Patents by Inventor Mark Coles

Mark Coles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic retinoids (in cell modulation)
    Patent number: 11833203
    Abstract: There are described novel compounds of formula I: (I) in which, in which A1, A2, A3, A4, R1 and R2 are each as herein defined, for use in the treatment or alleviation of an RAR mediated condition; and methods related thereto.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: December 5, 2023
    Inventors: Andrew Whiting, Carrie Ambler, Mark Coles, David Chisholm
  • Synthetic retinoids (in cell modulation)
    Patent number: 11324825
    Abstract: There are described novel compounds of formula I: (I) in which, in which A1, A2, A3, A4, R1 and R2 are each as herein defined, for use in the treatment or alleviation of an RAR mediated condition; and methods related thereto.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: May 10, 2022
    Inventors: Andrew Whiting, Carrie Ambler, Mark Coles, David Chisholm
  • Synthetic Retinoids (in Cell Modulation)
    Publication number: 20190209684
    Abstract: There are described novel compounds of formula I: (I) in which, in which A1, A2, A3, A4, R1 and R2 are each as herein defined, for use in the treatment or alleviation of an RAR mediated condition; and methods related thereto.
    Type: Application
    Filed: August 9, 2017
    Publication date: July 11, 2019
    Applicant: University of Durham
    Inventors: Andrew Whiting, Carrie Ambler, Mark Coles, David Chisholm
  • SYNTHETIC RETINOIDS (IN CELL MODULATION)
    Publication number: 20190209685
    Abstract: There are described novel compounds of formula I: (I) in which, in which A1, A2, A3, A4, R1 and R2 are each as herein defined, for use in the treatment or alleviation of an RAR mediated condition; and methods related thereto.
    Type: Application
    Filed: March 19, 2019
    Publication date: July 11, 2019
    Applicant: University of Durham
    Inventors: Andrew Whiting, Carrie Ambler, Mark Coles, David Chisholm
  • Assessment Method
    Publication number: 20100223681
    Abstract: A method of assessing the viability of a cell comprises incubating the cell in a culture medium. The culture medium includes a plurality of amino acids and the change in concentration in the medium of at least one amino acid is determined.
    Type: Application
    Filed: November 2, 2009
    Publication date: September 2, 2010
    Inventors: Henry J. Leese, Mark Coles, Roger Sturmey
  • Method to improve directional survey accuracy
    Patent number: 4956921
    Abstract: A method is proposed for better determining the azimuth and inclination of a borehole in which a priori information regarding the magnitude of the earth's gravitational field strength, its magnetic field strength and direction are utilized to constrain the measured components of the earth's gravitational and magnetic field vectors. The constrained fit method adjusts the accelerometer and the magnetometer tri-axis measurements to optimize agreement between the measured data and the a priori magnetic and gravity field strengths and the magnetic dip angle. The adjustment that is selected is that which produces the least increase in the statistical measure .chi..sup.2.
    Type: Grant
    Filed: February 21, 1989
    Date of Patent: September 18, 1990
    Assignee: Anadrill, Inc.
    Inventor: Mark Coles