Patents by Inventor Mark C. Noe

Mark C. Noe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidine-2,4,6-trione metalloproteinase inhibitors
    Publication number: 20020132822
    Abstract: The present invention relates to pyrimidine-2,4,6-trione metalloproteinase inhibitors of the formula 1
    Type: Application
    Filed: October 25, 2001
    Publication date: September 19, 2002
    Inventors: Mark C. Noe, Lawrence A. Reiter, Martin J. Wythes
  • Gem substituted hydroxamic acids
    Publication number: 20020019534
    Abstract: A compound of the formula 1
    Type: Application
    Filed: March 27, 2001
    Publication date: February 14, 2002
    Inventor: Mark C. Noe
  • Hydroxy pipecolate hydroxamic acid derivatives
    Patent number: 6329397
    Abstract: A compound of the formula wherein R1, R2 R3, R4 R5, R6, R7, R8, R9 and Ar are as defined above, useful in the treatment of a condition selected from the group consisting of arthritis, cancer, and other diseases characterized by matrix metalloproteinase or mammalian reprolysin activity. In addition, the compounds of the present invention may be used in combination therapy with standard non-steroidal anti-inflammatory drugs (NSAID'S), COX-2 inhibitors and analgesics, and in combination with cytotoxic drugs such as adriamycin, daunomycin, cis-platinum, etoposide, taxol, taxotere and other alkaloids, such as vincristine, in the treatment of cancer.
    Type: Grant
    Filed: August 12, 1999
    Date of Patent: December 11, 2001
    Assignee: Pfizer
    Inventors: Kim F. McClure, Mark C. Noe, Michael A. Letavic, Louis S. Chupak
  • Isothiazole derivatives useful as anticancer agents
    Publication number: 20010020034
    Abstract: The present invention relates to compounds of the formula 1 1
    Type: Application
    Filed: March 9, 2001
    Publication date: September 6, 2001
    Inventors: Eric R. Larson, Mark C. Noe, Thomas G. Gant
  • Isothiazole derivatives useful as anticancer agents
    Patent number: 6235764
    Abstract: The present invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein X1, R1, R2 and R3 are as defined herein. The invention also relates to pharmaceutical compositions containing the above compounds and to methods treating hyperproliferative disorders in mammals by administering the above compounds.
    Type: Grant
    Filed: May 21, 1999
    Date of Patent: May 22, 2001
    Assignee: Pfizer Inc.
    Inventors: Eric R. Larson, Mark C. Noe, Thomas G. Gant