Abstract: A microactuator may be configured by activating a source of electromagnetic radiation to heat and melt a selected set of phase-change plugs embedded in a substrate of the microactuator, pressurizing a common pressure chamber adjacent to each of the plugs to deform the melted plugs, and deactivating the source of electromagnetic radiation to cool and solidify the melted plugs.

Abstract: An acoustical fluid control mechanism and a method of controlling fluid flow of a working fluid with the acoustical fluid control mechanism are provided. The mechanism comprises a resonance chamber that defines a cavity. The resonance chamber has a port. The cavity is sealed from the ambient but for the port for enabling oscillatory flow of a working fluid into and out of the cavity upon exposure of the resonance chamber to an acoustic signal containing a tone at a frequency that is substantially similar to a particular resonance frequency of the resonance chamber. The mechanism further includes a rectifier for introducing directional bias to the oscillatory flow of the working fluid through the port. The rectifier has an inlet connected to the port and an outlet for transmitting the directional flow of the working fluid away from the cavity. The outlet is in fluid communication with the port of the resonance chamber at least during transmission of the directional flow of the working fluid therethrough.

Abstract: The movement and mixing of microdroplets through microchannels is described employing silicon-based microscale devices, comprising microdroplet transport channels, reaction regions, electrophoresis modules, and radiation detectors. The discrete droplets are differentially heated and propelled through etched channels. Electronic components are fabricated on the same substrate material, allowing sensors and controlling circuitry to be incorporated in the same device.

Abstract: A modular microfluidic system comprising a base substrate, a plurality of microfluidic assembly blocks, and an adhesive component is provided. Each individual microfluidic assembly block defines a channel and has a sidewall defining an aperture into the channel. When the plurality of microfluidic assembly blocks are arranged on the base substrate, the aperture into the channel of one microfluidic assembly block aligns with the aperture of another microfluidic assembly block with the channels thereof connected along a plane parallel to the base substrate thereby forming a channel network defined by the plurality of microfluidic assembly blocks. The subject invention also provides a method of assembling a microfluidic device. The method comprising the steps of providing the base substrate, providing the plurality of microfluidic assembly blocks, and arranging the plurality of microfluidic assembly blocks on the base substrate.

Abstract: A microactuator may be configured by activating a source of electromagnetic radiation to heat and melt a selected set of phase-change plugs embedded in a substrate of the microactuator, pressurizing a common pressure chamber adjacent to each of the plugs to deform the melted plugs, and deactivating the source of electromagnetic radiation to cool and solidify the melted plugs.

Abstract: A system and method of acquiring and transmitting uterine EMG signals is disclosed, where a signal processing module processes incoming uterine EMG signals from a patient and wirelessly transmits a processed signal to an information relaying device. The information relaying device is then configured to download the processed signal and transmit the signal to a call center or health care facility for physician evaluation. The system is ambulatory, thus allowing the patient to record and transmit uterine EMG signals anywhere a satisfactory transmission may be made.

Abstract: A heat exchanger for an ice machine has the form of a cylinder. In some embodiments, the cylinder is made from an extrusion of a metal such as an aluminum alloy. The heat exchanger includes inner and outer cylindrical walls and one or more refrigeration passages positioned between the inner and outer walls. The inner and outer walls are separated from each other by connecting structures defining the refrigeration passages. The heat exchanger can be extruded as a rectangular panel and subsequently formed into a cylindrical form. Alternatively, the heat exchanger can be extruded as a cylinder, or as an arcuate cylindrical segment in which several of such segments are subsequently joined together (as by welding) into a cylinder. Ice machines that feature ice formation on both the inner and outer walls of the cylinder are also disclosed.

Abstract: The movement and mixing of microdroplets through microchannels is described employing silicon-based microscale devices, comprising microdroplet transport channels, reaction regions, electrophoresis modules, and radiation detectors. The discrete droplets are differentially heated and propelled through etched channels. Electronic components are fabricated on the same substrate material, allowing sensors and controlling circuitry to be incorporated in the same device.

Abstract: A heat exchanger for an ice machine has the form of a cylinder. In some embodiments, the cylinder is made from an extrusion of a metal such as an aluminum alloy. The heat exchanger includes inner and outer cylindrical walls and one or more refrigeration passages positioned between the inner and outer walls. The inner and outer walls are separated from each other by connecting structures defining the refrigeration passages. The heat exchanger can be extruded as a rectangular panel and subsequently formed into a cylindrical form. Alternatively, the heat exchanger can be extruded as a cylinder, or as an arcuate cylindrical segment in which several of such segments are subsequently joined together (as by welding) into a cylinder. Ice machines that feature ice formation on both the inner and outer walls of the cylinder are also disclosed.

Abstract: A method of positioning lumber in a given orientation in a handling apparatus having a base frame, a longitudinal transport assembly, and at least two gripper arm support platforms with a pair of gripper arms positioned on each of the support platforms. A work piece is gripped with the gripper arms without the work piece engaging the longitudinal transport assembly. The gripper arms are adjusted on at least one of the support platforms in a direction generally perpendicular to the longitudinal transport assembly in order to selectively position the work piece. The work piece is then brought into engagement with the transport assembly and the gripper arms are released from the work piece.

