Patents by Inventor Mark Bunnage

Mark Bunnage has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICALLY ACTIVE COMPOUNDS
    Publication number: 20060293347
    Abstract: Compounds of the formula (I): wherein R1, R2, R4 and R13 are as defined or a pharmaceutically or veterinarily acceptable salt or polymorph thereof, or a pharmaceutically or veterinarily acceptable solvate or pro-drug thereof: are potent and selective inhibitors of type 5 cyclic guanosine 3?,5?-monophosphate phosphodiesterase (cGMP PDE5) and have utility in the treatment of, inter alia, male erectile dysfunction (MED) and female sexual dysfunction (FSD).
    Type: Application
    Filed: August 11, 2006
    Publication date: December 28, 2006
    Inventors: Mark Bunnage, Keith DeVries, Laurence Harris, Philip Levett, John Mathias, Joanna Negri, Stephen Street, Albert Wood
  • Nicotinamide derivatives useful as pde4 inhibitors
    Publication number: 20060178408
    Abstract: This invention relates to nicotinamide derivatives of general formula (I): in which R1, Z and R2 have the meanings defined herein, and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of such derivatives.
    Type: Application
    Filed: July 13, 2004
    Publication date: August 10, 2006
    Inventors: Christopher Barber, Mark Bunnage, John Harvey, John Mathias
  • Compounds useful for the treatment of diseases
    Publication number: 20050234097
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Application
    Filed: March 16, 2005
    Publication date: October 20, 2005
    Inventors: Alan Brown, Charlotte Lane, Paul Glossop, David Price, Russell Lewthwaite, Mark Bunnage, Kim James, Graham Lunn
  • Compounds for the treatment of diseases
    Publication number: 20050222128
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Application
    Filed: March 21, 2005
    Publication date: October 6, 2005
    Inventors: Alan Brown, Mark Bunnage, Charlotte Lane, Russell Lewthwaite, Paul Glossop, Kim James, David Price
  • Formamide derivatives for the treatment of diseases
    Publication number: 20050215590
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Application
    Filed: March 21, 2005
    Publication date: September 29, 2005
    Inventors: Alan Brown, Mark Bunnage, Charlotte Lane, Russell Lewthwaite, Paul Glossop, Kim James, David Price
  • Compounds for the treatment of diseases
    Publication number: 20050215542
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds of the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Application
    Filed: March 21, 2005
    Publication date: September 29, 2005
    Inventors: Alan Brown, Mark Bunnage, Charlotte Lane, Russell Lewthwaite, Paul Glossop, Kim James, David Price
  • Sulfonamide derivatives for the treatment of diseases
    Publication number: 20050182091
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Application
    Filed: January 19, 2005
    Publication date: August 18, 2005
    Inventors: Alan Brown, Mark Bunnage, Paul Glossop, Kim James, Charlotte Lane, Russel Lewthwaite, Ian Moses, David Price, Nicholas Thomson
  • Indole derivatives useful for the treatment of diseases
    Publication number: 20050085526
    Abstract: The invention relates to indole derivatives and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The indole derivatives according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Application
    Filed: October 5, 2004
    Publication date: April 21, 2005
    Inventors: Alan Brown, Justin Bryans, Mark Bunnage, Paul Glossop, Charlotte Lane, Russell Lewthwaite, Simon Mantell
  • Compounds
    Publication number: 20050043326
    Abstract: This invention relates to nicotinamide derivatives of general formula (I): in which R1, Z and R2 have the meanings defined herein, and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of such derivatives.
    Type: Application
    Filed: July 20, 2004
    Publication date: February 24, 2005
    Inventors: Christopher Barber, Mark Bunnage, John Harvey, John Mathias
  • Nicotinamide derivatives useful as PDE4 inhibitors
    Publication number: 20050038033
    Abstract: This invention relates to nicotinamide derivatives of general formula (I): in which R1, R2 and R3 have the meanings defined herein, and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of such derivatives.
    Type: Application
    Filed: July 20, 2004
    Publication date: February 17, 2005
    Inventors: Mark Bunnage, John Mathias
  • Compounds
    Publication number: 20050020611
    Abstract: This invention relates to nicotinamide derivatives of general formula (I): in which R1, Z and R2 have the meanings defined herein, and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of such derivatives.
    Type: Application
    Filed: July 20, 2004
    Publication date: January 27, 2005
    Inventors: Christopher Barber, Mark Bunnage, John Harvey, John Mathias