Abstract: An optical sensor system comprising: (a) a light source for at least one optical sensor, the light source comprising at least, (i) an interposer having first and second opposing sides and defining at least one alignment aperture extending from the first opposing side to the second opposing side; (ii) at least one fiber disposed in the at least one alignment aperture, the at least one fiber having a first optical axis; (iii) at least one light emitting component mounted to the second opposing side and having a second optical axis coincident with the first optical axis, the light emitting component configured to emit light, at least a portion of which is coupled with the at least one fiber as coupled light; and (b) the at least one optical sensor optically coupled to the at least one fiber.

Abstract: An optical subassembly comprising: (a) an interposer having first and second opposing sides and defining at least one alignment aperture extending from said first opposing side to said second opposing side; (b) at least one fiber having a first optical axis disposed in said at least one alignment aperture; (c) at least one optical component mounted to said second opposing side having a second optical axis coincident with said first optical axis and defining an interface between said at least one optical component and said at least one optical component; and (d) a feedback component disposed on interposer within line-of-sight of said interface to receive at least a portion of uncoupled light emitted from said interface.

Abstract: A backplane connector for mating with a daughter-card connector assembly, said backplane connector having a front and rear orientation and comprising: (a) a retainer block configured for attachment to a backplane and defining a plurality of ferrule slots, each slot configured to receive a ferrule; (b) a plurality of ferrules disposed in said ferrule slots; (c) a plurality of ferrule springs to urge said plurality of ferrules forwardly; and (d) Fwafera plurality of ferrule spring retainers for retaining said ferrule springs and being mounted rearward on said retainer block, wherein each ferrule spring retainer retains springs for two or more ferrules.

Abstract: A daughter-card connector assembly comprising: (a) a housing defining a first plane configured for mounting parallel to a backplane, and a second plane for mounting parallel to a daughter card, and a plurality of parallel slots perpendicular to said first plane; and (b) one or more opto-electric cards, each of said one or more opto-electric cards disposed in one of said plurality of slots, and comprising at least, (i) a printed circuit board (PCB) defining at least a first edge and a second edge, wherein, when said opto-electric card is mounted in said slot, said first edge is parallel to said first plane and said second edge is parallel to said second plane; (ii) a blind-mate optical connector along said first edge; (iii) an electrical interface along said second edge; (iv) at least one optical component mounted on said PCB for converting between electrical and optical signals, said PCB being electrically connected to at least a portion of said electrical interface; and (v) one or more waveguides connecting

Abstract: A connector for attachment to a planar surface, said connector comprising a shell housing configured for attachment to said planar surface, an insert housing connected to said shell and defining two or more insert ferrule openings, at least one retainer attached to said insert housing and defining two or more retainer ferrule openings aligned with said insert ferrule openings, and two or more ferrule assemblies disposed within said two or more insert ferrule openings.

Abstract: A population of genetically engineered immune cells (e.g., T cells), which express a chimeric antigen receptor (CAR) specific to CD19 and contain a disrupted TRAC gene, a disrupted B2M gene, or both, for use in treating a B cell malignancy.

Abstract: A population of genetically engineered immune cells (e.g., T cells), which express a chimeric antigen receptor (CAR) specific to CD19 and contain a disrupted TRAC gene, a disrupted B2M gene, or both, for use in treating a B cell malignancy.

Abstract: An optical sensor system comprising: (a) a light source for at least one optical sensor, the light source comprising at least, (i) an interposer having first and second opposing sides and defining at least one alignment aperture extending from the first opposing side to the second opposing side; (ii) at least one fiber disposed in the at least one alignment aperture, the at least one fiber having a first optical axis; (iii) at least one light emitting component mounted to the second opposing side and having a second optical axis coincident with the first optical axis, the light emitting component configured to emit light, at least a portion of which is coupled with the at least one fiber as coupled light; and (b) the at least one optical sensor optically coupled to the at least one fiber.

Abstract: A population of genetically engineered immune cells (e.g., T cells), which express a chimeric antigen receptor (CAR) specific to CD19 and contain a disrupted TRAC gene, a disrupted ?2M gene, or both, for use in treating a B cell malignancy.