Abstract: The movement and mixing of microdroplets through microchannels is described employing silicon-based microscale devices, comprising microdroplet transport channels, reaction regions, electrophoresis modules, and radiation detectors. The discrete droplets are differentially heated and propelled through etched channels. Electronic components are fabricated on the same substrate material, allowing sensors and controlling circuitry to be incorporated in the same device.

Abstract: An acoustical fluid control mechanism and a method of controlling fluid flow of a working fluid with the acoustical fluid control mechanism are provided. The mechanism comprises a resonance chamber that defines a cavity. The resonance chamber has a port. The cavity is sealed from the ambient but for the port for enabling oscillatory flow of a working fluid into and out of the cavity upon exposure of the resonance chamber to an acoustic signal containing a tone at a frequency that is substantially similar to a particular resonance frequency of the resonance chamber. The mechanism further includes a rectifier for introducing directional bias to the oscillatory flow of the working fluid through the port. The rectifier has an inlet connected to the port and an outlet for transmitting the directional flow of the working fluid away from the cavity. The outlet is in fluid communication with the port of the resonance chamber at least during transmission of the directional flow of the working fluid therethrough.

Abstract: The present invention relates to a system for measuring the impedance of a skin/electrode interface and selectively modifying the system gain of the monitoring circuit to compensate for errors introduced by variations in the skin/electrode impedance. More particularly, a simplified, low-cost method for measuring and compensating for skin/electrode impedance variations is provided. The skin/electrode impedance measuring circuit and determines a system gain correction factor which may be applied to the measured signal using a software algorithm, thereby eliminating the need to change the circuit topology with a programmable gain amplifier or programmable resistor network.

Abstract: A system and method for acquiring and processing uterine EMG signals from a maternal patient. Raw uterine EMG signals are acquired and processed in a central unit designed to isolate the patient and any internal circuitry from electrical shock. The central unit has a circuit board that amplifies and filters the EMG signal, then transmits the signal to an AID converter, after which the digitized signal is transmitted to a computer for further processing of the signal and subsequent display of a signal representative of uterine activity. The system and method provide a more accurate measurement of uterine EMG signals than a tocodynamometer or IUPC, and are useful in predicting delivery or monitoring the patient during post partum uterine activity.

Abstract: A modular microfluidic system comprising a base substrate, a plurality of microfluidic assembly blocks, and an adhesive component is provided. Each individual microfluidic assembly block defines a channel and has a sidewall defining an aperture into the channel. When the plurality of microfluidic assembly blocks are arranged on the base substrate, the aperture into the channel of one microfluidic assembly block aligns with the aperture of another microfluidic assembly block with the channels thereof connected along a plane parallel to the base substrate thereby forming a channel network defined by the plurality of microfluidic assembly blocks. The subject invention also provides a method of assembling a microfluidic device. The method comprising the steps of providing the base substrate, providing the plurality of microfluidic assembly blocks, and arranging the plurality of microfluidic assembly blocks on the base substrate.

Abstract: A heat exchanger for an ice machine has the form of a cylinder. In some embodiments, the cylinder is made from an extrusion of a metal such as an aluminum alloy. The heat exchanger includes inner and outer cylindrical walls and one or more refrigeration passages positioned between the inner and outer walls. The inner and outer walls are separated from each other by connecting structures defining the refrigeration passages. The heat exchanger can be extruded as a rectangular panel and subsequently formed into a cylindrical form. Alternatively, the heat exchanger can be extruded as a cylinder, or as an arcuate cylindrical segment in which several of such segments are subsequently joined together (as by welding) into a cylinder. Ice machines that feature ice formation on both the inner and outer walls of the cylinder are also disclosed.

Abstract: A microactuator may be configured by activating a source of electromagnetic radiation to heat and melt a selected set of phase-change plugs embedded in a substrate of the microactuator, pressurizing a common pressure chamber adjacent to each of the plugs to deform the melted plugs, and deactivating the source of electromagnetic radiation to cool and solidify the melted plugs.

Abstract: The present invention provides methods and systems for running reactions, in particular, biological reactions and assays, in a Rayleigh-Bénard convection cell. The utilization of Rayleigh-Bénard convection principles for conducting biological or biochemical reactions is a novel application. In order to use Rayleigh-Bénard convection for conducting biological or biochemical reactions it is necessary to create a temperature differential in a solution of reactants.

Abstract: A high capacity, continuous production blast freezer includes an insulated enclosure, a refrigeration system supplying cold air to the enclosure and a plurality of trays containing comestibles to be frozen. A tray advancement or pusher mechanism advances a first tray into the enclosure and then advances a second tray into the enclosure, pushing the first tray further into the enclosure. Gradually a first level of the enclosure is filled with trays. An elevator mechanism at both ends of the enclosure allows the trays reaching the end of the enclosure to advance to a second level, and the tray advancement mechanism advances the tray out of the elevator onto the second level. Eventually, as additional trays are pushed into the enclosure, the second level and then optionally further levels of the enclosure are filled with trays.

Abstract: Small molecule polycationic agents are used to modulate or interrupt biological processes by binding to oligosaccharide-based biomolecules. Compounds that inhibit nitric oxide, TNF? or other immunomodulators are provided and are useful for treating immunological disease and disease of an infectious disorder.