Abstract: A thrombectomy device for removing thrombus from a body lumen comprises an elongated catheter member (2) having a distal part and a proximal part, a thrombus blocking body (5) disposed on the distal part of the catheter member and radially expansible between a contracted orientation and an expanded, thrombus-blocking, orientation, a thrombus capture body (3) disposed on the distal part of the catheter member in an axially spaced-apart relationship to the thrombus blocking body, and radially expansible between a contracted orientation and an expanded, thrombus-capture, orientation, deployment means actuable to deploy and retract the thrombus capture body and thrombus blocking body; and an elongated control arm operably connected to the thrombus capture body. The thrombus capture body is a cage having an inwardly tapering leading end, the elongated control arm is operably connected to the leading end of the cage, and a thrombus extractor or macerator mechanism is disposed within the cage.

Abstract: A device suitable for use in a body lumen and comprises an elongated control member having a distal and a proximal end, and a radially expansible member disposed at or near the distal end and adapted for collection and/or shearing of matter (i.e. thrombus) from a wall of the body lumen (i.e. a vein or an artery). The radially expansible member has a proximal end and a distal end and is adjustable between a contracted orientation and an expanded orientation. The elongated control member comprising a proximal arm connected at or adjacent to the proximal end of the radially expansible member and a distal arm connected at or adjacent to the distal end of the radially expansible member such that movement of one arm relative to the other arm effects adjustment of the diameter or radial strength of the radially expansible member. The device comprises a control mechanism operatively connected to both arms and adapted to provide resistance to the movement of one arm relative to the other.

Abstract: A wearable device for detecting heart rhythm abnormalities, comprising: a sensor unit comprising at least one pulse oximeter; a processor unit; a memory unit; and a power unit comprising a battery and configured to disseminate battery power amongst various components of the wearable device; wherein, the at least one pulse oximeter is configured to measure optically a bloodstream at a sampling rate and output first data; wherein, the processor unit is configured to process the first data and determine a time for the processed first data to be automatically recorded in the memory unit; wherein, the processor unit is configured to dynamically adjust the sampling rate of the at least one pulse oximeter based on a predetermined event; and wherein, the processor unit is configured to control the power unit in such a way that the sampling rate is dynamically adjusted through applying varying power levels to the sensor unit and consequently the wearable device is operable to enable a duration up to 90 days for a sing

Abstract: A device suitable for use in a body lumen and comprises an elongated control member having a distal and a proximal end, and a radially expansible member disposed at or near the distal end and adapted for collection and/or shearing of matter (i.e. thrombus) from a wall of the body lumen (i.e. a vein or an artery). The radially expansible member has a proximal end and a distal end and is adjustable between a contracted orientation and an expanded orientation. The elongated control member comprising a proximal arm connected at or adjacent to the proximal end of the radially expansible member and a distal arm connected at or adjacent to the distal end of the radially expansible member such that movement of one arm relative to the other arm effects adjustment of the diameter or radial strength of the radially expansible member. The device comprises a control mechanism operatively connected to both arms and adapted to provide resistance to the movement of one arm relative to the other.

Abstract: A microwave ablation probe is disclosed. The microwave ablation probe includes an applicator arranged to apply microwave radiation to heat surrounding tissue; a feeding cable arranged to supply electromagnetic energy to the applicator; an antenna portion of an inner conductor of the feeding cable, the antenna portion extending distally from a distal end of an outer conductor of the feeding cable; and an overlapping portion of the inner conductor at least partly overlapping the antenna portion along the length of the antenna portion of the inner conductor and extending along a helical path around the antenna portion of the inner conductor.

Abstract: A microwave ablation probe (200; 300; 400), comprising: an applicator (202; 302; 402) arranged to apply microwave radiation to heat surrounding tissue; a feeding cable (204; 304; 404) arranged to supply electromagnetic energy to the applicator; a coolant flow path (206) via which coolant is able to flow; and a choke arranged to reduce power reflected from the applicator (202; 302; 402) along the feeding cable (204; 304; 404). The choke comprises a choke member (208; 209; 308; 408) cooled by coolant flowing in the coolant flow path (206). The choke member (208; 209; 308; 408) extends between two points spaced apart in a direction having at least a component parallel to a longitudinal axis of the feeding cable. The choke member (208; 209; 308; 408) comprises one or more turns extending around the longitudinal axis of the feeding cable. The choke member may be a spiral member (208; 308; 408).

