Abstract: The invention relates to compounds of Formula (I): wherein R1, R2 and X are as defined herein. The invention also relates to pharmaceutical compositions and methods of treating bacterial infections using compounds of Formula (I).

Abstract: A thermal management system for a spacecraft module includes a baseplate and wall system that is precharacterized to provide a given level of thermal performance regardless of an orientation of the spacecraft relative to a source of solar energy. The system is characterized at a worst-case hot orientation, and at a worst-case cold orientation. The characterization provides a maximum temperature and a minimum temperature of components mounted on the baseplate as a function of the height of the walls. The height of the walls is selected to provide a suitable temperature range for the components, based on the power dissipation of the components. The system is designed to be symmetric, so that this temperature range is assured regardless of the orientation of the spacecraft.

Abstract: An apparatus for assessing a person's hand strength including means for engaging the hand. The apparatus including means for determining the strength of the hand based on a twisting action with the hand of the engaging means relative to the determining means. The engaging means is connected to the determining means. A method for assessing a person's hand strength including the steps of gripping a first object having a first diameter with the hand by the person. There is the step of twisting the first object with the hand. There is the step of measuring torque with a torque sensor, connected to the first object, of the object as it is being twisted by the hand.

Abstract: Prepare a composite protective coating for metal substrates such as steel used in fabricating metal pipe or conduit. The coating, when applied to a flat metal surface, retains its bond to the metal through cold forming processes such as those used in making ribbed steel pipe. The coating resembles a sandwich of a reinforcing material layer between two adhesive films.

Abstract: The present invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein Z, X, X1, R1, R2 and R3 are as defined herein as it relates to pharmaceutical compositions containing the above compounds for the treatment of disorders mediated by angiogenesis in mammals by administration of the above compounds.

Abstract: Prepare a composite protective coating for metal substrates such as steel used in fabricating metal pipe or conduit. The coating, when applied to a flat metal surface, retains its bond to the metal through cold forming processes such as those used in making ribbed steel pipe. The coating resembles a sandwich of a reinforcing material layer between two adhesive films.