Abstract: A method of monitoring a subject for the risk of Acute Mountain Sickness (AMS) includes obtaining real-time pulse arterial oxygen saturation (SpO2) measurements from the subject. The SpO2 measurements are transformed into a novel metric known as Accumulated Hypoxic Debt (AHD). The AHD metric is used as the independent variable in a longitudinal generalized linear mixed model to calculate the probability D that the subject is at risk of AMS. Based on the probability D, appropriate courses of action may be communicated to the subject via the output device of a wearable or portable monitor.

Abstract: A heat response monitor, comprises an accelerometer, a core temperature sensor, an estimation device, and an enabler. The estimation device uses accelerometry-based functionality to provide a gait-based heat stroke risk score, and the estimation device uses an estimated core temperature of a wearer of the core temperature sensor, to provide an estimated core temperature-based heat stroke risk score. The gait-based heat stroke risk score and the estimated core temperature-based heat stroke risk score are used to determine if a wearer of the heat response monitor is in risk of heat injury.

Abstract: A method of monitoring a subject for the risk of Acute Mountain Sickness (AMS) includes obtaining real-time pulse arterial oxygen saturation (SpO2) measurements from the subject. The SpO2 measurements are transformed into a novel metric known as Accumulated Hypoxic Debt (AHD). The AHD metric is used as the independent variable in a longitudinal generalized linear mixed model to calculate the probability D that the subject is at risk of AMS. Based on the probability D, appropriate courses of action may be communicated to the subject via the output device of a wearable or portable monitor.

Abstract: A system for determining food safety includes a recording device printed with one or more inks configured to change characteristics over predetermined time intervals, and a scanning device configured to extract encoded information from the recording device and convey the extracted information to an analysis service. The analysis service is configured to provide predictive modeling tools for analysis of the extracted information and provide at least one assessment of a food product bearing the recording device to the scanning device.

Abstract: The invention provides kits, methods and compositions of matter which improve the safety of vaccination. By combining the administration of antiviral drugs, particularly ester derivatives of cidofovir, with the administration of viral vaccines, particularly the variola vaccine DryVax, side effects of the vaccine are diminished without significantly affecting the effectiveness of the vaccine.

Abstract: The invention provides kits, methods and compositions of matter which improve the safety of vaccination. By combining the administration of antiviral drugs, particularly ester derivatives of cidofovir, with the administration of viral vaccines, particularly the variola vaccine DryVax, side effects of the vaccine are diminished without significantly affecting the effectiveness of the vaccine.