Abstract: The disclosure provides methods and systems for determining tissue oxygenation. An electronic device obtains a data set including a plurality of images of a tissue of interest, each resolved at a different spectral band. Spectral analysis is performed, upon image registration, at a plurality of points in a two-dimensional area of the images of the tissue. The spectral analysis including determining approximate values of oxyhemoglobin levels and deoxyhemoglobin levels at each respective point in the plurality of points. The predetermined set of eight to twelve spectral bands includes spectral bands that provide improved methods for measuring tissue oxygenation.

Abstract: Provided are methods and systems for concurrent imaging at multiple wavelengths. In one aspect, an imaging device includes at least one objective lens configured to receive light backscattered by an object, a plurality of pixel array photo-sensors, a plurality of bandpass filters covering respective photo-sensors, where each bandpass filter is configured to allow a different respective spectral band to pass through the filter, and a beam steering assembly in optical communication with the at least one objective lens and the photo-sensors. The beam steering assembly directs light received by at least one objective lens from the tissue of a subject to at least one pixel array photo-sensor in the plurality of pixel array photo-sensors.

Abstract: A hyperspectral/multispectral imager comprising a housing is provided. At least one light source is attached to the housing. An objective lens, in an optical communication path comprising originating and terminating ends, is further attached to the housing and causes light to (i) be backscattered by the tissue of a subject at the originating end and then (ii) pass through the objective lens to a beam steering element at the terminating end of the communication path inside the housing. The beam steering element has a plurality of operating modes each of which causes the element to be in optical communication with a different optical detector in a plurality of optical detectors offset from the optical communication path. Each respective detector filter in a plurality of detector filters covers a corresponding optical detector in the plurality of optical detectors thereby filtering light received by the corresponding detector from the beam steering element.

Abstract: A hyperspectral/multispectral imager comprising a housing is provided. At least one light source is attached to the housing. An objective lens, in an optical communication path comprising originating and terminating ends, is further attached to the housing and causes light to (i) be backscattered by the tissue of a subject at the originating end and then (ii) pass through the objective lens to a beam steering element at the terminating end of the communication path inside the housing. The beam steering element has a plurality of operating modes each of which causes the element to be in optical communication with a different optical detector in a plurality of optical detectors offset from the optical communication path. Each respective detector filter in a plurality of detector filters covers a corresponding optical detector in the plurality of optical detectors thereby filtering light received by the corresponding detector from the beam steering element.

Abstract: The disclosure provides methods and systems for determining tissue oxygenation. An electronic device obtains a data set including a plurality of images of a tissue of interest, each resolved at a different spectral band. Spectral analysis is performed, upon image registration, at a plurality of points in a two-dimensional area of the images of the tissue. The spectral analysis including determining approximate values of oxyhemoglobin levels and deoxyhemoglobin levels at each respective point in the plurality of points. The predetermined set of eight to twelve spectral bands includes spectral bands that provide improved methods for measuring tissue oxygenation.

Abstract: An imaging system collects a plurality of images of an extremity of a subject, each collected at a unique spectral band. A physiologic arterial parameter of the extremity is determined from the plurality of images upon image registration. A record of the physiological arterial parameter is recorded in an electronic data store and an indication of the parameter is outputted. The method is performed by a medical professional associated with a temporal clinical expenditure cost in an epoch, for an entity. The product of the (i) epoch and the (ii) temporal clinical expenditure cost is less than a difference between (a) an average or absolute reimbursement associated with the current procedural terminology code by the entity and (b) incidental expenditures associated with the performance of the method.

Abstract: Provided are methods and systems for concurrent imaging at multiple wavelengths. In one aspect, a hyperspectral/multispectral imaging device includes a lens configured to receive light backscattered by an object, a plurality of photo-sensors, a plurality of bandpass filters covering respective photo-sensors, where each bandpass filter is configured to allow a different respective spectral band to pass through the filter, and a plurality of beam splitters in optical communication with the lens and the photo-sensors, where each beam splitter splits the light received by the lens into a plurality of optical paths, each path configured to direct light to a corresponding photo-sensor through the bandpass filter corresponding to the respective photo-sensor.

Abstract: A hyperspectral/multispectral imager comprising a housing is provided. At least one light source is attached to the housing. An objective lens, in an optical communication path comprising originating and terminating ends, is further attached to the housing and causes light to (i) be backscattered by the tissue of a subject at the originating end and then (ii) pass through the objective lens to a beam steering element at the terminating end of the communication path inside the housing. The beam steering element has a plurality of operating modes each of which causes the element to be in optical communication with a different optical detector in a plurality of optical detectors offset from the optical communication path. Each respective detector filter in a plurality of detector filters covers a corresponding optical detector in the plurality of optical detectors thereby filtering light received by the corresponding detector from the beam steering element.

