Abstract: An electrode arrangement for use with a system for performing measurements on a biological subject, the electrode arrangement including: at least one substrate; and, a plurality of plate microstructures extending from the substrate, the microstructures being configured to breach the stratum corneum of the subject and wherein the microstructures include electrodes to allow signals to be applied to and/or received from the subject via the microstructures.

Abstract: A system for performing fluid level measurements on a biological subject, the system including at least one substrate including a plurality of microstructures configured to breach a stratum corneum of the subject, at least some microstructures including an electrode, a signal generator operatively connected to at least one microstructure to apply an electrical stimulatory signal to the at least one microstructure and at least one sensor operatively connected to at least one microstructure, the at least one sensor being configured to measure electrical response signals from at least one microstructure. The system also includes one or more electronic processing devices that determine measured response signals, the response signals being at least partially indicative of a bioimpedance and perform an analysis at least in part using the measured response signals to determine at least one indicator at least partially indicative of fluid levels in the subject.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: A system for performing fluid level measurements on a biological subject, the system including at least one substrate including a plurality of microstructures configured to breach a stratum corneum of the subject, at least some microstructures including an electrode, a signal generator operatively connected to at least one microstructure to apply an electrical stimulatory signal to the at least one microstructure and at least one sensor operatively connected to at least one microstructure, the at least one sensor being configured to measure electrical response signals from at least one microstructure. The system also includes one or more electronic processing devices that determine measured response signals, the response signals being at least partially indicative of a bioimpedance and perform an analysis at least in part using the measured response signals to determine at least one indicator at least partially indicative of fluid levels in the subject.

Abstract: A system for monitoring a fluid status of a biological subject, the system including at least one substrate including a plurality of microstructures including electrodes configured to breach a stratum corneum of the subject, a signal generator configured to apply an electrical stimulatory signal between electrodes on different microstructures, at least one signal sensor configured to measure electrical response signals between electrodes on different microstructures and one or more electronic processing devices that are configured to determine changes in bioimpedance using the measured electrical response signals and analyse the changes in bioimpedance to determine at least one indicator at least partially indicative of the fluid status of the subject.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: Disclosed is a system and method for performing measurements on a biological subject, and in one particular example, to performing measurements of analytes in a biological subject by breaching a functional barrier of the subject using microstructures, wherein the one or more microstructures include an aptamer for binding one or more analytes.

Abstract: Disclosed is a system and method for performing measurements on a biological subject, and in one particular example, to performing measurements of analytes in a biological subject by breaching a functional barrier of the subject using microstructures, wherein the one or more microstructures include molecularly imprinted polymer for binding one or more analytes.

Abstract: A system for delivering treatment to a biological subject, the system including: at least one substrate including a plurality of microstructures configured to breach a stratum corneum of the subject; at least one sensor operatively connected to at least one microstructure, the at least one sensor being configured to measure response signals from the at least one microstructure; at least one treatment delivery mechanism operatively coupled to at least one microstructure to deliver treatment via at least one microstructure; and, one or more electronic processing devices that are configured to control the at least one treatment delivery mechanism to thereby deliver treatment to the subject at least partially in accordance with the measured response signals.

Abstract: A system for detecting analytes in a biological subject, the system including at least one substrate including a plurality of microstructures configured to breach a stratum corneum of the subject, and wherein the one or more microstructures are responsive to a presence, absence, level or concentration of analytes to cause a change in appearance thereby indicating that a presence, absence, level or concentration of analytes has been detected.

Abstract: A system for performing measurements on a biological subject, the system including: at least one substrate including a plurality of plate microstructures configured to breach a stratum corneum of the subject; at least one sensor operatively connected to at least one microstructure, the at least one sensor being configured to measure response signals from the at least one microstructure; and, one or more electronic processing devices configured to: determine measured response signals; and, at least one of: provide an output based on measured response signals; perform an analysis at least in part using the measured response signals; and, store data at least partially indicative of the measured response signals.

Abstract: A system for performing measurements on a biological subject, the system including: at least one substrate including a plurality of microstructures configured to breach a stratum corneum of the subject; and, an actuator configured to apply a force to the substrate to cause the microstructures to at least one of pierce and penetrate the stratum corneum.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: A system for performing fluid level measurements on a biological subject, the system including at least one substrate including a plurality of microstructures configured to breach a stratum corneum of the subject, at least some microstructures including an electrode, a signal generator operatively connected to at least one microstructure to apply an electrical stimulatory signal to the at least one microstructure and at least one sensor operatively connected to at least one microstructure, the at least one sensor being configured to measure electrical response signals from at least one microstructure. The system also includes one or more electronic processing devices that determine measured response signals, the response signals being at least partially indicative of a bioimpedance and perform an analysis at least in part using the measured response signals to determine at least one indicator at least partially indicative of fluid levels in the subject.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: Disclosed are small molecule inhibitors of av136 integrin, and methods of using them to treat a number of diseases and conditions.

Abstract: The biodegradable urn planting system, also called a LIVING URN, is an apparatus capable of rapid degradation in soil that the user can fill with cremated remains, a pH neutralizing and sodium diluting material, soil, planting mix, wood chips, and a living plant (seedling or bare root stock). When one loses a loved one, it is often difficult to discern what to do with the remains (be they human or animal). Many towns and cities do not allow for burial, and storage of cremated remains can be problematic. The present invention seeks to provide a meaningful and tangible way for one to remember the loved one when the cremated remains are buried with a seedling that may be drop shipped and is appropriate for the environment of use. Thus, the seedling grows into a tree, providing comfort and a reminder of the deceased.

Abstract: Disclosed are small molecule inhibitors of ?v?6 integrin, and methods of using them to treat a number of diseases and conditions.