Patents by Inventor Mark Bryan Mitchell

Mark Bryan Mitchell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Salts Of Methyl 2-((R))-(3-Chlorophenyl)((R)-1-((S)-2-(Methylamino)-3((R)-tetrahydro-2H-Pyran-3-YL)Propylcarbamoyl)Piperidin-3-YL)Methoxy)Ethylcarbamate
    Publication number: 20110112145
    Abstract: Disclosed are salts of methyl 2-((R)-(3-chlorophenyl)((R)-1-((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate and pharmaceutical compositions containing the same. Also disclosed are processes for the preparation thereof and methods for use thereof.
    Type: Application
    Filed: June 24, 2009
    Publication date: May 12, 2011
    Inventors: Nicole Marie Deschamps, David H. Igo, Mark Bryan Mitchell
  • Polymorphic and amorphous forms of the phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-ce]indol-6-one
    Patent number: 7268126
    Abstract: The present invention relates to novel polymorphic and amorphous forms of a phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: September 11, 2007
    Assignees: Agouron Pharmaceuticals, Inc., Cancer Research Technology Ltd.
    Inventors: Jia Liu, Naresh Nayyar, Ming Guo, Zhen-Ping Wu, Bennett Chaplin Borer, Aparna Nadig Srirangam, Mark Bryan Mitchell, Yi Li, Jan-Jon Chu
  • Methods of preparing indazole compounds
    Patent number: 7232910
    Abstract: The present invention relates to methods for preparing indazole compounds of formula I, which are useful as modulators and/or inhibitors of protein kinases. The present invention also relates to intermediate compounds useful in the preparation of compounds of formula I.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: June 19, 2007
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Brigitte Leigh Ewanicki, Erik Jon Flahive, Annie Judith Kasparian, Mark Bryan Mitchell, Michael David Perry, Stacy Ann O'Neill-Slawecki, Neal William Sach, James Edward Saenz, Bing Shi, Nebojsa Slobodan Stankovic, Jayaram Kasturi Srirangam, Qingping Tian, Shu Yu
  • Convergent processes for the synthesis of a GARFT inhibitor containing a methyl substituted thiophene core and intermediates therefor
    Publication number: 20040266796
    Abstract: The invention relates to processes for the preparation of a GARFT inhibitor containing a methyl substituted thiophene core having the following structure: 1
    Type: Application
    Filed: June 23, 2004
    Publication date: December 30, 2004
    Applicant: AGOURON PHARMACEUTICALS, INC.
    Inventors: Elena Dovalsantos, Erik Jon Flahive, Brian John Halden, Mark Bryan Mitchell, Wolfgang Reinhard Ludwig Notz, Stacy Ann O'Neill-Slawecki, Qingping Tian