Abstract: A method may comprise disposing a nuclear magnetic resonance logging tool into a wellbore, identifying an upper limit of an amplitude for tool motion, identifying a frequency range based at least in part on the upper limit of the amplitude for tool motion, measuring the one or more frequencies from the echo train, and performing a frequency-domain processing of the one or more frequencies to suppress distortions in an echo train. A system may comprise a nuclear magnetic resonance logging tool and an information handling system. The nuclear magnetic resonance logging tool may further comprise an electromagnetic transmitter configured to emit a magnetic field, a radio frequency transmitter configured to transmit a pulse and one or more refocusing pulses, and a receiver configured to detect one or more frequencies from an echo train.

Abstract: A method may comprise disposing a nuclear magnetic resonance logging tool into a wellbore, identifying an upper limit of an amplitude for tool motion, identifying a frequency range based at least in part on the upper limit of the amplitude for tool motion, measuring the one or more frequencies from the echo train, and performing a frequency-domain processing of the one or more frequencies to suppress distortions in an echo train. A system may comprise a nuclear magnetic resonance logging tool and an information handling system. The nuclear magnetic resonance logging tool may further comprise an electromagnetic transmitter configured to emit a magnetic field, a radio frequency transmitter configured to transmit a pulse and one or more refocusing pulses, and a receiver configured to detect one or more frequencies from an echo train.

Abstract: NMR microprobe detectors and methodologies that provide enhanced signal sensitivity for low-volume sample detection and analysis are described. In one embodiment the microprobe detector is a flat wire detector with a strip conductor having a length and width and ratio greater than 5 with a substantially uniform surface positioned on a low loss substrate in contact with a sample holder having a generally thin wall or at least a thin portion near where the sample probing and analysis occur.

Abstract: The present invention is a two-domain, bi-functional fusion protein that functions as a molecular switch wherein the free energy released by the folding of a first domain of the fusion protein drives an unfolding of a second domain of the fusion protein, and vice versa. The molecular structure of the fusion protein is engineered so that, at any time, the folding of the first domain necessarily unfolds the other domain, and vice versa, thereby making the folded and unfolded states of the first and second domains mutually exclusive. This is accomplished by the insertion of ubiquitin insert protein into a surface loop of barnase target protein subject to the structural design criterion that the N-C terminal length of the ubiquitin insert protein is at least two-times greater than the C?-C? alpha-carbon-alpha-carbon length of the surface loop of the barnase target protein.

Abstract: The present invention is a model for a mutually exclusive domain folding molecular switch comprising a two-domain, bifunctional fusion protein wherein the free energy released by the folding of a first domain of the fusion protein drives an unfolding of a second domain of the fusion protein, and vice versa. The molecular structure of the fusion protein is engineered so that, at any time, the folding of the first domain necessarily unfolds the other domain, and vice versa, thereby making the folded and unfolded states of the first and second domains mutually exclusive. This is accomplished by the insertion of an exemplary insert protein into a surface loop of an exemplary target protein subject to a novel structural design criterion wherein the N-C terminal length of the exemplary insert protein is at least two-times greater than the C&agr;-C&agr; length of the surface loop of the exemplary target protein.