Abstract: A tunneling device is provided for implanting a natural tissue vascular graft in a body. The tunneling device may include a flexible sheath to assist in locating the vascular graft in the body. According to one example, a connector having a longitudinal coupler, such as a surgical tie, may be used to locate the natural tissue graft within the sheath. The natural tissue graft can be secured to the surgical tie when the sheath is retracted. Before tunneling, the sheath can be extended to cover the natural tissue graft to protect the natural tissue graft from damage and aid in locating the natural tissue graft in the body. When the natural tissue graft is positioned as desired in the body, the sheath is removed.

Abstract: A barrier layer and corresponding method of making provide anti-inflammatory and anti-adhesion functionality for a medical device implantable in a patient. The barrier layer can be combined with a medical device structure to provide anti-adhesion characteristics, in addition to improved healing and anti-inflammatory response. The barrier layer is generally formed of a naturally occurring oil, or an oil composition formed in part of a naturally occurring oil, that is at least partially cured forming a cross-linked gel derived from at least one fatty acid compound. In addition, the oil composition can include a therapeutic agent component, such as a drug or other bioactive agent.