Abstract: A manifold adaptor plate useful as a gasket having liquid pathways which permit passing of a filtrate, a feed and a retentate wherein admixture of the filtrate with the feed or the retentate is prevented is provided and is formed of an elastomeric layer, a rigid intermediate layer and a polymer layer. The elastomeric layer functions as a gasket and is bonded to the polymeric layer through the liquid pathways of the intermediate plate. An elastomer layer may be formed on both layers as well and optionally a second polymer layer between the intermediate layer and the second elastomer layer may also be used.

Abstract: A manifold adaptor plate useful as a gasket having liquid pathways which permit passing of a filtrate, a feed and a retentate wherein admixture of the filtrate with the feed or the retentate is prevented is provided and is formed of an elastomeric layer, a rigid intermediate layer and a polymer layer. The elastomeric layer functions as a gasket and is bonded to the polymeric layer through the liquid pathways of the intermediate plate. An elastomer layer may be formed on both layers as well and optionally a second polymer layer between the intermediate layer and the second elastomer layer may also be used.

Abstract: A manifold adaptor plate useful as a gasket having liquid pathways which permit passing of a filtrate, a feed and a retentate wherein admixture of the filtrate with the feed or the retentate is prevented is provided and is formed of an elastomeric layer, a rigid intermediate layer and a polymer layer. The elastomeric layer functions as a gasket and is bonded to the polymeric layer through the liquid pathways of the intermediate plate. An elastomer layer may be formed on both layers as well and optionally a second polymer layer between the intermediate layer and the second elastomer layer may also be used.

Abstract: The present invention relates to the formation of a gasket, sealing area or O-ring, such as a gasket on a screen for a filtration module such as a TFF or NF cassette or an O-ring on the outlet of a filter cartridge wherein the seal is proud of at least one surface of the screen. Preferably, the seal is molded to the filter component, more preferably it is injection molded to the component. The seal maybe formed of any elastomeric material such as thermoplastic, thermoplastic elastomers, thermosets and rubber, both natural and synthetic. The molded seal provides better sealing, allows for a variation in heights and geometries, and provides better cleanliness and lower extractables than the currently used adhesives or conventional gaskets or O-rings.

Abstract: A filter construction is provided having a packing density of at least 300 square meters of active membrane filter area per cubic meter of external volume of said filter construction, said filter constructed of materials characterized by less than 250 mg of extracted contamination per m2 of wetted material.

Abstract: The present invention relates to the formation of a gasket, sealing area or O-ring, such as a gasket on a screen for a filtration module such as a TFF or NF cassette or an O-ring on the outlet of a filter catridge wherein the seal is proud of at least one surface of the screen. Preferably, the seal is molded to the filter component. more preferably it is injection molded to the component. The seal may be formed of any elastomeric material such as thermoplastic, thermoplastic elastomers, thermosets and rubber, both natural and synthetic. The molded seal provides better sealing, allows for a variation in heights and geometries, and provides better cleanliness and lower extractables than the currently used adhesives or conventional gaskets or O-rings.

Abstract: A filtration module is provided having a packing density of at least 300 square meters of active membrane filter area per cubic meter of external volume of said filter construction, said filter constructed of materials characterized by less than 250 mg of extracted contamination per m2 of extracted wetted material. The filtration module includes a membrane composite layer comprising a filtrate screen sealed to each surface of a membrane layer with a thermoplastic polymeric composition positioned about the periphery of the filtrate screen.