens.
    Type: Application
    Filed: June 15, 2016
    Publication date: March 16, 2017
    Inventors: Christopher Patrick Marshall, Peter Joseph Alff, Claudio Bertuccioli, Mark Andrew Yondola
  • Influenza hemagglutinin proteins and methods of use thereof
    Patent number: 9393297
    Abstract: In some embodiments the present invention provides influenza hemagglutinin (“HA”) polypeptides, proteins, and protein complexes that comprise a stalk domain that is engineered to facilitate maintenance of its native trimeric conformation, even if the head domain of the HA protein is removed or disrupted. In some embodiments, the present invention provides compositions comprising such polypeptides, proteins, and protein complexes, and methods of use of such proteins and compositions, for example as vaccine immunogens.
    Type: Grant
    Filed: August 2, 2014
    Date of Patent: July 19, 2016
    Assignee: AVATAR MEDICAL, LLC
    Inventors: Christopher Patrick Marshall, Peter Joseph Alff, Claudio Bertuccioli, Mark Andrew Yondola
  • INFLUENZA HEMAGGLUTININ PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20150056233
    Abstract: In some embodiments the present invention provides influenza hemagglutinin (“HA”) polypeptides, proteins, and protein complexes that comprise a stalk domain that is engineered to facilitate maintenance of its native trimeric conformation, even if the head domain of the HA protein is removed or disrupted. In some embodiments, the present invention provides compositions comprising such polypeptides, proteins, and protein complexes, and methods of use of such proteins and compositions, for example as vaccine immunogens.
    Type: Application
    Filed: August 2, 2014
    Publication date: February 26, 2015
    Inventors: Christopher Patrick Marshall, Peter Joseph Alff, Claudio Bertuccioli, Mark Andrew Yondola