Abstract: A thrombectomy device includes a handle at a proximal end portion of the device, a first tube connected to the handle, and a second tube extending to a distal end portion of the device. The thrombectomy device also includes a cage at the distal end portion of the device, the cage being adjustable between a contracted orientation and an expanded orientation and including a scraping element formed with one or more of a round wire, a flat wire, or a blade disposed between a proximal end portion of the cage and a distal end portion of the cage, and a suction device, including a source of suction connected to the proximal end portion of the device, the suction device being configured to apply suction towards an interior of the second tube and to an extraction passage formed between the first tube and the second tube in a radial direction.

Abstract: An implant (30) for a mammalian bone joint (3) for spacing a first bone (2) of the joint from a second bone (1) of the joint while allowing translational movement of the second bone in relation to the first bone is described. The implant comprises (a) a distal part (31) configured for intramedullary engagement with an end of the second bone, (b) a proximal part (34) having a platform (15) configured for non-engaging abutment of an end of the first bone and translational movement thereon, and (c) an articulating coupling (10, 16) provided between the distal and proximal ends allowing controlled articulation of the first and second bones. The bone-abutting platform is shaped to conform to and translate upon the end of the first bone. A kit for assembly to form the implant of the invention, and the use of the implant to treat osteoarthritis in a bone joint, are also described.

Abstract: An ablation probe (100; 200) comprising: an applicator (102; 202) arranged to apply radiation to heat surrounding tissue; a feeding cable (104; 204) arranged to supply electromagnetic energy to the applicator; a coolant flow path (106, 108) forming a coolant supply circuit; a tubular member (112; 212) housing at least part of the feeding cable (104; 204), wherein a part of the coolant flow path is defined by a space between the feeding cable and the tubular member; and a coupling body (114). The coupling body comprises: a cavity (116) in which the applicator (102; 204) is at least partly encapsulated; a coupling interface (118) at which the coupling body (114) is coupled to the tubular member; and a pointed distal tip (H4a) adapted for piercing tissue.

Abstract: A thrombectomy device includes a handle at a proximal end portion of the device, a first arm connected to the handle, and a second arm extending to a distal end portion of the device. The device may also include a cage at the distal end portion of the device, the cage being adjustable between a contracted orientation and an expanded orientation, the cage including a cutting element disposed between a proximal end portion of the cage and a distal end of the cage, the cutting element including one or more of a round wire, a flat wire, or a blade configured to remove matter from a body lumen when the cage is in the expanded orientation, and a macerator extending within the first arm and the second arm, the macerator including a helical element.

Abstract: A thrombectomy device includes a handle at a proximal end portion of the device, a cage at a distal end portion of the device, the cage being moveable between an expanded orientation and a contracted orientation, and a first tube extending from the proximal end portion of the device to at least a proximal end portion of the cage. The device also includes a second tube extending from the proximal end portion of the device to at least a distal end portion of the cage, and a self-adjusting control assembly including a biasing element coupled to one of the first tube or the second tube. The biasing element exerts an axial force to urge the cage toward the expanded orientation.

Abstract: An implant (30) for a mammalian bone joint (3) for spacing a first bone (2) of the joint from a second bone (1) of the joint while allowing translational movement of the second bone in relation to the first bone is described. The implant comprises (a) a distal part (31) configured for intramedullary engagement with an end of the second bone, (b) a proximal part (34) having a platform (15) configured for non-engaging abutment of an end of the first bone and translational movement thereon, and (c) an articulating coupling (10, 16) provided between the distal and proximal ends allowing controlled articulation of the first and second bones. The bone-abutting platform is shaped to conform to and translate upon the end of the first bone. A kit for assembly to form the implant of the invention, and the use of the implant to treat osteoarthritis in a bone joint, are also described.

Abstract: A thrombectomy device includes a handle at a proximal end portion of the device, a cage at a distal end portion of the device, the cage being moveable between an expanded orientation and a contracted orientation, and a first tube extending from the proximal end portion of the device to at least a proximal end portion of the cage. The device also includes a second tube extending from the proximal end portion of the device to at least a distal end portion of the cage, and a self-adjusting control assembly including a biasing element coupled to one of the first tube or the second tube. The biasing element exerts an axial force to urge the cage toward the expanded orientation.

