Abstract: A probe for non-intrusively detecting imperfections in a test object made from metallic, non-conductive, and/or composite materials. The probe may include a capacitive measuring apparatus that includes at least two coplanar electrodes, an adjustment device to adjust a spatial separation between the electrodes, and a separation device. The separation device may maintain a substantially constant distance between the at least two coplanar electrodes and the test object during test measurements.

Abstract: Methods and systems for managing aircraft modifications. A link to a customer information database is established in response to receiving a launch input for a modification marketplace entered by a user via a graphical user interface. The customer information database includes identification information and customer information associated with the user. A determination is made as to whether the user is authorized to access the modification marketplace using the identification information. A link to an engineering database containing aircraft product information is established in response to a determination that the user is authorized to access the modification marketplace. A selected level of access to the aircraft product information in the engineering database is provided, via the graphical user interface, based on the customer information associated with the user.

Abstract: A probe for non-intrusively detecting imperfections in a test object made from metallic, non-conductive, and/or composite materials. The probe may include a capacitive measuring apparatus that includes at least two coplanar electrodes, an adjustment device to adjust a spatial separation between the electrodes, and a separation device. The separation device may maintain a substantially constant distance between the at least two coplanar electrodes and the test object during test measurements.

Abstract: A probe for non-intrusively detecting imperfections in a test object made from metallic, non-conductive, and/or composite materials. The probe may include a capacitive measuring apparatus that includes at least two coplanar electrodes, an adjustment device to adjust a spatial separation between the electrodes, and a separation device. The separation device may maintain a substantially constant distance between the at least two coplanar electrodes and the test object during test measurements.

Abstract: A method for non-intrusively detecting imperfections in a test object made from metallic, non-conductive, and/or composite materials. The method uses a database with predetermined reference values and a probe that comprises a capacitive measuring apparatus with at least two coplanar electrodes. The method includes the operations of placing the at least two coplanar electrodes into a first position that is at a predetermined distance from the test object, performing a capacitive measurement to determine an effective dielectric constant, retrieving a reference value of the predetermined reference values from the database based on the test object and the predetermined distance, and detecting imperfections in the test object based on a comparison of the effective dielectric constant with the reference value.

Abstract: Methods and systems for managing modifications to aircraft using a graphical user interface. A navigation section is displayed in the graphical user interface and includes at least one of a models menu control or a scenarios menu control. The models menu control is selectable to present model options to a user, the model options being customized based on at least one of identification information associated or customer information. The scenarios menu control is selectable to present scenario options to a user, the scenario options being tailored for the customer based on the at least one of identification information associated with the user or customer information retrieved for the customer. An effectivity selector allows the user to select a set of aircraft for modification. Based on the set of aircraft selected, features displayed in the graphical user interface based on an option from the model or scenario options are customized automatically.

Abstract: Methods and systems for managing aircraft modifications. A link to a customer information database is established in response to receiving a launch input for a modification marketplace entered by a user via a graphical user interface. The customer information database includes identification information and customer information associated with the user. A determination is made as to whether the user is authorized to access the modification marketplace using the identification information. A link to an engineering database containing aircraft product information is established in response to a determination that the user is authorized to access the modification marketplace. A selected level of access to the aircraft product information in the engineering database is provided, via the graphical user interface, based on the customer information associated with the user.

Abstract: Methods and systems for building a configuration for a new aircraft. A link to a customer information database is established in response to receiving a launch input for a production marketplace entered by a user via a graphical user interface. The user is associated with a customer. The customer information database includes identification information associated with the user. A determination is made as to whether the user is authorized to access the production marketplace using the identification information user. Guidance information is generated for presentation via the graphical user interface to guide the user through a build process for building the configuration in response to the user being authorized to access the production marketplace, the guidance information being customized for the customer. Feature selections are received by the user via the graphical user interface. The configuration is built for the new aircraft based on the feature selections.

Abstract: A probe for non-intrusively detecting imperfections in a test object made from metallic, non-conductive, and/or composite materials. The probe may include a capacitive measuring apparatus that includes at least two coplanar electrodes, an adjustment device to adjust a spatial separation between the electrodes, and a separation device. The separation device may maintain a substantially constant distance between the at least two coplanar electrodes and the test object during test measurements.

Abstract: A method for non-intrusively detecting imperfections in a test object made from metallic, non-conductive, and/or composite materials. The method uses a database with predetermined reference values and a probe that comprises a capacitive measuring apparatus with at least two coplanar electrodes. The method includes the operations of placing the at least two coplanar electrodes into a first position that is at a predetermined distance from the test object, performing a capacitive measurement to determine an effective dielectric constant, retrieving a reference value of the predetermined reference values from the database based on the test object and the predetermined distance, and detecting imperfections in the test object based on a comparison of the effective dielectric constant with the reference value.

Abstract: The invention provides, among other aspects, compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; diseases or conditions associated with an abnormal level or activity of collagen VI; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); and disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation.

Abstract: A heart monitor for use as a non-invasive screening tool for identifying potential atrial fibrillation in patients comprises a sensor for producing an output waveform of the patient's actual sinus rhythm, a processing unit arranged to store the normalized waveform of an ideal sinus rhythm and to compare the actual and ideal sinus rhythm waveforms and to produce an output dependant on the difference on a display. The value of the output is indicative of whether the patient is atrial fibrillation or other cardiac arrhythmia.

Abstract: The invention provides, among other aspects, compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; diseases or conditions associated with an abnormal level or activity of collagen VI; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); and disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation.

Abstract: The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Example of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders.

Abstract: The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Examples of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders.

Abstract: The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Example of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders.

Abstract: The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Example of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders.

Abstract: The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Examples of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders.

Abstract: The invention provides, among other aspects, compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; diseases or conditions associated with an abnormal level or activity of collagen VI; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); and disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation.

Abstract: The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Examples of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders.