Patents by Inventor Mark Cassidy

Mark Cassidy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11626200
    Abstract: Digital pathology is the concept of capturing digital images from glass microscope slides in order to record, visualize, analyze, manage, report, share and diagnose pathology specimens. The present disclosure is directed to a desktop slide scanner, which enables pathologists to scan slides at a touch of a button. Included is a workflow for reliable imaging, diagnosis, quantification, management, and sharing of a digital pathology library. Also disclosed herein is an analysis framework that provides for pattern recognition of biological samples represented as digital images to automatically quantitatively score normal cell parameters against disease state parameters. The framework provides a pathologist with an opportunity to see what the algorithm is scoring, and simply agree, or edit the result. This framework offers a new tool to enhance the precision of the current standard of care.
    Type: Grant
    Filed: February 17, 2020
    Date of Patent: April 11, 2023
    Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.
    Inventors: Mark Cassidy Cridlin Lloyd, Marilyn M. Bui
  • Patent number: 10733726
    Abstract: Systems and methods for personalized cancer therapy using analysis of pathology slides to target regions in a single sample that interrogates the feature data of a relatively large number of cells. The disclosure describes pathology case review tools of the future which include analysis, visualization and prediction modeling to provide novel information to the pathologist for the diagnosis of disease. This disclosure further describes a user interface to assist the physicians that make that diagnosis, pathologists. Complex computer learning algorithms will combine and mine these data sets to recommend optimal treatment strategies. A computer interface is provided which allows a pathologist to access those data instantly to make a more informed and accurate diagnosis.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: August 4, 2020
    Assignee: H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE
    Inventors: Mark Cassidy Cridlin Lloyd, Marilyn Yuanxin Ma Bui, Katarzyna Ann Rejniak, Munish Puri
  • Publication number: 20200184193
    Abstract: Digital pathology is the concept of capturing digital images from glass microscope slides in order to record, visualize, analyze, manage, report, share and diagnose pathology specimens. The present disclosure is directed to a desktop slide scanner, which enables pathologists to scan slides at a touch of a button. Included is a workflow for reliable imaging, diagnosis, quantification, management, and sharing of a digital pathology library. Also disclosed herein is an analysis framework that provides for pattern recognition of biological samples represented as digital images to automatically quantitatively score normal cell parameters against disease state parameters. The framework provides a pathologist with an opportunity to see what the algorithm is scoring, and simply agree, or edit the result. This framework offers a new tool to enhance the precision of the current standard of care.
    Type: Application
    Filed: February 17, 2020
    Publication date: June 11, 2020
    Inventors: Mark Cassidy Cridlin Lloyd, Marilyn M. Bui
  • Patent number: 10565430
    Abstract: Digital pathology is the concept of capturing digital images from glass microscope slides in order to record, visualize, analyze, manage, report, share and diagnose pathology specimens. The present disclosure is directed to a desktop slide scanner, which enables pathologists to scan slides at a touch of a button. Included is a workflow for reliable imaging, diagnosis, quantification, management, and sharing of a digital pathology library. Also disclosed herein is an analysis framework that provides for pattern recognition of biological samples represented as digital images to automatically quantitatively score normal cell parameters against disease state parameters. The framework provides a pathologist with an opportunity to see what the algorithm is scoring, and simply agree, or edit the result. This framework offers a new tool to enhance the precision of the current standard of care.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: February 18, 2020
    Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.
    Inventors: Mark Cassidy Cridlin Lloyd, Marilyn M. Bui
  • Publication number: 20190087954
    Abstract: Systems and methods for personalized cancer therapy using analysis of pathology slides to target regions in a single sample that interrogates the feature data of a relatively large number of cells. The disclosure describes pathology case review tools of the future which include analysis, visualization and prediction modeling to provide novel information to the pathologist for the diagnosis of disease. This disclosure further describes a user interface to assist the physicians that make that diagnosis, pathologists. Complex computer learning algorithms will combine and mine these data sets to recommend optimal treatment strategies. A computer interface is provided which allows a pathologist to access those data instantly to make a more informed and accurate diagnosis.
    Type: Application
    Filed: July 9, 2018
    Publication date: March 21, 2019
    Inventors: Mark Cassidy Cridlin Lloyd, Marilyn Yuanxin Ma Bui, Katarzyna Ann Rejniak, Munish Puri
  • Publication number: 20190054451
    Abstract: The invention provides a catalyst comprising iron oxide, nickel, ceria or palladium supported on stainless steel foam. The catalyst is effective in oxidising aromatic compounds such as toluene and o-cresol and, advantageously, is particularly effective when the oxidation is carried out at elevated temperatures that correspond to temperatures attained in areas of the aircraft where cabin air is recirculated.
