Patents by Inventor Mark Comebise

Mark Comebise has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidinylpyrazoles as Tgf-Beta Inhibitors
    Publication number: 20080171755
    Abstract: The invention is based on the discovery that compounds of formula (I) possess high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. The invention features a compound of formula (I) and uses thereof: formula (I).
    Type: Application
    Filed: August 24, 2005
    Publication date: July 17, 2008
    Inventors: Wen-Cherng Lee, Lihong Sun, Claudio Chuaqui, Mark Comebise, Juswinder Singh, Feng Shan