Abstract: Methods and corresponding uses are provided for treating a cancer in a patient in need thereof, comprising administering an effective amount of sodium trans-[tetrachloridobis(1H-indazole)ruthenate(III)] (BOLD-100). BOLD-100 may be used in combination with an effective amount of an inhibitor of ataxia-telangiectasia mutated and Rad3-related protein kinase (ATRi).

Abstract: An attachment including a casing having an air inlet for receiving an airflow from a hair styling apparatus, a hair engaging member, supported by the casing, and adapted to move relative to the casing between a first position and a second position under the action of an over-centre mechanism. First and second airflow outlets are formed between the casing and the hair engaging member when the hair engaging member is in the first and second position, respectively.

Abstract: A toy comprising a frame and an inverting toy. In some embodiments, the inverting toy includes an invertible shell having a first surface and a second surface, the invertible shell configured to protrude outward in a first direction with respect to the frame until a depressing force on the first surface or the second surface in a second direction causes the shell to invert and protrude in the second direction with respect to the frame, wherein the first direction and the second direction are substantially opposite, an edge member formed at an edge of the invertible shell and configured to secure the invertible shell to the frame, and a pulling member formed on and protruding outward from the first surface of the invertible shell.

Abstract: A toy comprising a frame and an inverting toy. In some embodiments, the inverting toy includes an invertible shell having a first surface and a second surface, the invertible shell configured to protrude outward in a first direction with respect to the frame until a depressing force on the first surface or the second surface in a second direction causes the shell to invert and protrude in the second direction with respect to the frame, wherein the first direction and the second direction are substantially opposite, an edge member formed at an edge of the invertible shell and configured to secure the invertible shell to the frame, and a pulling member formed on and protruding outward from the first surface of the invertible shell.

Abstract: A multi-degree-of-freedom electromagnetic machine that may be operated as a motor, a generator, or a motor-generator, includes a first structure and a second structure. The first structure comprises a first conductor, a second conductor, and a third conductor, each of which follows a different trajectory. The first, second, and third conductors together form a general shape of a surface. The second structure is disposed adjacent to the first structure and includes a magnet that emanates a magnetic field. The magnet has at least one of its magnetic poles facing the surface. A Lorentz force affects relative movement between the first structure and the second structure when the magnetic field that emanates from the at least one magnetic pole interacts with electrical currents within any of the electrical conductors.

Abstract: A multi-degree-of-freedom electromagnetic machine that may be operated as a motor, a generator, or a motor-generator, includes a first structure and a second structure. The first structure comprises a first conductor, a second conductor, and a third conductor, each of which follows a different trajectory. The first, second, and third conductors together form a general shape of a surface. The second structure is disposed adjacent to the first structure and includes a magnet that emanates a magnetic field. The magnet has at least one of its magnetic poles facing the surface. A Lorentz force affects relative movement between the first structure and the second structure when the magnetic field that emanates from the at least one magnetic pole interacts with electrical currents within any of the electrical conductors.

Abstract: It is often required to send a plurality of streams of data in parallel between two network nodes in a synchronous transmission network and also to maintain a particular alignment between those streams of data. This is particularly required when the streams of data are to be transmitted over a wide area network, for example, for data mirroring applications. Virtual concatenation is used for each of the individual data streams as known in the art and in addition, the individual virtual concatenation processes are synchronized or co-ordinated. At a destination node it is then possible to realign the individual data streams with respect to one another.

Abstract: The invention provides a system (1) for providing power measurements using a current sensing element (2) located at a supply line and a voltage sensing element (3) located remotely from said supply line location. Power measurement is enabled by using a communications link (4) to correlate current and voltage measurements.

Abstract: In order to enable nodes with a single protocol switch core to be used in a synchronous transmission network carrying both SDH and SONET traffic then one option is to convert traffic between protocols at the various network nodes. For example, if the network node has a switch core arranged for SONET, then when SDH traffic arrives at that node it can first be converted to SONET before being processed by the switch core and then converted back to SDH again if required. Known methods of converting between SONET and SDH are not suited for use at egress points of network nodes where pointer alignment processes do not occur. A new method of converting between SONET and SDH is described which overcomes these problems by reordering the position of stuff columns.

