Abstract: A multi-functional sensor assembly includes an electrically non-conductive substrate defining at least a distal region, intermediary region, and proximal region that are each covered with electrically conductive traces. The proximal region is configured to be exposed to a media to be sensed and the distal and intermediary regions are configured to be protected from the media. The electrically conductive traces comprise at least electrical circuits to sense temperature and flow of the media and one or more electrodes to sense one or more of conductivity, oxidation reduction potential (ORP), and acidity (pH) of the media.

Abstract: An interface for positive pressure respiratory therapy includes a mask assembly having a mask seal and a mask shell. The mask assembly is positioned lower than and exposes a bridge of the user's nose. The mask seal includes first and second portions on respective first and second sides of a nasal region that contact opposing sides of the user's nose. The first and second portions each include supports that help maintain a shape of the mask seal. A pair of covers can be supported relative to the mask assembly and adjacent a respective one of the first and second portions of the mask seal. The covers limit expansion of the first and second portions of the mask seal in response to pressurized air within the mask seal. The supports of the first and second portions can transfer load from the mask seal to the covers.

Abstract: Disclosed herein are systems, methods, and software for providing a platform for complex image data analysis using artificial intelligence and/or machine learning algorithms. One or more subsystems allow for the capturing of user input such as eye gaze and dictation for automated generation of findings. Additional features include quality metric tracking and feedback, and worklist management system and communications queueing.

Abstract: Skateboard trucks and skateboards using the improved trucks are disclosed. Truck according to the present invention can comprising a hanger with wheels. A base assembly is included having an at least partially hollow housing section. The hanger is rotationally mounted to the base assembly. The hanger also comprises a hanger portion that is within partially hollow housing section. Compressible spring elements are included within the partially hollow housing section, wherein the hanger portion operates on the compressible spring elements when the hanger rotates in relation to the base assembly. Skateboards are also disclosed that utilize the truck. One or more trucks are mounted to the skateboard deck with the truck having internal compressible spring elements that are compressed when turning the skateboard. The internal compressible spring elements also expand to return the truck to a neutral position when the skateboard is not turning.

Abstract: Provided are TCRs (e.g., TCRs that bind to NY-ESO-1), cells and pharmaceutical compositions comprising these TCRs, nucleic acids encoding these TCRs, expression vectors and host cells for making these TCRs, and methods of treating a subject using these TCRs.

Abstract: Independent component analysis may be performed on a plurality of detected electronic signals to separate signals within the detected electronic signals that are contributed by different sources. Each of the plurality of detected electronic signals may be received from a separate detector and may correspond to a detected optical signal emanating from a pregnant mammal's abdomen and a fetus contained therein. The detected optical signals may correspond to light that is projected into the pregnant mammal's abdomen from a light source. The separated signals may be analyzed to determine a separated signal that corresponds to light incident upon the fetus, which may be analyzed to determine a fetal hemoglobin oxygen saturation level of the fetus. An indication of the fetal hemoglobin oxygen saturation level may then be provided to the user.

Abstract: A device for creating a fistula between blood vessels operates in conjunction with a guidewire to locate and position itself so that it straddles both vessels and is able to draw them together. A fixing agent is released either from within the device or from an external needle, or both, into the procedural site. The fixing agent functions to hold the relative position of the two vessels, to seal the surrounding tissue so that any leaks that do occur don't spread into the tissue to create a hematoma, and to limit expansion of the fistula. After the vessels are in close proximity to each other and the fixing agent is applied, the device of the invention employs a cutting mechanism which opens a portal between the two vessels.

Abstract: Various embodiments include apparatus and methods implemented to take into consideration gauge length in optical measurements. In an embodiment, systems and methods are implemented to interrogate an optical fiber disposed in a wellbore, where the optical fiber is subjected to seismic waves, and to generate a seismic wavefield free of gauge length effect and/or to generate a prediction of a seismic wavefield of arbitrary gauge length, based on attenuation factors of a plurality of wavefields acquired from interrogating the optical fiber. In an embodiment, systems and methods are implemented to interrogate an optical fiber disposed in a wellbore, where the optical fiber is subjected to seismic waves, and to convert a seismic wavefield associated with a first gauge length to a seismic wavefield associated with a different gauge length that is a multiple of the first gauge length. Additional apparatus, systems, and methods are disclosed.

Abstract: There is provided a new and improved synthetic route for the synthesis of the compound 1-{2-[(1R)-1-aminoethyl]-4-chlorobenzyl}-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-one (Formula (I)) that is readily scalable for commercial production. Also provided are important intermediate compounds that are formed in the new and improved synthetic route for the synthesis of the compound of formula (I).

Abstract: A shower/commode wheeled chair adapted to be locatable over a commode, the shower/commode wheeled chair comprising a frame, a seat support portion, a front portion extending downwardly from the seat support portion, a back support, a shower/commode seat, wheels and a footrest coupled to the front portion.

