Abstract: A sterile tube connector for a fluid circuit system comprising a housing. A first opening is configured to receive a first length of tubing in communication with a first chamber. A second opening is configured for communicating with the first chamber when the tube connector is in an open configuration but not in a closed configuration. The second opening is configured to reversibly engage a third opening to form a second chamber. The third opening is configured for communicating with a second length of tubing. A first portion of the housing forming the first opening comprises a material at least partially permeable to a sterilization energy source for sterilizing contents of the second chamber.

Abstract: A system is provided for pumping fluid, with the system including a fluid pump and a cassette. The pump includes a motor and a piston that is movable toward and away from a flexible diaphragm of the cassette. A linkage connects the motor and the piston to move the piston toward and away from the diaphragm. At least a portion of the piston or the diaphragm is magnetized, with the other having at least a portion that is magnetized or formed of a ferromagnetic material, thereby magnetically coupling the piston and the diaphragm such that movement of the piston moves the diaphragm into and out of a cassette cavity aligned with the diaphragm and piston. Movement of the diaphragm into and out of the cavity changes the effective volume of the cavity, which has the effect of drawing fluid into or forcing fluid out of the cavity.

Abstract: A sterile tube connector for a fluid circuit system comprising a housing. A first opening is configured to receive a first length of tubing in communication with a first chamber. A second opening is configured for communicating with the first chamber when the tube connector is in an open configuration but not in a closed configuration. The second opening is configured to reversibly engage a third opening to form a second chamber. The third opening is configured for communicating with a second length of tubing. A first portion of the housing forming the first opening comprises a material at least partially permeable to a sterilization energy source for sterilizing contents of the second chamber.

Abstract: Fluid flow conduits and apparatus and methods for joining the conduits, preferably in a sterile manner, are disclosed. Each conduit has a polymeric open end that is sealed by a sealing member that may include a heating element. The polymeric end material is melted, the sealing members are moved to expose the melted open ends of the conduits and the ends are brought together to form a fused or welded connection between the conduits.

Abstract: A system is provided for pumping fluid, with the system including a fluid pump and a cassette. The pump includes a motor and a piston that is movable toward and away from a flexible diaphragm of the cassette. A linkage connects the motor and the piston to move the piston toward and away from the diaphragm. At least a portion of the piston or the diaphragm is magnetized, with the other having at least a portion that is magnetized or formed of a ferromagnetic material, thereby magnetically coupling the piston and the diaphragm such that movement of the piston moves the diaphragm into and out of a cassette cavity aligned with the diaphragm and piston. Movement of the diaphragm into and out of the cavity changes the effective volume of the cavity, which has the effect of drawing fluid into or forcing fluid out of the cavity.

Abstract: Fluid flow conduits (14a, 14b) and apparatus (40) and methods for joining the conduits (14a, 14b), preferably in a sterile manner, are disclosed. Each conduit (14, 14b) has a polymeric open end that is sealed by a sealing member (26a, 26b) that may include a heating element (28). The polymeric end material is melted, the sealing members (26a, 26b) are moved to expose the melted open ends of the conduits (14a, 14b) and the ends are brought together to form a fused or welded connection (12) between the conduits (14a, 14b).

Abstract: Fluid flow conduits and apparatus and methods for joining the conduits, preferably in a sterile manner, are disclosed. Each conduit has a polymeric open end that is sealed by a sealing member that may include a heating element. The polymeric end material is melted, the sealing members are moved to expose the melted open ends of the conduits and the ends are brought together to form a fused or welded connection between the conduits.

Abstract: Fluid flow conduits (14a, 14b) and apparatus (40) and methods for joining the conduits (14a, 14b), preferably in a sterile manner, are disclosed. Each conduit (14, 14b) has a polymeric open end that is sealed by a sealing member (26a, 26b) that may include a heating element (28). The polymeric end material is melted, the sealing members (26a, 26b) are moved to expose the melted open ends of the conduits (14a, 14b) and the ends are brought together to form a fused or welded connection (12) between the conduits (14a, 14b).