    Type: Application
    Filed: February 10, 2017
    Publication date: February 21, 2019
    Inventors: John Thomas Sirr IRVINE, Mark CASSIDY, Sneh JAIN
  • Patent number: 10049447
    Abstract: Systems and methods for personalized cancer therapy using analysis of pathology slides to target regions in a single sample that interrogates the feature data of a relatively large number of cells. The disclosure describes pathology case review tools of the future which include analysis, visualization and prediction modeling to provide novel information to the pathologist for the diagnosis of disease. This disclosure further describes a user interface to assist the physicians that make that diagnosis, pathologists. Complex computer learning algorithms will combine and mine these data sets to recommend optimal treatment strategies. A computer interface is provided which allows a pathologist to access those data instantly to make a more informed and accurate diagnosis.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: August 14, 2018
    Assignee: H. Lee Moffitt Cancer Center and Research Insititute, Inc.
    Inventors: Mark Cassidy Cridlin Lloyd, Marilyn Yuanxin Ma Bui, Katarzyna Anna Rejniak, Munish Puri
  • Publication number: 20180075284
    Abstract: Digital pathology is the concept of capturing digital images from glass microscope slides in order to record, visualize, analyze, manage, report, share and diagnose pathology specimens. The present disclosure is directed to a desktop slide scanner, which enables pathologists to scan slides at a touch of a button. Included is a workflow for reliable imaging, diagnosis, quantification, management, and sharing of a digital pathology library. Also disclosed herein is an analysis framework that provides for pattern recognition of biological samples represented as digital images to automatically quantitatively score normal cell parameters against disease state parameters. The framework provides a pathologist with an opportunity to see what the algorithm is scoring, and simply agree, or edit the result. This framework offers a new tool to enhance the precision of the current standard of care.
    Type: Application
    Filed: September 8, 2017
    Publication date: March 15, 2018
    Inventors: Mark Cassidy Cridlin Lloyd, Marilyn M. Bui
  • Patent number: 9760760
    Abstract: Digital pathology is the concept of capturing digital images from glass microscope slides in order to record, visualize, analyze, manage, report, share and diagnose pathology specimens. The present disclosure is directed to a desktop slide scanner, which enables pathologists to scan slides at a touch of a button. Included is a workflow for reliable imaging, diagnosis, quantification, management, and sharing of a digital pathology library. Also disclosed herein is an analysis framework that provides for pattern recognition of biological samples represented as digital images to automatically quantitatively score normal cell parameters against disease state parameters. The framework provides a pathologist with an opportunity to see what the algorithm is scoring, and simply agree, or edit the result. This framework offers a new tool to enhance the precision of the current standard of care.
    Type: Grant
    Filed: January 18, 2013
    Date of Patent: September 12, 2017
    Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.
    Inventors: Mark Cassidy Cridlin Lloyd, Marilyn M. Bui
  • Publication number: 20160314580
    Abstract: Systems and methods for personalized cancer therapy using analysis of pathology slides to target regions in a single sample that interrogates the feature data of a relatively large number of cells. The disclosure describes pathology case review tools of the future which include analysis, visualization and prediction modeling to provide novel information to the pathologist for the diagnosis of disease. This disclosure further describes a user interface to assist the physicians that make that diagnosis, pathologists. Complex computer learning algorithms will combine and mine these data sets to recommend optimal treatment strategies. A computer interface is provided which allows a pathologist to access those data instantly to make a more informed and accurate diagnosis.
    Type: Application
    Filed: November 6, 2014
    Publication date: October 27, 2016
    Inventors: Mark Cassidy Cridlin Lloyd, Marilyn Yuanxin Ma Bui, Katarzyna Anna Rejniak, Munish Puri
  • Publication number: 20150003716
    Abstract: Digital pathology is the concept of capturing digital images from glass microscope slides in order to record, visualize, analyze, manage, report, share and diagnose pathology specimens. The present disclosure is directed to a desktop slide scanner, which enables pathologists to scan slides at a touch of a button. Included is a workflow for reliable imaging, diagnosis, quantification, management, and sharing of a digital pathology library. Also disclosed herein is an analysis framework that provides for pattern recognition of biological samples represented as digital images to automatically quantitatively score normal cell parameters against disease state parameters. The framework provides a pathologist with an opportunity to see what the algorithm is scoring, and simply agree, or edit the result. This framework offers a new tool to enhance the precision of the current standard of care.