Abstract: A guide for cutting a dowel pin of a rotor assembly is provided. The guide includes a catch basin, including a first catch basin portion and a second catch basin portion, and a shim. The first catch basin portion and the second catch basin portion form a cutting tool receiver. The shim extends from a first edge having a cross-section that is complementary to a surface of the rotor assembly. The first catch basin portion and the second catch basin portion form a receptacle that accommodates and retains portions of a dowel pin during and after removal of the dowel pin from the rotor assembly. The cutting tool receiver is defined by a receiver edge configured to guide a cutting surface of a cutting tool through a cross-section of a dowel pin.

Abstract: A recycling kiosk for recycling and financial remuneration for submission of an electronic device such as a mobile phone is disclosed herein. The recycling kiosk includes electrical connectors and an inspection area with an upper chamber, a lower chamber, a transparent plate and at least one camera in order to perform a visual analysis and an electrical analysis of the electronic device for determination of a value of the electronic device. The recycling kiosk also includes a processor and a display for user interaction.

Abstract: A blow molded article, a method of making a blow molded article and a method of making a preform each having at least one layer comprising a thermoplastic resin and between 0.1% and 20% of an additive having a viscosity of greater than 1,000,000 cst. There is a refractive index difference of at least 0.04 between the additive and the thermoplastic resin. The high viscosity of the additive ensures even distribution of the additive within the thermoplastic resin in discrete domains, while additionally providing for a complex end look balancing opacity, gloss and depth.

Abstract: An upper of an article of footwear comprises a plurality of stretch zones each having a respective stretching capability. Suitable example stretch zones may include four-way stretch zones, two-way stretch zones, and/or lock-out zones. In some examples, an upper having a plurality of stretch zones comprises a single continuous piece of material configured to have regions of different stretching capability. The single piece of material may comprise a layered material having two stretchable outer layers, wherein a plurality of stretch zones of the piece of material are defined by corresponding intermediate layers disposed at selected locations between the outer layers. Examples of intermediate layers providing two-way stretch, four-way stretch, and little or no stretch are disclosed.

Abstract: A personal care product is provided including an applicator head with a flat treatment sheet. The personal care product also includes a cover configured to surround the applicator head and to cover the treatment sheet. The cover includes a base with a planar outer surface. The cover also includes an outer rim around a perimeter of the planar outer surface and an inner rim configured to engage a portion of the applicator head. The planar outer surface of the base defines a plane. The personal care product includes a center of gravity with a projection in the plane, where the length of the one or more tabs along the plane exceeds a length between the projection and the inner rim along the plane.

Abstract: The disclosures herein relate to compounds of Formula (1?): or a salt thereof, wherein A, Q, X, Z, L, R2, R3 and R9 are defined herein, and their use in the treatment of SARS-CoV-2 and related viruses and disorders associated with SARS-CoV-2: Mpro.

Abstract: A personal care product is provided including an applicator head with a flat treatment sheet. The personal care product also includes a cover configured to surround the applicator head and to cover the treatment sheet. The cover includes a base with a planar outer surface. The cover also includes an outer rim around a perimeter of the planar outer surface and an inner rim configured to engage a portion of the applicator head. The planar outer surface of the base defines a plane. The personal care product includes a center of gravity with a projection in the plane, where the length of the one or more tabs along the plane exceeds a length between the projection and the inner rim along the plane.

Abstract: A personal care product is provided including an applicator head with a flat treatment sheet. The personal care product also includes a cover configured to surround the applicator head and to cover the treatment sheet. The cover includes a base with a planar outer surface. The cover also includes an outer rim around a perimeter of the planar outer surface and an inner rim configured to engage a portion of the applicator head. The planar outer surface of the base defines a plane. The personal care product includes a center of gravity with a projection in the plane, where the length of the one or more tabs along the plane exceeds a length between the projection and the inner rim along the plane.

Abstract: Methods, systems, computer-readable media, devices, and apparatuses for synchronized mode transitions are presented. A first device configured to be worn at an ear includes a processor configured to, in a first contextual mode, receive a first mode change request from a second device to transition at a first time to a second contextual mode. The first mode change request is based on detection of a trigger condition. The processor is further configured to, at the first time, transition from the first contextual mode to the second contextual mode based on the first mode change request.

Abstract: Compounds of formula (I) are described, wherein each of the variable groups is as defined in the specification. Also described are pharmaceutical compositions containing a compound of formula (I), and uses of the compounds and pharmaceutical compositions for inhibiting Nav1.8 voltage-gated sodium channels and treating Nav1.8 mediated diseases, disorders, and conditions, such as pain and pain-associated diseases, disorders, and conditions and cardiovascular diseases, disorders, and conditions, such as atrial fibrillation.