Patents by Inventor Mark B. Frank

Mark B. Frank has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies for DNA-RNA hybrid complexes and their uses
    Patent number: 4865980
    Abstract: Monoclonal antibodies are provided capable of distinguishing DNA-RNA hybrid complexes from single stranded DNA and RNA and double stranded DNA and RNA. The antibodies find particular use in determining the presence of a specific nucleic acid sequence on a solid surface. Single stranded polynucleotide is fixed to a solid (gel) surface and then hybridized with the complementary probe. The hybrid complex specific monoclonal antibody is then added to bind to any hybrid complexes which have formed. By appropriate label, the hybrid complex may be visualized in a variety of ways.
    Type: Grant
    Filed: February 12, 1988
    Date of Patent: September 12, 1989
    Assignee: University of Hawaii
    Inventors: W. Dorsey Stuart, Mark B. Frank
  • Monoclonal antibodies for DNA-RNA hybrid complexes and their uses
    Patent number: 4732847
    Abstract: Monoclonal antibodies are provided capable of distinguishing DNA-RNA hybrid complexes from single stranded DNA and RNA and double stranded DNA and RNA. The antibodies find particular use in determining the presence of a specific nucleic acid sequence on a solid surface. Single stranded polynucleotide is fixed to a solid (gel) surface and then hybridized with the complementary probe. The hybrid complex specific monoclonal antibody is then added to bind to any hybrid complexes which have formed. By appropriate label, the hybrid complex may be visualized in a variety of ways.
    Type: Grant
    Filed: December 29, 1982
    Date of Patent: March 22, 1988
    Assignee: University of Hawaii
    Inventors: W. Dorsey Stuart, Mark B. Frank