Patents by Inventor Mark Bowe

Mark Bowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of muscular dystrophies and related disorders
    Patent number: 7759314
    Abstract: The invention provides, among other aspects, compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; diseases or conditions associated with an abnormal level or activity of collagen VI; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); and disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation.
    Type: Grant
    Filed: August 15, 2002
    Date of Patent: July 20, 2010
    Assignee: Brown University
    Inventors: Justin R. Fallon, Michael Rafii, Alison Amenta, Mark Bowe, Beth McKechnie, Mary Lynn Mercado, Hiroki Hagiwara
  • Biglycan and related therapeutics and methods of use
    Publication number: 20050059580
    Abstract: The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Examples of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders.
    Type: Application
    Filed: June 14, 2004
    Publication date: March 17, 2005
    Applicant: Brown University Research Foundation
    Inventors: Justin Fallon, Beth McKechnie, Michael Rafii, Hilliary Creely, Mark Bowe, Raymond Ferri