Abstract: The present disclosure generally relates to hyperspectral spectroscopy, and in particular, to systems, methods and devices enabling a single-sensor hyperspectral imaging device. Hyperspectral (also known as “multispectral”) spectroscopy is an imaging technique that integrates multiples images of an object resolved at different narrow spectral bands (i.e., narrow ranges of wavelengths) into a single data structure, referred to as a three-dimensional hyperspectral data cube. Data provided by hyperspectral spectroscopy allow for the identification of individual components of a complex composition through the recognition of spectral signatures of individual components within the three-dimensional hyperspectral data cube.

Abstract: Systems and methods for processing hyperspectral image via a computer network. At a server: obtaining, from a first client in a plurality of clients, a request for a unique patient identifier; in response to the request, generating the unique patient identifier independent of patient identity; storing the unique patient identifier and information identifying the first client in a server lookup table; and transmitting the unique patient identifier to the first client; receiving, from a hyperspectral imaging device, a hyperspectral image data set, which includes including a plurality of sub-images of an object and the unique patient identifier, and the unique patient identifier is associated with the plurality of sub-images; forming a hyperspectral image using the hyperspectral image data set; identifying the first client in the plurality of clients using the unique patient identifier and the server lookup table; and transmitting, to the first client, the hyperspectral image.

Abstract: A hyperspectral/multispectral imager comprising a housing is provided. At least one light source is attached to the housing. An objective lens, in an optical communication path comprising originating and terminating ends, is further attached to the housing and causes light to (i) be backscattered by the tissue of a subject at the originating end and then (ii) pass through the objective lens to a beam steering element at the terminating end of the communication path inside the housing. The beam steering element has a plurality of operating modes each of which causes the element to be in optical communication with a different optical detector in a plurality of optical detectors offset from the optical communication path. Each respective detector filter in a plurality of detector filters covers a corresponding optical detector in the plurality of optical detectors thereby filtering light received by the corresponding detector from the beam steering element.

Abstract: An apparatus for sensing a force. The apparatus includes a nanostructure being suitable for emitting electrons and a collector. The collector is proximately positioned with respect to the nanostructure so as to receive the emitted electrons and define a gap therebetween. The gap is partially dependent upon the applied force and the emission and reception of the electrons are indicative of the applied force.

Abstract: An apparatus for forming an image using an electrophoretic particle suspension containing media including: a transitioner for sufficiently lowering a viscosity of the suspension to facilitate mobility of at least some of the electrophoretic particles; and, imaging electrodes for selectively providing an imaging electric field associated with the image to be formed and positioned with respect to the transitioner such that the imaging electric field impinges upon the lowered viscosity suspension; wherein, the imaging electric field is sufficient to cause select ones of the electrophoretic particles in the lowered viscosity suspension to migrate depending upon the image to be formed.

Abstract: An apparatus for sensing a force. The apparatus includes a nanostructure being suitable for emitting electrons and a collector. The collector is proximately positioned with respect to the nanostructure so as to receive the emitted electrons and define a gap therebetween. The gap is partially dependent upon the applied force and the emission and reception of the electrons are indicative of the applied force.

Abstract: An apparatus for forming an image using an electrophoretic particle suspension containing media including: a transitioner for sufficiently lowering a viscosity of the suspension to facilitate mobility of at least some of the electrophoretic particles; and, imaging electrodes for selectively providing an imaging electric field associated with the image to be formed and positioned with respect to the transitioner such that the imaging electric field impinges upon the lowered viscosity suspension; wherein, the imaging electric field is sufficient to cause select ones of the electrophoretic particles in the lowered viscosity suspension to migrate depending upon the image to be formed.

Abstract: An apparatus for forming an image using an electrophoretic particle suspension containing media including: a transitioner for sufficiently lowering a viscosity of the suspension to facilitate mobility of at least some of the electrophoretic particles; and, imaging electrodes for selectively providing an imaging electric field associated with the image to be formed and positioned with respect to the transitioner such that the imaging electric field impinges upon the lowered viscosity suspension; wherein, the imaging electric field is sufficient to cause select ones of the electrophoretic particles in the lowered viscosity suspension to migrate depending upon the image to be formed.

Abstract: An improved modular solid power controller includes low cost low speed microcomputers embedded within the load cards to control a number of semiconductor power switches associated with corresponding electrical load circuits. A master controller microcomputer on the controller card communicates bilaterally with each of such slave microcomputers via a serial data path that extends along the backplane card and interconnects the former computer with each of the load cards, issuing commands in serial form and in high level language that is received by the addressed slave microprocessor, interpreted and acted upon by controlling the semiconductor power switches associated with the respective slave card.