Abstract: A valved introducer sheath (1) having a valve housing (17, 18) with a through-lumen and an inflatable cuff (2, 60, 70) disposed in the valve housing that can be inflated to occlude the through-lumen, is described. The device has an overflow tube (30) in fluidic connection with the inflatable cuff having a resiliently deformable overflow chamber (34). When the inflatable cuff is filled with inflation liquid, the cuff partly or fully occludes the through-lumen, thereby preventing blood pass through the lumen. When an interventional device is pushed through the lumen for use in a medical procedure, the pressure forces liquid from the cuff into the overflow tube, allowing the cuff to partly deflate. As the overflow chamber is resiliently deformable, the liquid is pressurised which maintains a seal between the inflatable cuff and the interventional device. Upon removal of the interventional device from the lumen, the overflow tube pushes fluid back into the cuff, allowing it to reinflate fully.

Abstract: A thrombectomy device includes a handle at a proximal end portion of the device, a first arm connected to the handle, and a second arm extending to a distal end portion of the device. The device may also include a cage at the distal end portion of the device, the cage being adjustable between a contracted orientation and an expanded orientation, the cage including a cutting element disposed between a proximal end portion of the cage and a distal end of the cage, the cutting element including one or more of a round wire, a flat wire, or a blade configured to remove matter from a body lumen when the cage is in the expanded orientation, and a macerator extending within the first arm and the second arm, the macerator including a helical element.

Abstract: A thrombectomy device includes a handle at a proximal end portion of the device, a first tube connected to the handle, and a second tube extending to a distal end portion of the device. The thrombectomy device also includes a cage at the distal end portion of the device, the cage being adjustable between a contracted orientation and an expanded orientation and including a scraping element formed with one or more of a round wire, a flat wire, or a blade disposed between a proximal end portion of the cage and a distal end portion of the cage, and a suction device, including a source of suction connected to the proximal end portion of the device, the suction device being configured to apply suction towards an interior of the second tube and to an extraction passage formed between the first tube and the second tube in a radial direction.

Abstract: An ablation probe (100; 200) suitable for insertion through the working channel of an intraluminal delivery device comprises an applicator (102; 202) arranged to apply radiation to heat surrounding tissue. The probe also comprises a feeding cable (104; 204) arranged to supply electromagnetic energy to the applicator (102; 202). The probe further comprises a first coolant flow path (106). There is also a deformable member (110; 210) arranged to move between an insertion configuration in which insertion of the probe is facilitated and a deployed configuration. A second coolant path (108), via which coolant is able to flow, is provided by the deformable member (110; 210) when in the deployed configuration. The probe further comprises a tube arranged to house a distal portion of the feeding cable, and the deformable member surrounds at least part of the tube, and the tube is formed from an elastic material.

Abstract: An ablation probe (1; 100; 200), comprising: an applicator (2; 102; 202) arranged to apply radiation to heat surrounding tissue; a feeding cable (4; 104; 204) arranged to supply electromagnetic energy to the applicator. The feeding cable comprises a distal portion (2a, 202a) and a proximal portion (2b; 202b). The distal portion of the feeding cable has a distal cross sectional size and the proximal portion of the feeding cable has a proximal cross sectional size, wherein the distal cross sectional size is less that the proximal cross sectional size. The ablation probe further comprises a connector (24; 224) arranged to mechanically and electrically couple the distal portion (2a, 202a) of the feeding cable (2; 202) to the proximal portion (2b; 202b) of the feeding cable (2; 202).

Abstract: A thrombectomy device for removing thrombus from a body lumen comprises an elongated catheter member (2) having a distal part and a proximal part, a thrombus blocking body (5) disposed on the distal part of the catheter member and radially expansible between a contracted orientation and an expanded, thrombus-blocking, orientation, a thrombus capture body (3) disposed on the distal part of the catheter member in an axially spaced-apart relationship to the thrombus blocking body, and radially expansible between a contracted orientation and an expanded, thrombus-capture, orientation, deployment means actuable to deploy and retract the thrombus capture body and thrombus blocking body; and an elongated control arm operably connected to the thrombus capture body. The thrombus capture body is a cage having an inwardly tapering leading end, the elongated control arm is operably connected to the leading end of the cage, and a thrombus extractor or macerator mechanism is disposed within the cage.

Abstract: Devices of the present disclosure may macerate and extract debris from inside a lumen. Such devices may include an extraction core, a tube including a side wall and a window in the side wall, and a rotatable helical formation disposed inside the tube. In some embodiments, the rotatable helical formation has a variable pitch.