Patents by Inventor Mark B. Chidlaw

Mark B. Chidlaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrogel-driven drug dosage form
    Patent number: 9028870
    Abstract: A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The drug-containing composition comprises a low-solubility drug and a drug-entraining agent. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of formulations having specific drug release profiles are disclosed.
    Type: Grant
    Filed: December 27, 2010
    Date of Patent: May 12, 2015
    Assignee: Bend Research, Inc.
    Inventors: Leah E. Appel, Ronald A. Beyerinck, Mark B. Chidlaw, William J. Curatolo, Dwayne T. Friesen, Kelly L. Smith, Avinash G. Thombre
  • HYDROGEL-DRIVEN DRUG DOSAGE FORM
    Publication number: 20110182947
    Abstract: A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The drug-containing composition comprises a low-solubility drug and a drug-entraining agent. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of formulations having specific drug release profiles are disclosed.
    Type: Application
    Filed: December 27, 2010
    Publication date: July 28, 2011
    Inventors: Leah E. Appel, Ronald A. Beyerinck, Mark B. Chidlaw, William J. Curatolo, Dwayne T. Friesen, Kelly L. Smith, Avinash G. Thombre
  • Hydrogel-driven layered drug dosage form
    Patent number: 6899896
    Abstract: A controlled release dosage form for sertraline has a core comprising a sertraline-containing composition and a water-swellable composition wherein the water-swellable composition is in a separate region within the core. A coating around the core is water-permeable, water-insoluble, and has at least one delivery port therethrough. In one embodiment, the dosage form releases sertraline to the use environment at an average rate of 6 to 10 wt % per hour from the second to the twenth hour after introduction to a use environment and less than about 25 wt % for the first two hours and at least 70 wt % by the twelfth hour, where the percentages correspond to the mass of drug released from the tablet divided by the total mass of drug originally present in the tablet.
    Type: Grant
    Filed: December 20, 2000
    Date of Patent: May 31, 2005
    Assignee: Pfizer Inc
    Inventors: William J. Curatolo, Kenneth C. Waterman, Avinash G. Thombre, Michael B. Fergione, Michael C. Roy, Leah A. Appel, Danni Supplee, Dwayne T. Friesen, Mark B. Chidlaw, Ronald A. Beyerinck
  • Controlled-Release of an active substance into a high fat environment
    Publication number: 20040121015
    Abstract: A controlled release delivery composition which can be administered to a high fat use environment such as the human gastrointestinal tract following a high fat meal. The delivery composition is embodied as a core surrounded by an asymmetric polymeric membrane. In a preferred embodiment, the asymmetric polymeric membrane is cellulose acetate.
    Type: Application
    Filed: December 3, 2003
    Publication date: June 24, 2004
    Applicant: Pfizer Inc
    Inventors: Mark B. Chidlaw, Dwayne T. Friesen, Scott M. Herbig, James A.S. Nightingale, Cynthia A. Oksanen, James B. West
  • Hydrogel-driven drug dosage form
    Publication number: 20040052845
    Abstract: A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of geometric arrangements are disclosed.
    Type: Application
    Filed: August 7, 2003
    Publication date: March 18, 2004
    Inventors: Leah E Appel, Walter C Babcock, Ronald A Beyerinck, Mark B Chidlaw, William J Curatolo, Dwayne T Friesen, Scott M Herbig, Avinash G Thombre
  • Hydrogel-driven drug dosage form
    Publication number: 20030086972
    Abstract: A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of geometric arrangements are disclosed.
    Type: Application
    Filed: August 1, 2001
    Publication date: May 8, 2003
    Inventors: Leah E. Appel, Walter C. Babcock, Ronald A. Beyerinck, Mark B. Chidlaw, William J. Curatolo, Dwayne T. Friesen, Scott M. Herbig, Avinash G. Thombre
  • Hydrogel-Driven Drug Dosage Form
    Publication number: 20020015731
    Abstract: A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The drug-containing composition comprises a low-solubility drug and a drug-entraining agent. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of formulations having specific drug release profiles are disclosed.
    Type: Application
    Filed: December 20, 2000
    Publication date: February 7, 2002
    Inventors: Leah E. Appel, Ronald A. Beyerinck, Mark B. Chidlaw, William J. Curatolo, Dwayne T. Friesen, Kelly L. Smith, Avinash G. Thombre
  • Hydrogel-driven layered drug dosage form
    Publication number: 20010044474
    Abstract: A controlled release dosage form for sertraline has a core comprising a sertraline-containing composition and a water-swellable composition wherein the water-swellable composition is in a separate region within the core. A coating around the core is water-permeable, water-insoluble, and has at least one delivery port therethrough. In one embodiment, the dosage form releases sertraline to the use environment at an average rate of 6 to 10 wt % per hour from the second to the twenth hour after introduction to a use environment and less than about 25 wt % for the first two hours and at least 70 wt % by the twelfth hour, where the percentages correspond to the mass of drug released from the tablet divided by the total mass of drug originally present in the tablet.
    Type: Application
    Filed: December 20, 2000
    Publication date: November 22, 2001
    Inventors: William J. Curatolo, Kenneth C. Waterman, Avinash G. Thombre, Michael B. Fergione, Michael C. Roy, Leah E. Appel, Danni Supplee, Dwayne T. Friesen, Mark B. Chidlaw, Ronald A. Beyerinck
  • Process of making polyvinylidene fluoride membranes
    Patent number: 5565153
    Abstract: Multi-step methods of making a non-skinned isotropic microfiltration membrane, the common steps of which include heating a PVDF-type casting dope above its cloudpoint, forming a film, and immersing the film in a gelation bath.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: October 15, 1996
    Assignee: Sartorius AG
    Inventors: Mark B. Chidlaw, Dwayne T. Friesen, Carol A. Thornton, Donald J. Kelly, Daniel J. Brose