Abstract: A computer-implemented system and method for controlling work flow management to improve the operational efficiency of a multi-room particle therapy medical center are disclosed. In one embodiment, the system includes a monitoring system configured through an active connection to receive real-time information about the current actions of the people, hardware and software at the center, an analysis system configured through an active connection to synthesize the information attained through the monitoring system, and a control system configured through an active connection that uses information acquired by the monitoring system to continuously update information made available through a set of user interfaces to an end user. Features also are provided to automatically synchronize, obtain, and update status information on the shared resources in the particle therapy medical center. Various ways of handling the data aggregation issues associated with compiling status data are also described.