Patents by Inventor MARK BIRRELL

MARK BIRRELL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF IKK-B GENE
    Publication number: 20080108584
    Abstract: The invention relates to a doable-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the IKK-B gene, comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of the IKK-B gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases, caused by the expression or activation of the IKK-B gene using the pharmaceutical composition; and methods for inhibiting the expression of the IKK-B gene in a cell.
    Type: Application
    Filed: May 21, 2007
    Publication date: May 8, 2008
    Inventors: ANTONIN DE FOUGEROLLES, ANDREW SPRAGUE, JENS HARBORTH, MARIA BELVISI, MARK BIRRELL, ELIZABETH HARDAKER, MATTHEW CATLEY