    Type: Application
    Filed: January 18, 2013
    Publication date: January 1, 2015
    Inventors: Mark Cassidy Cridlin Lloyd, Marilyn M. Bui
  • Patent number: 7951509
    Abstract: A solid oxide fuel cell stack includes a plurality of solid oxide fuel cells, wherein each solid oxide fuel cell comprises an electrolyte located between an anode electrode and a cathode electrode, a plurality of gas separators, and at least one compliant cathode contact material. The contact material may be a metallic felt, foam or mesh, an electrically conductive glass or an electrically conductive ceramic felt located between at least one of the plurality of gas separators and a cathode electrode of an adjacent solid oxide fuel cell.
    Type: Grant
    Filed: April 2, 2007
    Date of Patent: May 31, 2011
    Assignee: Bloom Energy Corporation
    Inventors: Mark Cassidy, Stephen Couse
  • Patent number: 7892691
    Abstract: A solid oxide fuel cell component (12) comprises a plurality of solid oxide fuel cells (24) arranged in spaced apart relationship, and in electrical series, on a surface of the porous gas permeable support structure (16). Each solid oxide fuel cell (24) comprises a dense gas tight electrolyte member (28), a porous gas permeable first electrode (26) and a porous gas permeable second electrode (30). Each electrolyte (28) is arranged in contact with a corresponding one of the first electrodes (26), each second electrode (30) is arranged in contact with a corresponding one of the electrolytes (28). Each of the first electrodes (26) is arranged in contact with the surface of the support structure (16). The interconnectors (32), the peripheral seal layer (34) and the electrolytes (28) are arranged to encapsulate all of the first electrodes (26) except for the surfaces of the first electrodes (26) in contact with the surface of the support structure (16) to prevent leakage of reactant from the first electrodes (16).
    Type: Grant
    Filed: January 27, 2010
    Date of Patent: February 22, 2011
    Assignee: Rolls-Royce plc
    Inventors: Michael J. Day, Frederick J. Gardner, Mark Cassidy, Nigel Brandon, Nigel T. Hart
  • Patent number: 7732075
    Abstract: A solid oxide fuel cell component (12) comprises a plurality of solid oxide fuel cells (24) arranged in spaced apart relationship, and in electrical series, on a surface of the porous gas permeable support structure (16). Each solid oxide fuel cell (24) comprises a dense gas tight electrolyte member (28), a porous gas permeable first electrode (26) and a porous gas permeable second electrode (30). Each electrolyte (28) is arranged in contact with a corresponding one of the first electrodes (26), each second electrode (30) is arranged in contact with a corresponding one of the electrolytes (28). Each of the first electrodes (26) is arranged in contact with the surface of the support structure (16). The interconnectors (32), the peripheral seal layer (34) and the electrolytes (28) are arranged to encapsulate all of the first electrodes (26) except for the surfaces of the first electrodes (26) in contact with the surface of the support structure (16) to prevent leakage of reactant from the first electrodes (16).
    Type: Grant
    Filed: March 17, 2009
    Date of Patent: June 8, 2010
    Assignee: Rolls-Royce plc
    Inventors: Michael J. Day, Frederick J. Gardner, Mark Cassidy, Nigel Brandon, Nigel T. Hart
  • Publication number: 20100129727
    Abstract: A solid oxide fuel cell component (12) comprises a plurality of solid oxide fuel cells (24) arranged in spaced apart relationship, and in electrical series, on a surface of the porous gas permeable support structure (16). Each solid oxide fuel cell (24) comprises a dense gas tight electrolyte member (28), a porous gas permeable first electrode (26) and a porous gas permeable second electrode (30). Each electrolyte (28) is arranged in contact with a corresponding one of the first electrodes (26), each second electrode (30) is arranged in contact with a corresponding one of the electrolytes (28). Each of the first electrodes (26) is arranged in contact with the surface of the support structure (16). The interconnectors (32), the peripheral seal layer (34) and the electrolytes (28) are arranged to encapsulate all of the first electrodes (26) except for the surfaces of the first electrodes (26) in contact with the surface of the support structure (16) to prevent leakage of reactant from the first electrodes (16).
    Type: Application
    Filed: January 27, 2010
    Publication date: May 27, 2010
    Applicant: ROLLS-ROYCE PLC
    Inventors: Michael J. Day, Frederick J. Gardner, Mark Cassidy, Nigel Brandon, Nigel T. Hart
  • Publication number: 20090291346
    Abstract: A solid oxide electrolyzer cell or a solid oxide reversible fuel cell includes a solid oxide electrolyte. It may also include at least one of a first gadolinia doped ceria interfacial layer in contact with a first side of the electrolyte and a second gadolinia doped ceria interfacial layer in contact with a second side of the electrolyte. It may also include a fuel electrode including a cermet containing nickel and one or both of a doped zirconia and gadolinia doped ceria. It may also include an oxidant electrode including an LSM and one or both of a doped zirconia and gadolinia doped ceria.
