Patents by Inventor Mark Arrington

Mark Arrington has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinoline and isoquinoline derivatives as phosphodiesterase 10 inhibitors
    Publication number: 20070299067
    Abstract: The present invention is directed to certain quinoline and isoquinoline compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds and processes for preparing such compounds. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
    Type: Application
    Filed: March 8, 2007
    Publication date: December 27, 2007
    Inventors: Ruiping Liu, Mark Arrington, Allen Hopper, Richard Conticello, Stephen Hitchcock
  • Phosphodiesterase 10 inhibitors
    Publication number: 20070287707
    Abstract: The present invention if directed to certain cinnoline compounds that are PDE10 inhibitors, pharmaceutical compounds containing the same and processes for preparing the same. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like.
    Type: Application
    Filed: February 27, 2007
    Publication date: December 13, 2007
    Inventors: Mark Arrington, Allen Hopper, Richard Conticello, Hans-Jurgen Hess, Stephen Hitchcock
  • Quinazoline derivatives as phosphodiesterase 10 inhibitors
    Publication number: 20070265258
    Abstract: The present invention if directed to certain quinazoline compounds that are PDE10 inhibitors, pharmaceutical compounds containing the same and processes for preparing the same. The invention is also directed to methods of treating diseases treatable by PDE10 enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like.
    Type: Application
    Filed: March 5, 2007
    Publication date: November 15, 2007
    Inventors: Ruiping Liu, Mark Arrington, Allen Hopper, Richard Conticello, Truc Nguyen, Carla Gauss, Stephen Hitchcock
  • Phosphodiesterase 10 inhibitors
    Publication number: 20070265256
    Abstract: The present invention is directed to certain cinnoline compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds and process for preparing such compounds. This invention is also directed to methods of treating diseases treatable by inhibition of PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
    Type: Application
    Filed: February 20, 2007
    Publication date: November 15, 2007
    Inventors: Mark Arrington, Ruiping Liu, Allen Hopper, Richard Conticello, Truc Nguyen, Carla Gauss, Roland Burli, Stephen Hitchcock, Essa Hu, Roxanne Kunz, Thomas Nixey, Shannon Rumfelt, Nign Chen
  • Cinnoline derivatives as phosphodiesterase 10 inhibitors
    Publication number: 20070265270
    Abstract: The present invention is directed to certain cinnoline compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds and process for preparing such compounds. The invention is also directed to methods of treating diseases treatable by modulation of PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
    Type: Application
    Filed: February 20, 2007
    Publication date: November 15, 2007
    Inventors: Stephen Hitchcock, Ruiping Liu, Mark Arrington, Allen Hopper, Richard Conticello, Truc Nguyen, M. Danca, Carla Gauss
  • Certain thienopyrimidine derivatives as phosphodiesterase 10 inhibitors
    Publication number: 20070259896
    Abstract: Certain thienopyrimidine derivatives are useful for the inhibition of PDE10 enzymes, and thus are useful for treating psychiatric or neurological syndromes, e.g., pyschoses, obsessive-compulsive disorder and/or Parkinson's disease, as well as, for example, treating a disease state modulated by PDE10 activity.
    Type: Application
    Filed: December 22, 2005
    Publication date: November 8, 2007
    Inventors: Ruiping Liu, Mark Arrington, Allen Hopper, Ashok Tehim
  • Phosphodiesterase 10 inhibitors
    Publication number: 20070093515
    Abstract: Provided are certain quinazolines that are PDE10 inhibitors, pharmaceutical compositions, containing the same and processes for preparing the same. Also provided are methods of treating diseases treatable by PDE10 enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like, by administering those certain quinazolines.
    Type: Application
    Filed: August 16, 2006
    Publication date: April 26, 2007
    Inventors: Mark Arrington, Richard Conticello, Carla Gauss, Stephen Hitchcock, Allen Hopper, Ruiping Liu, Truc Nguyen, Ashok Tehim
  • Phosphodiesterase 10 inhibitors
    Publication number: 20060160814
    Abstract: The present disclosure relates generally to the field of phosphodiesterase 10 (PDE10) enzyme inhibition by cinnoline compounds of Formulas I and II: wherein R1—R3 and R15—R18 are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
    Type: Application
    Filed: September 2, 2005
    Publication date: July 20, 2006
    Inventors: Mark Arrington, Ruiping Liu, Richard Conticello, Carla Gauss, Allen Hopper, Truc Nguyen, Ashok Tehim