Abstract: One aspect of the invention provides an ingress apparatus comprising a signal processing apparatus for receiving an incoming data frame and locating the position of path overhead, and a monitoring apparatus arranged to extract information from the located path overhead. The ingress apparatus further includes an insertion apparatus for receiving, from the monitoring apparatus, information extracted from the path overhead of one or more signal path, and being further arranged to insert the extracted information into a respective data frame component which occupies a fixed position in a data frame. Thus, information which would normally occupy a non-fixed position in a data frame is moved to a fixed position. As a result, the information can subsequently be accessed without having to employ relatively complex apparatus for locating information which occupies a non-fixed position.

Abstract: A technique for provisioning cross-connects in network switching environment includes receiving a portion of the an input data stream including having header data and the payload data, the payload data occurring at a first offset relative to the header data and generating a delayed version of the portion of the input data stream. The technique also includes generating a portion of a retimed data stream by selecting between the portion of the input data stream and the delayed version of the portion of the input data stream, the retimed data stream including the header data and the payload data, the payload data occurring at a second offset relative to the header data.

Abstract: A method and system for providing single stage pointer and overhead processing is disclosed. In accordance with one embodiment of the invention, data including bytes of each of multiple types of overhead data is received at a logical element of a communications network. The logical element includes a labeler to label the bytes of each of the multiple types of overhead data and a pointer processor to read the labeled bytes and perform specific operations corresponding to the label, wherein the bytes of at least one type of overhead data are labeled based on feedback provided by the pointer processor to the labeler.

Abstract: A method and apparatus that allows egress pointer smoothing data by evaluating the average fill of an elastic store. For one embodiment of the invention, an elastic store implements a plurality of independent FIFOs, each FIFO having a write pointer and a read pointer, the write pointer including a marking pointer field and valid flag field. An incoming byte is received to a location within a traffic memory and the write pointer is used to instruct the traffic memory to indicate that the incoming bit has been received to the location. The valid flag field is set to indicate that the value at the location is currently valid.

Abstract: A wheeled loading machine includes a body mounting a loading arm, a ground engaging structure including a front axle which carries a front pair of ground engaging wheels and a rear axle which carries a rear pair of ground engaging wheels, the loading arm being mounted at a position towards a rear of the machine for up and down movement about a generally horizontal axis, and the loading arm extending forwardly beside a cab which is mounted at one side of the body, to an outermost end which is beyond a front of the body, and the loading arm having at its outermost end a mounting for a loading implement and the arm being extendible to vary the length of the loading arm, and each axle being suspended from the body by a respective suspension, each of the ground engaging wheels being drivable by an engine of the machine through a mechanical transmission, and the machine including a braking system for braking each wheel, the braking system including a brake control system which provides a brake anti-locking function

Abstract: A method and apparatus that allows egress pointer smoothing data by evaluating the average fill of an elastic store. For one embodiment of the invention, by measuring the average fill, the 3 bytes of SOH and 87 bytes of data are taken together in each sample, and the relative phase of ingress and egress frames does not impact the fill depth calculation. For one such embodiment, the calculation is performed by summing the elastic store fill over a full row and increment/decrement decisions based on that average figure provide smooth rate of pointers coming out even as a section overhead moves through the frame.

Abstract: A method and system for providing single stage pointer and overhead processing is disclosed. In accordance with one embodiment of the invention, data including bytes of each of multiple types of overhead data is received at a logical element of a communications network. The logical element includes a labeler to label the bytes of each of the multiple types of overhead data and a pointer processor to read the labeled bytes and perform specific operations corresponding to the label, wherein the bytes of at least one type of overhead data are labeled based on feedback provided by the pointer processor to the labeler.

Abstract: A self-steering switch includes an input stage, and output stage, and an arbitration stage. The input stage is configured to accumulate a surplus of switching cycles, allowing the arbitration stage to resolve traffic congestion without blockage. The arbitration stage includes a configuration memory, one or more arbitrators, and one or more buffers in which queuing of memory requests is conducted. Contention for memory access is resolved by the arbitrators on a fair basis, for example through a round-robin scheme.