Abstract: Methods for treating a B cell malignancy comprising a population of genetically engineered immune cells (e.g., T cells), which express a chimeric antigen receptor (CAR) specific to CD19 and optionally an NK cell inhibitor (e.g., daratumumab). The genetically engineered immune cells may comprise a disrupted TRAC gene, a disrupted ?2M gene, or both.

Abstract: A connector for attachment to a planar surface, said connector comprising a shell housing configured for attachment to said planar surface. an insert housing connected to said shell and defining two or more insert ferrule openings, at least one retainer attached to said insert housing and defining two or more retainer ferrule opening aligned with said insert ferrule openings, and two or more ferrule assemblies disposed within said two or more insert ferrule openings.

Abstract: A population of genetically engineered immune cells (e.g., T cells), which express a chimeric antigen receptor (CAR) specific to CD19 and contain a disrupted TRAC gene, a disrupted B2M gene, or both, for use in treating a B cell malignancy.

Abstract: An optical subassembly comprising: (a) an interposer having first and second opposing sides and defining at least one alignment aperture extending from said first opposing side to said second opposing side; (b) at least one fiber having a first optical axis disposed in said at least one alignment aperture; (c) at least one optical component mounted to said second opposing side having a second optical axis coincident with said first optical axis and defining an interface between said at least one optical component and said at least one optical component; and (d) a feedback component disposed on interposer within line-of-sight of said interface to receive at least a portion of uncoupled light emitted from said interface.

Abstract: A sensor for detecting the level of accumulation of a material along an axis in a fluid environment, the sensor comprising (a) an optically transparent body having a third refractive index and an exposed surface defining a length extending at least partially in the direction of the axis; (b) at least one light delivery source for delivering light to the body such that the light is distributed along the length of the exposed surface; and at least one light receiver for receiving reflected light from the length of the exposed surface, wherein the amount of the reflected light depends on the level of the material accumulated along the length of the exposed surface.

Abstract: A sensor for detecting the level of accumulation of a material along an axis in a fluid environment, the sensor comprising (a) an optically transparent body having a third refractive index and an exposed surface defining a length extending at least partially in the direction of the axis; (b) at least one light delivery source for delivering light to the body such that the light is distributed along the length of the exposed surface; and at least one light receiver for receiving reflected light from the length of the exposed surface, wherein the amount of the reflected light depends on the level of the material accumulated along the length of the exposed surface

Abstract: Apparatus comprising an optical fiber laser having at least two laser cores and means arranged to combine laser output from the at least two laser cores at a first end of the optical fiber laser to produce a combined laser output having one or more beat signals.

Abstract: Apparatus comprising an optical fibre laser having at least two laser cores and means arranged to combine laser output from the at least two laser cores at a first end of the optical fibre laser to produce a combined laser output having one or more beat signals.

Abstract: This invention relates to methods and apparatus for covert illumination. The method involves illuminating the scene with light which is tuned to an absorption resonances of atmospheric oxygen gas. Light tuned to have a wavelength corresponding to an oxygen absorption wavelength travelling through the atmosphere is therefore attenuated by absorption. The method therefore teaches that a low power illumination source can be used to illuminate nearby objects, thus allowing the detail thereof to be resolved, and the illuminating light reflected from the object, or even the light source itself, will be undetectable beyond a certain range due to atmospheric absorption. The illumination may be used in conjunction with the use of low light level imagers to image a scene. Alternatively the illumination could be used for short range optical communication which will be undetectable at much longer range.

Abstract: The device includes a housing, a locking and release mechanism, an electrical connector, an optical connector, and pathological circuitry. The housing has a top, a bottom, a front, and a back. The locking and release mechanism is attached to the housing. The electrical connector is attached to the back of the housing. The optical connector is attached to the front of the housing. The pathological circuitry handles pathological conditions associated with digital video signals.

Abstract: The device includes a first optical connector, a second optical connector, a flexible substrate, a first electrical connector, a second electrical connector, a memory chip, and a clip. The first electrical connector is attached to the flexible substrate. The second electrical connector is attached to the flexible substrate. The memory chip is attached to the flexible substrate. A clip retains the first optical connector and the second optical connector adjacent to the flexible substrate.