Abstract: A computer-implemented process and apparatus for storing, accessing, and comparing genetic profiles in a form suitable for amateur human analysis is provided. The process includes imputing and storing data that represent individual genetic profiles which have been created using conventional genetic analysis processes. The process and apparatus allow remote consumer access via the internet to genetic profiles owned by consumer which can then be compared against other genetic profiles according to a genetic profile comparison process selected from several available processes. The resulting output of the process is a summary of the genetic profile comparison which answers the question posed by the consumer.

Abstract: A computer-implemented process and apparatus for storing, accessing, and comparing genetic profiles in a form suitable for amateur human analysis is provided. The process includes imputing and storing data that represent individual genetic profiles which have been created using conventional genetic analysis processes. The process and apparatus allow remote consumer access via the Internet to genetic profiles owned by consumer which can then be compared against other genetic profiles according to a genetic profile comparison process selected from several available processes. The resulting output of the process is a summary of the genetic profile comparison which answers the question posed by the consumer.

Abstract: The present invention relates to the inhibitors of MDM2 Binding Protein (MTBP) activity that may be used as medicaments. Such medicaments may be used to prevent or treat cancers. A preferred inhibitor is an siRNA molecule that is specific for silencing MTBP expression. The invention further relates to screening methods (e.g. for identifying MTBP inhibitors that may be used to treat cancers).

Abstract: A method and system to verify a transaction are described. The system may include a token generator to issue a client set of tokens to a client, a token verification list generator to issue a verification set of tokens to a provider, a communication module to receive a request from the provider to redeem a provider set of tokens, and a redemption module. The redemption module may be configured to compare the provider set of tokens with the client set of tokens and to selectively redeem the provider set of tokens based on the results of the comparison.

Abstract: A borehole entry apparatus is disclosed. The apparatus includes a dual entry apparatus for use in borehole entry applications, such as slick line and/or wireline (electric wireline) applications. Exemplary embodiments of this invention enable first and second borehole entry apparatuses, such as slick line and wireline tool assemblies, to be simultaneously coupled to a well head. Use of the invention tends to advantageously save rig time and thus reduce the cost of slick line and wireline operations, in particular on a deep-water offshore drilling rig.

Abstract: Isolated nucleic acid sequences encoding mammalian MDM2 binding protein and polypeptide sequences for the mammalian MDM2 binding protein are provided. Also provided are vectors containing these nucleic acid sequences, host cells which express these proteins and antibodies targeted to these proteins. In addition, methods and compositions for modulating the G1 phase of the cell cycle via altering expression and/or activity of a mammalian MDM2 binding protein are provided.

Abstract: A method and system for aiding rescue workers in properly identifying dwellings that may be in the need of search and rescue occupants of dwellings during natural disasters and other emergency events. The system and method also help rescue workers prioritize the search and rescue efforts to target those dwellings where the occupants have decided to remain, say during a hurricane. Typically, the system includes three decals, two for the resident and one used by rescue workers. The resident typically places either an occupied or vacant decal on the dwelling. The rescue worker can place a search complete decal after appropriate searching has been complete.

Abstract: Isolated nucleic acid sequences encoding mammalian MDM2 binding protein and polypeptide sequences for the mammalian MDM2 binding protein are provided. Also provided are vectors containing these nucleic acid sequences, host cells which express these proteins and antibodies targeted to these proteins. In addition, methods and compositions for modulating the G1 phase of the cell cycle via altering expression and/or activity of a mammalian MDM2 binding protein are provided.

Abstract: A vapor trap for detecting VOCs includes a housing, having a first end portion, a second end portion and at least one opening for receiving gas vapor. The housing is at least partially buried in ground with a vapor containment mechanism detachably connected to the first end portion of the housing. The vapor containment mechanism can be removed and replaced with a vapor sampling mechanism. An organic vapor analyzer can be connected in fluid relationship to the vapor sampling mechanism to measure VOCs. Optionally, a vacuum pump can be utilized to draw vapor into the vapor trap and then subsequently into the organic vapor analyzer. There can be a first selector valve located between the vapor sampling mechanism and the vacuum pump and a second selector valve located between the vapor sampling mechanism and the organic vapor analyzer. A preferred organic vapor analyzer is a photo-ionization detector.

Abstract: A washout arrangement for a well where a washout process is to take place to wash cement out of an annulus between two concentric casings 10, 16. Washports 36 are provided in a casing hanger 18, and an axially movable, telescopically extending lower body 40 is provided in a running tool 26 which is to engage with the casing hanger. When the running tool and casing hanger are engaged with each other, the lower body 40 can be moved axially (for example by mounting the lower body on a thread within the running tool and then rotating the lower body) between a position where it closes the washports and a position where the ports are open.

Abstract: A tool for incorporation in a drill string has an outer body (11, 12, 13) and a spool (17, 18, 19) rotationally and slidably mounted within the body. A cam groove (20) is formed on camming component (17) of the spool and interacts with pins (21) to cause uni-directional spool rotation through a number of pre-set angular positions as the spool is reciprocated. The valving component (18) of the spool is closed internally by wall (26) and has orifices (25) which come into and out of registration with body openings (29) as the spool is moved through its pre-set positions. When in registration, flow into the tool will leave the tool radially outwardly through openings (29); but when out of registration, the flow will be into chamber (28) of body central component (12), and back into the valving component (18) downstream of wall (26) through apertures (27).

Abstract: A method of translating a drawn or imagined model into a numerical format. Working from a paper sketch or interpreted seismic display, the geological horizons and faults are digitized in any order. If the horizon is unbroken, it is digitized continuously as one piece, if it is broken by faulting, it is digitized as a series of elements. Digitizing ceases if the horizon terminates within the model. During preconditioning the boundaries of the model are added as another element. A search is performed and if intersecting elements are found, the shortest limb is deleted. A second search locates elements which do not terminate at an intersection. If the element is from a horizon, it is projected until it intersects another element, if an unconnected fault element, the element is deleted back to its first intersection point. The first phase of cell construction identifies segments which connect only to themselves and produces single segment cells.

Abstract: A method for removing residual moveout includes sorting the results of common offset depth migration into common image point gathers. A subset of image point gathers are selected for analysis. Each common image point gather is separated vertically into windows, each of which centers on a strong event. For each window, all the offset traces are summed to produce a brute stack trace to be used as an anchor. All offsets are cross-correlated to the anchor to determine how much each trace window should be shifted to sum most constructively with the anchor. A set of dynamic shifts is produced, which when applied, will remove the residual moveouts and produce a truly flat image for stacking. These shifts vary with depth and offset and can be interpolated between the selected image point gathers.