Patents by Inventor Mark Chiu

Mark Chiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bispecific EGFR/C-Met Antibodies
    Publication number: 20170275367
    Abstract: Bispecific EGFR/c-Met antibodies and methods of making and using the molecules.
    Type: Application
    Filed: June 7, 2017
    Publication date: September 28, 2017
    Inventors: Mark Chiu, Sheri Moores, Joost Neijssen, Paul Parren, Janine Schuurman
  • COMPOSITIONS AND METHODS FOR PHAGOCYTE DELIVERY OF ANTI-STAPHYLOCOCCAL AGENTS
    Publication number: 20170233461
    Abstract: The present application generally relates to multi-specific molecules that bind to multiple bacterial virulence factors, methods for producing these binding molecules, and the use of these binding molecules to treat bacterial infections. In particular, the binding molecules comprise at least two binding domains, preferably an antibody or antibody fragment and an alternative scaffold. The first binding domain is capable of binding to a glycosylated staphylococcal surface protein, preferably an SDR-containing protein. The second binding domain is capable of binding to a staphylococcal leukotoxin, preferably LukAB, LukD or LukE. These multi-specific binding compounds have killing activity against staphylococci and, thus, can be used in the treatment and/or amelioration of a Staphylococcus infection, including methicillin-resistant Staphylococcus aureus.
    Type: Application
    Filed: May 2, 2017
    Publication date: August 17, 2017
    Inventors: Victor J. TORRES, Randall J. BREZSKI, Anthony LYNCH, William STROHL, Brian WHITAKER, Mark CHIU, Peter T. BUCKLEY, Keri DORN, Michelle KINDER
  • Bispecific Anti-TNF-Alpha/IL17A Antibodies and Anti-TNF-Alpha Antibodies and Methods of Their Use
    Publication number: 20170218092
    Abstract: The present invention relates to bispecific anti-TNF-?/IL-17A antibodies and anti-TNF-? antibodies, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
    Type: Application
    Filed: January 27, 2017
    Publication date: August 3, 2017
    Inventors: Mark Chiu, Jennifer Nemeth-Seay, Tatiana Ort, Fang Shen
  • Bispecific EGFR/c-Met antibodies
    Patent number: 9695242
    Abstract: Bispecific EGFR/c-Met antibodies and methods of making and using the molecules.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: July 4, 2017
    Assignee: Janssen Biotech, Inc.
    Inventors: Mark Chiu, Sheri Moores, Joost Neijssen, Paul Parren, Janine Schuurman
  • Compositions and methods for phagocyte delivery of anti-staphylococcal agents
    Patent number: 9644023
    Abstract: The present application generally relates to multi-specific molecules that bind to multiple bacterial virulence factors, methods for producing these binding molecules, and the use of these binding molecules to treat bacterial infections. In particular, the binding molecules comprise at least two binding domains, preferably an antibody or antibody fragment and an alternative scaffold. The first binding domain is capable of binding to a glycosylated staphylococcal surface protein, preferably an SDR-containing protein. The second binding domain is capable of binding to a staphylococcal leukotoxin, preferably LukAB, LukD or LukE. These multi-specific binding compounds have killing activity against staphylococci and, thus, can be used in the treatment and/or amelioration of a Staphylococcus infection, including methicillin-resistant Staphylococcus aureus.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: May 9, 2017
    Assignees: New York University, Janssen Biotech, Inc.
    Inventors: Victor J. Torres, Randall J. Brezski, Anthony Lynch, William Strohl, Brian Whitaker, Mark Chiu, Peter T. Buckley, Keri Dorn, Michelle Kinder
  • Bispecific EGFR/C-Met Antibodies
    Publication number: 20170101475
    Abstract: Bispecific EGFR/c-Met antibodies and methods of making and using the molecules.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Inventors: Mark Chiu, Sheri Moores, Joost Neijssen, Paul Parren, Janine Schuurman
  • Bispecific EGFR/c-Met antibodies
    Patent number: 9593164
    Abstract: Bispecific EGFR/c-Met antibodies and methods of making and using the molecules.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: March 14, 2017
    Assignee: Janssen Biotech, Inc.
    Inventors: Mark Chiu, Sheri Moores, Joost Neijssen, Paul Parren, Janine Schuurman
  • Bispecific EGFR/c-Met antibodies
    Patent number: 9580508
    Abstract: Bispecific EGFR/c-Met antibodies and methods of making and using the molecules.
    Type: Grant
    Filed: May 21, 2014
    Date of Patent: February 28, 2017
    Assignee: Janssen Biotech, Inc.
    Inventors: Mark Chiu, Sheri Moores, Joost Neijssen, Paul Parren, Janine Schuurman
  • COMPOSITIONS AND METHODS FOR PHAGOCYTE DELIVERY OF ANTI-STAPHYLOCOCCAL AGENTS
    Publication number: 20150210756
    Abstract: The present application generally relates to multi-specific molecules that bind to multiple bacterial virulence factors, methods for producing these binding molecules, and the use of these binding molecules to treat bacterial infections. In particular, the binding molecules comprise at least two binding domains, preferably an antibody or antibody fragment and an alternative scaffold. The first binding domain is capable of binding to a glycosylated staphylococcal surface protein, preferably an SDR-containing protein. The second binding domain is capable of binding to a staphylococcal leukotoxin, preferably LukAB, LukD or LukE. These multi-specific binding compounds have killing activity against staphylococci and, thus, can be used in the treatment and/or amelioration of a Staphylococcus infection, including methicillin-resistant Staphylococcus aureus.
    Type: Application
    Filed: December 9, 2014
    Publication date: July 30, 2015
    Inventors: Victor J. Torres, Randall J. Brezski, Anthony Lynch, William Strohl, Brian Whitaker, Mark Chiu, Peter T. Buckley, Keri Dorn, Michelle Kinder
  • Bispecific EGFR/C-Met Antibodies
    Publication number: 20140255408
    Abstract: Bispecific EGFR/c-Met antibodies and methods of making and using the molecules.
    Type: Application
    Filed: May 21, 2014
    Publication date: September 11, 2014
    Applicant: Janssen Biotech, Inc.
    Inventors: Mark Chiu, Sheri Moores, Joost Neijssen, Paul Parren, Janine Schuurman
  • Bispecific EGFR/C-Met Antibodies
    Publication number: 20140141000
    Abstract: Bispecific EGFR/c-Met antibodies and methods of making and using the molecules.
    Type: Application
    Filed: November 21, 2013
    Publication date: May 22, 2014
    Applicant: Janssen Biotech, Inc.
    Inventors: Mark Chiu, Sheri Moores, Joost Neijssen, Paul Parren, Janine Schuurman