Patents by Inventor Mark B. Benjamin

Mark B. Benjamin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell lines and methods for assaying human interchromosomal recombination
    Patent number: 5554529
    Abstract: Cell lines useful for analysis of human homologous interchromosomal recombination are described. The cell lines carry endogenous mutant alleles of a selectable gene and can regenerate a selectable phenotype through homologous genetic recombination but not by large deletion of nucleotides or by chromosome loss. Assays using the cell lines permit quantitative and qualitative analysis of recombination events which occur between human chromosomes in somatic cells in culture. The assay relies on normal genes in their normal chromosomal site. The assays can be used to test for environmental agents which induce homologous recombination in human cells.
    Type: Grant
    Filed: May 9, 1994
    Date of Patent: September 10, 1996
    Assignee: President and Fellows of Harvard College
    Inventors: Mark B. Benjamin, John B. Little