    Type: Application
    Filed: August 5, 2009
    Publication date: November 26, 2009
    Inventors: Darren Hickey, Mark Cassidy
  • Publication number: 20090194219
    Abstract: A solid oxide fuel cell component (12) comprises a plurality of solid oxide fuel cells (24) arranged in spaced apart relationship, and in electrical series, on a surface of the porous gas permeable support structure (16). Each solid oxide fuel cell (24) comprises a dense gas tight electrolyte member (28), a porous gas permeable first electrode (26) and a porous gas permeable second electrode (30). Each electrolyte (28) is arranged in contact with a corresponding one of the first electrodes (26), each second electrode (30) is arranged in contact with a corresponding one of the electrolytes (28). Each of the first electrodes (26) is arranged in contact with the surface of the support structure (16). The interconnectors (32), the peripheral seal layer (34) and the electrolytes (28) are arranged to encapsulate all of the first electrodes (26) except for the surfaces of the first electrodes (26) in contact with the surface of the support structure (16) to prevent leakage of reactant from the first electrodes (16).
    Type: Application
    Filed: March 17, 2009
    Publication date: August 6, 2009
    Inventors: MICHAEL J. DAY, FREDERICK J. GARDNER, MARK CASSIDY, NIGEL BRANDON, NIGEL T. HART
  • Patent number: 7531260
    Abstract: A solid oxide fuel cell component (12) comprises a plurality of solid oxide fuel cells (24) arranged in spaced apart relationship, and in electrical series, on a surface of the porous gas permeable support structure (16). Each solid oxide fuel cell (24) comprises a dense gas tight electrolyte member (28), a porous gas permeable first electrode (26) and a porous gas permeable second electrode (30). Each electrolyte (28) is arranged in contact with a corresponding one of the first electrodes (26), each second electrode (30) is arranged in contact with a corresponding one of the electrolytes (28). Each of the first electrodes (26) is arranged in contact with the surface of the support structure (16). The interconnectors (32), the peripheral seal layer (34) and the electrolytes (28) are arranged to encapsulate all of the first electrodes (26) except for the surfaces of the first electrodes (26) in contact with the surface of the support structure (16) to prevent leakage of reactant from the first electrodes (16).
    Type: Grant
    Filed: April 3, 2003
    Date of Patent: May 12, 2009
    Assignee: Rolls-Royce plc
    Inventors: Michael J. Day, Frederick J. Gardner, Mark Cassidy, Nigel Brandon, Nigel T. Hart
  • Patent number: 7399546
    Abstract: A solid oxide fuel cell (10) comprises an anode electrode (12), a cathode electrode (14) and an electrolyte (16) between the anode electrode (12) and the cathode electrode (14). A gaseous fuel is supplied to an anode chamber (18) partially defined by the anode electrode (12) and a gaseous oxidant is supplied to a cathode chamber (20) partially defined by the cathode electrode (14). The electrolyte (16) comprises a first dense non-porous layer (22), a second porous layer (24) on the first dense non-porous layer (22) and a third dense non-porous layer (26) on the second porous layer (24). The anode electrode (12) is arranged on the first dense non-porous layer (22) and the cathode electrode (14) is arranged on the third dense non-porous layer (26). The second porous layer (24) acts as a buffer between the first dense non-porous layer (22) and the third dense non-porous layer (26) to prevent defects propagating between the layers (22,26) and to prevent fuel and oxidant leaking through the electrolyte (16).
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: July 15, 2008
    Assignee: Rolls-Royce plc
    Inventors: Nigel T Hart, Gary J Wright, Gerard D Agnew, Mark Cassidy
  • Publication number: 20070231676
    Abstract: A solid oxide fuel cell stack includes a plurality of solid oxide fuel cells, wherein each solid oxide fuel cell comprises an electrolyte located between an anode electrode and a cathode electrode, a plurality of gas separators, and at least one compliant cathode contact material. The contact material may be a metallic felt, foam or mesh, an electrically conductive glass or an electrically conductive ceramic felt located between at least one of the plurality of gas separators and a cathode electrode of an adjacent solid oxide fuel cell.
    Type: Application
    Filed: April 2, 2007
    Publication date: October 4, 2007
    Inventors: Mark Cassidy, Stephen Couse