Abstract: Provided herein are methods and pharmaceutical compositions related to the bacteria and microbial extracellular vesicles (mEVs) of Prevotella histicola Strain C that are useful as therapeutic agents, e.g., for treating inflammatory diseases (e.g., a neuroinflammatory disease).

Abstract: A method and system of training in conjunction with a computer animation executed by a computing environment is described. The method includes recognizing a task to be performed in the computer animation, recognizing a problem, displayed in the computer animation, to accomplish the task, and solving the problem by manipulation of a virtual apparatus having virtual components displayed in the computer animation. The virtual components are manipulated by a student or user desiring to learn. The student is taught to understand logically consistent goals by using the virtual apparatus and without language interaction. Rules and properties for a subject area are modeled to the student by the virtual apparatus without language interaction. The student is taught to operate the virtual apparatus without language interaction. The student is requested to operate the virtual apparatus to reach goals in a sequence of problems having progressive difficulty and without language interaction.

Abstract: Cortical entrainment device (CED) and associated methods are provided. The CED device includes an electroencephalographic (EEG) analysis module configured to receive and process an EEG waveform for analyzing brain activity of a patient with epilepsy or a seizure disorder; an interictal epileptiform discharge (IED) analysis module configured to receive and process an IED waveform for analyzing the brain activity of the patient; and a diagnostic module that is configured to interface with the EEG analysis module and the IED analysis module, to evaluate spectral and temporal waveform characteristics, and to provide instructions to a therapy module for providing a stimulus for the patient based on the analysis by the EEG analysis module and the IED analysis module.

Abstract: A method using a spatial-temporal software game for both teaching math concepts to a child and for scoring the child's proficiency in these math concepts. These scores are compared with the child's performance on a language-based test of the math concepts. If the child's score on the language-based test is lower than what is reflected by the child's game scores, instruction is given the child using stories and flashcards related to the spatial-temporal software games so that the child will relate vocabulary terms with the math concepts and characters in the temporal-spatial software game.

Abstract: Embodiments of systems and methods are disclosed that analyze student performance and provide feedback regarding the student performance, for example, to an instructor, other school official, parent or directly to the student. In certain embodiments, the methods and systems communicate in real time with the educational program, for example, math or science games, lessons, quizzes or tests, to provide contemporaneous feedback or recommendations to the instructor regarding student performance. In addition, embodiments of the systems and methods evaluate and provide feedback of the effectiveness of the educational program itself, and track progress at different levels, for example, a student, class, school or district level, over a multitude of different durations and time periods. Still further, embodiments of the systems and methods perform comprehensive data analysis and statistical computations.

Abstract: A method and system of training in conjunction with a computer animation executed by a computing environment is described. The method includes recognizing a task to be performed in the computer animation, recognizing a problem, displayed in the computer animation, to accomplish the task, and solving the problem by manipulation of a virtual apparatus having virtual components displayed in the computer animation. The virtual components are manipulated by a student or user desiring to learn. The student is taught to understand logically consistent goals by using the virtual apparatus and without language interaction. Rules and properties for a subject area are modeled to the student by the virtual apparatus without language interaction. The student is taught to operate the virtual apparatus without language interaction. The student is requested to operate the virtual apparatus to reach goals in a sequence of problems having progressive difficulty and without language interaction.

Abstract: A method using a spatial-temporal software game for both teaching math concepts to a child and for scoring the child's proficiency in these math concepts. These scores are compared with the child's performance on a language-based test of the math concepts. If the child's score on the language-based test is lower than what is reflected by the child's game scores, instruction is given the child using stories and flashcards related to the spatial-temporal software games so that the child will relate vocabulary terms with the math concepts and characters in the temporal-spatial software game.

Abstract: A method and system of training in conjunction with a computer animation executed by a computing environment is described. The method includes recognizing a task to be performed in the computer animation, recognizing a problem, displayed in the computer animation, to accomplish the task, and solving the problem by manipulation of a virtual apparatus having virtual components displayed in the computer animation. The virtual components are manipulated by a student or user desiring to learn. The student is taught to understand logically consistent goals by using the virtual apparatus and without language interaction. Rules and properties for a subject area are modeled to the student by the virtual apparatus without language interaction. The student is taught to operate the virtual apparatus without language interaction. The student is requested to operate the virtual apparatus to reach goals in a sequence of problems having progressive difficulty and without language interaction.

Abstract: A method using a spatial-temporal software game for both teaching math concepts to a child and for scoring the child's proficiency in these math concepts. These scores are compared with the child's performance on a language-based test of the math concepts. If the child's score on the language-based test is lower than what is reflected by the child's game scores, instruction is given the child using stories and flashcards related to the spatial-temporal software games so that the child will relate vocabulary terms with the math concepts and characters in the temporal-spatial software game.

Abstract: Embodiments of systems and methods are disclosed that analyze student performance and provide feedback regarding the student performance, for example, to an instructor, other school official, parent or directly to the student. In certain embodiments, the methods and systems communicate in real time with the educational program, for example, math or science games, lessons, quizzes or tests, to provide contemporaneous feedback or recommendations to the instructor regarding student performance. In addition, embodiments of the systems and methods evaluate and provide feedback of the effectiveness of the educational program itself, and track progress at different levels, for example, a student, class, school or district level, over a multitude of different durations and time periods. Still further, embodiments of the systems and methods perform comprehensive data analysis and statistical computations.

Abstract: A method using a spatial-temporal software game for both teaching math concepts to a child and for scoring the child's proficiency in these math concepts. These scores are compared with the child's performance on a language-based test of the math concepts. If the child's score on the language-based test is lower than what is reflected by the child's game scores, instruction is given the child using stories and flashcards related to the spatial-temporal software games so that the child will relate vocabulary terms with the math concepts and characters in the temporal-spatial software game.