Patents by Inventor Mark Charest

Mark Charest has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of tetracyclines and analogues thereof
    Publication number: 20050282787
    Abstract: The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The modular synthesis of tetracyclines and tetracycline analogs described provides an efficient and enantioselective route to a variety of tetracycline analogs and polycyclines previously inaccessible via earlier tetracycline syntheses and semi-synthetic methods. These analogs may be used as anti-microbial agents or anti-proliferative agents in the treatment of diseases of humans or other animals.
    Type: Application
    Filed: May 20, 2005
    Publication date: December 22, 2005
    Inventors: Andrew Myers, Mark Charest, Christian Lerner, Jason Brubaker, Dionicio Siegel
  • Organic compounds
    Publication number: 20050234042
    Abstract: Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula I
    Type: Application
    Filed: April 6, 2005
    Publication date: October 20, 2005
    Inventors: Mark Palermo, Sushil Sharma, Christopher Straub, Run-Ming Wang, Leigh Zawel, Yanlin Zhang, Zhuoliang Chen, Yaping Wang, Fan Yang, Wojciech Wrona, Gang Liu, Mark Charest, Feng He